Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 9
232
Views
2
CrossRef citations to date
0
Altmetric
Molecular Toxicology

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways

, , , , , , , , , , & show all
Pages 1106-1115 | Received 18 Apr 2018, Accepted 12 Oct 2018, Published online: 30 Jan 2019

References

  • Abramoff MD, Magalhaes PJ, Ram SJ. (2004). Image processing with ImageJ. Biophotonics International 11:36–42.
  • Akinbami LJ, Moorman JE, Bailey C, et al. (2012). Trends in asthma prevalence, health care use, and mortality in the United States, 2001–2010. NCHS data brief, 94:1–8.
  • Amberbir A, Medhin G, Hanlon C, et al. (2014). Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 year follow-up of an Ethiopian birth cohort. PloS One 9:e93869.
  • An SS, Wang WC, Koziol-White CJ, et al. (2012). TAS2R activation promotes airway smooth muscle relaxation despite beta(2)-adrenergic receptor tachyphylaxis. Am J Physiol Lung Cell Mol Physiol 303:L304–11.
  • Arrowsmith JB, Kennedy DL, Kuritsky JN, Faich GA. (1987). National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985. Pediatrics 79:858–63.
  • Barr RG, Wentowski CC, Curhan GC, et al. (2004). Prospective study of acetaminophen use and newly diagnosed asthma among women. Am J Respir Crit Care Med 169:836–41.
  • Beasley R, Clayton T, Crane J, et al. (2008). Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6–7 years: analysis from Phase Three of the ISAAC programme. Lancet 372:1039–48.
  • Beasley RW, Clayton TO, Crane J, et al. (2011). Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: International Study of Asthma and Allergies in Childhood Phase Three. Am J Respir Crit Care Med 183:171–8.
  • Chand N, Dhawan BN, Srimal RC, et al. (1980). Reactivity of trachea, bronchi, and lung strips to histamine and carbachol in rhesus monkeys. J Appl Physiol Respir Environ Exerc Physiol 49:729–34.
  • Cooper PR, Kurten RC, Zhang J, et al. (2011). Formoterol and salmeterol induce a similar degree of beta2-adrenoceptor tolerance in human small airways but via different mechanisms. Br J Pharmacol 163:521–32.
  • Cooper PR, Lamb R, Day ND, et al. (2009). TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation. Am J Physiol Lung Cell Mol Physiol 297:L530–7.
  • Deshpande, DA, Wang, WC, McIlmoyle EL, et al. (2010). Bitter Taste receptors on airway smooth muscle bronchodilator by localized calcium signaling and reverse obstruction. Nat Med 16:1299–304.
  • Etminan M, Sadatsafavi M, Jafari S, et al. (2009). Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis. Chest 136:1316–23.
  • Hinson JA, Roberts DW, James LP. (2010). Mechanisms of acetaminophen-induced liver necrosis. Handb Exp Pharmacol 196:369–405.
  • James LP, Letzig L, Simpson PM, et al. (2009). Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure. Drug Metab Dispos 37:1779–84.
  • Kaufman DW, Kelly JP, Rosenberg L, et al. (2002). Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA 287:337–44.
  • Kennedy JL, Koziol-White CJ, Jeffus S, et al. (2018). Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices. J Allergy Clin Immunol. 141:1887–90.
  • Kennon-McGill S, McGill MR. (2018). Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms. J Clin Transl Res, 3.
  • Kohl S, Behrens, M, Dunkel, A, et al. (2010). Amino acids and peptides activate at least five members of the human bitter taste receptor family. J Agric Food Chem 61:53–60.
  • Kreiner-Moller E, Sevelsted A, Vissing NH, et al. (2012). Infant acetaminophen use associates with early asthmatic symptoms independently of respiratory tract infections: the Copenhagen Prospective Study on Asthma in Childhood 2000 (COPSAC(2000)) cohort. J Allergy Clin Immunol 130:1434–6.
  • Lee WM. (2008). Etiologies of acute liver failure. Semin Liver Dis 28:142–52.
  • Lowe AJ, Carlin JB, Bennett CM, et al. (2010). Paracetamol use in early life and asthma: prospective birth cohort study. BMJ 341:c4616.
  • McBride JT. (2011). The association of acetaminophen and asthma prevalence and severity. Pediatrics 128:1181–5.
  • McGill MR, Jaeschke H. (2013). Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. Pharm Res 30:2174–87.
  • McGill MR, Jaeschke H. (2015). A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimide. Toxicol Mech Methods 25:589–95.
  • McGill MR, Lebofsky M, Norris HR, et al. (2013). Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications. Toxicol Appl Pharmacol 269:240–9.
  • Meyerhof W, Batram C, Kuhn C, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35:157–70.
  • Morris CR, Mauger DT, Suh JH, et al. (2018). Glutathione and arginine levels: predictors for acetaminophen-associated asthma exacerbation? J Allergy Clin Immunol 142:308–11 e9.
  • Muldrew KL, James LP, Coop L, et al. (2002). Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection. Drug Metab Dispos 30:446–51.
  • Newson RB, Shaheen SO, Chinn S, Burney PG. (2000). Paracetamol sales and atopic disease in children and adults: an ecological analysis. Eur Respir J 16:817–23.
  • Perzanowski MS, Miller RL, Tang D, et al. (2010). Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort. Thorax 65:118–23.
  • Prevention CDC. (2011). Vital signs: asthma prevalence, disease characteristics, and self management education: United States, 2001-2009. MMWR Morb Mortal Wkly Rep 60:547–52.
  • Rebordosa C, Kogevinas M, Sorensen HT, Olsen J. (2008). Pre-natal exposure to paracetamol and risk of wheezing and asthma in children: a birth cohort study. Int J Epidemiol 37:583–90.
  • Roberts DW, Bucci TJ, Benson RW, et al. (1991). Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity. Am J Pathol 138:359–71.
  • Schnabel E, Heinrich J, LISA Study Group. (2010). Respiratory tract infections and not paracetamol medication during infancy are associated with asthma development in childhood. J Allergy Clin Immunol 126:1071–3.
  • Shaheen SO, Sterne JA, Songhurst CE, Burney PG. (2000). Frequent paracetamol use and asthma in adults. Thorax 55:266–70.
  • Sheehan WJ, Mauger DT, Paul IM, et al. (2016). Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med 375:619–30.
  • Sheehan WJ, Phipatanakul W. (2016). Acetaminophen versus Ibuprofen in Mild Persistent Asthma. N Engl J Med 375:2099–100.
  • Signorello LB, McLaughlin JK, Lipworth L, et al. (2002). Confounding by indication in epidemiologic studies of commonly used analgesics. Am J Ther 9:199–205.
  • Smith GJ, Thrall RS, Cloutier MM, et al. (2016). Acetaminophen attenuates house dust mite-induced allergic airway disease in mice. J Pharmacol Exp Ther 358:569–79.
  • Soferman R, Tsivion A, Farber M, Sivan Y. (2013). The effect of a single dose of acetaminophen on airways response in children with asthma. Clin Pediatr (Phila) 52:42–8.
  • Sordillo JE, Scirica CV, Rifas-Shiman SL, et al. (2015). Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. J Allergy Clin Immunol 135:441–8.
  • Wohlsen A, Uhlig S, Martin C. (2001). Immediate allergic response in small airways. Am J Respir Crit Care Med 163:1462–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.