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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 5
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General Xenobiochemistry

Effects of dexamethasone to reverse decreased hepatic midazolam metabolism in rats with acute renal failure

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Pages 506-514 | Received 26 Jun 2019, Accepted 10 Aug 2019, Published online: 28 Aug 2019

References

  • Abdel-Razzak Z, Corcos L, Fautrel A, et al. (1995). Interleukin-1β antagonizes phenobarbital induction of several major cytochromes P450 in adult rat hepatocytes in primary culture. FEBS Lett 366:159–64.
  • Aiba T, Horiuchi M, Makita T, et al. (2006). Peritoneal dialysis alters tolbutamide pharmacokinetics in rats with experimental acute renal failure. Drug Metab Pharmacokinet 21:291–6.
  • Assenat E, Gerbal-Chaloin S, Larrey D, et al. (2004). Interleukin 1β inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. Hepatology 40:951–60.
  • Blouin RA, Bandyopadhyay AM, Chaudhary I, et al. (1993). Cytochrome P450 2B enzyme (CYP2B) induction defect following phenobarbital treatment in the fa/fa Zucker rat: molecular characterization. Arch Biochem Biophys 303:313–20.
  • Carr B, Norcross R, Fang Y, et al. (2006). Characterization of the rhesus monkey CYP3A64 enzyme: species comparisons of CYP3A substrate specificity and kinetics using baculovirus-expressed recombinant enzymes. Drug Metab Dispos 34:1703–12.
  • Cotreau MM, von Moltke LL, Beinfeld MC, et al. (2000). Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level. J Pharmacol Toxicol Methods 43:41–54.
  • De Martin S, Gabbia D, Albertin G, et al. (2014). Differential effect of liver cirrhosis on the pregnane X receptor-mediated induction of CYP3A1 and 3A2 in the rat. Drug Metab Dispos 42:1617–26.
  • Dhir RN, Shapiro BH. (2003). Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats. Proc Natl Acad Sci USA 100:15224–8.
  • Elias A, High AA, Mishra A, et al. (2014). Identification and characterization of phosphorylation sites within the pregnane X receptor protein. Biochem Pharmacol 87:360–70.
  • Gabbia D, Pozzo L, Zigiotto G, et al. (2018). Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation. PLoS One 13:e0204336.
  • Hori Y, Shimizu Y, Aiba T. (2018). Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment. Xenobiotica 48:576–83.
  • Hosseinpour F, Timsit Y, Koike C, et al. (2007). Overexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver. FEBS Lett 581:4937–42.
  • Huss JM, Kasper CB. (1998). Nuclear receptor involvement in the regulation of rat cytochrome P450 3A23 expression. J Biol Chem 273:16155–62.
  • Izuwa Y, Kusaba J, Horiuchi M, et al. (2009). Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure. Drug Metab Pharmacokinet 24:451–7.
  • Kajikawa N, Doi M, Kusaba J-i, Aiba T. (2014). Effect of carrageenan-induced acute peripheral inflammation on the pharmacokinetics and hepatic metabolism of midazolam in rats. Drug Metab Pharmacokinet 29:400–6.
  • Kanazu T, Sato N, Kadono K, et al. (2012). Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. Biopharm Drug Dispos 33:195–206.
  • Kishida T, Muto S, Hayashi M, et al. (2008). Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats. J Toxicol Sci 33:447–57.
  • Kliewer SA, Goodwin B, Willson TM. (2002). The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 23:687–702.
  • Kliewer SA, Moore JT, Wade L, et al. (1998). An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell 92:73–82.
  • Kobayashi K, Urashima K, Shimada N, et al. (2002). Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat. Biochem Pharmacol 63:889–96.
  • Krausova L, Stejskalova L, Wang H, et al. (2011). Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene. Biochem Pharmacol 82:1771–80.
  • Kusaba J, Kajikawa N, Kawasaki H, et al. (2012). Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure. Biopharm Drug Dispos 33:22–9.
  • Lang CH, Frost RA, Kumar V, et al. (2000). Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F. Am J Physiol Endocrinol Metab 279:E1029–38.
  • Li J, Wan Y, Na S, et al. (2015). Sex-dependent regulation of hepatic CYP3A by growth hormone: roles of HNF6, C/EBPα, and RXRα. Biochem Pharmacol 93:92–103.
  • Matsubara T, Kim HJ, Miyata M, et al. (2004). Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat. J Pharmacol Exp Ther 309:1282–90.
  • Naruhashi K, Sai Y, Tamai I, et al. (2002). PepT1 mRNA expression is induced by starvation and its level correlates with absorptive transport of cefadroxil longitudinally in the rat intestine. Pharm Res 19:1417–23.
  • Ourlin JC, Lasserre F, Pineau T, et al. (2003). The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity. Mol Endocrinol 17:1693–703.
  • Printsev I, Curiel D, Carraway KII. (2017). Membrane protein quantity control at the endoplasmic reticulum. J Membr Biol 250:379–92.
  • Santoh M, Sanoh S, Takagi M, et al. (2016). Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction. Sci Rep 6:21373.
  • Steineger HH, Arntsen BM, Spydevold O, et al. (1998). Gene transcription of the retinoid X receptor alpha (RXRalpha) is regulated by fatty acids and hormones in rat hepatic cells. J Lipid Res 39:744–54.
  • Sun Z, Zhang Z, Ji M, et al. (2016). BDE47 induces rat CYP3A1 by targeting the transcriptional regulation of miR-23b. Sci Rep 6:31958.
  • Wang HF, Figueiredo Pereira ME, Correia MA. (1999). Cytochrome P450 3A degradation in isolated rat hepatocytes: 26S proteasome inhibitors as probes. Arch Biochem Biophys 365:45–53.
  • Wang Y, Liao M, Hoe N, et al. (2009). A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation. J Biol Chem 284:5671–84.
  • Wonganan P, Zamboni WC, Strychor S, et al. (2009). Drug-virus interaction: effect of administration of recombinant adenoviruses on the pharmacokinetics of docetaxel in a rat model. Cancer Gene Ther 16:405–14.

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