Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats

References

• Abdel-Rahman RF, Hessin AF, Abdelbaset M, et al. (2017). Antihypertensive effects of Roselle-Olive combination in L-NAME-induced hypertensive rats. Oxid Med Cell Longev 2017:1–24.
   Web of Science ®Google Scholar
• Adaramoye OA, Nwosu IO, Farombi EO. (2012). Sub-acute effect of N(G)-nitro-l-arginine methyl-ester (L-NAME) on biochemical indices in rats: protective effects of Kolaviron and extract of Curcuma longa L. Pharmacognosy Res 4:127–33.
   PubMedGoogle Scholar
• Ahad A, Al-Saleh AA, Al-Mohizea AM, Al-Jenoobi FI, et al. (2017). Pharmacodynamic study of eprosartan mesylate-loaded transfersomes Carbopol((R)) gel under Dermaroller((R)) on rats with methyl prednisolone acetate-induced hypertension. Biomed Pharmacother 89:177–84.
   PubMed Web of Science ®Google Scholar
• Ahad A, Aqil M, Kohli K, et al. (2016). Nano vesicular lipid carriers of angiotensin II receptor blocker: Anti-hypertensive and skin toxicity study in focus. Artif Cells Nanomed Biotechnol 44:1002–7.
   PubMed Web of Science ®Google Scholar
• Ahad A, Raish M, Ahmad A, et al. (2018a). Eprosartan mesylate loaded bilosomes as potential nano-carriers against diabetic nephropathy in streptozotocin-induced diabetic rats. Eur J Pharm Sci 111:409–17.
   PubMed Web of Science ®Google Scholar
• Ahad A, Raish M, Al-Jenoobi FI, Al-Mohizea AM. (2018b). Sorbitane monostearate and cholesterol based niosomes for oral delivery of telmisartan. Curr Drug Deliv 15:260–6.
   PubMed Web of Science ®Google Scholar
• Ajay M, Chai HJ, Mustafa AM, et al. (2007). Mechanisms of the anti-hypertensive effect of Hibiscus sabdariffa L. calyces. J Ethnopharmacol 109:388–93.
   PubMed Web of Science ®Google Scholar
• Alam MA, Abou Obaid NI, Ibrahim MA, et al. (2019). A validated ultra-performance liquid chromatography tandem triple quadrupole mass spectrometric method for fast determination of losartan in rabbit plasma. J Chromatogr Sci 57:323–30.
   PubMed Web of Science ®Google Scholar
• Alarcon-Alonso J, Zamilpa A, Aguilar FA, et al. (2012). Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract. J Ethnopharmacol 139:751–6.
   PubMed Web of Science ®Google Scholar
• Ali BH, Al Wabel N, Blunden G. (2005). Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytother Res 19:369–75.
   PubMed Web of Science ®Google Scholar
• Ali BH, Blunden G, Tanira MO, Nemmar A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol 46:409–20.
   PubMed Web of Science ®Google Scholar
• Alqasoumi S, Al-Dosari M, Al-Sohaibani M, et al. (2010). Gastric ulcer protective activity of Hibiscus sabdariffa: an experimental, biochemical and histological study. Clin Exp Med J 4:115–27.
   Google Scholar
• Bernatova I. (2014). Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence? Biomed Res Int 2014:1–14.
   Web of Science ®Google Scholar
• Bernatova I, Pechanova O, Simko F. (1999). Effect of captopril in L-NAME-induced hypertension on the rat myocardium, aorta, brain and kidney. Exp Physiol 84:1095–105.
   PubMed Web of Science ®Google Scholar
• Biancardi VC, Bergamaschi CT, Lopes OU, Campos RR. (2007). Sympathetic activation in rats with L-NAME-induced hypertension. Braz J Med Biol Res 40:401–8.
   PubMed Web of Science ®Google Scholar
• Da-Costa-Rocha I, Bonnlaender B, Sievers H, et al. (2014). Hibiscus sabdariffa L. – a phytochemical and pharmacological review. Food Chem 165:424–43.
   PubMed Web of Science ®Google Scholar
• Diogo LN, Faustino IV, Afonso RA, et al. (2015). Voluntary oral administration of losartan in rats. J Am Assoc Lab Anim Sci 54:549–56.
   PubMed Web of Science ®Google Scholar
• El-Hady AM, Gabr NM, Abbas MA. (2015). Effect of red Hibiscus aqueous extract on alloxan-induced diabetes in adult male albino rats. Al Azhar Med J 44:237–45.
   Google Scholar
• Ghayur MN, Gilani AH. (2005). Ginger lowers blood pressure through blockade of voltage-dependent calcium channels. J Cardiovasc Pharmacol 45:74–80.
   PubMed Web of Science ®Google Scholar
• Ghayur MN, Gilani AH, Afridi MB, Houghton PJ. (2005). Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul Pharmacol 43:234–41.
   PubMed Web of Science ®Google Scholar
• Herrera-Arellano A, Flores-Romero S, Chávez-Soto MA, Tortoriello J. (2004). Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine 11:375–82.
   PubMed Web of Science ®Google Scholar
• Herrera-Arellano A, Miranda-Sanchez J, Avila-Castro P, et al. (2006). Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension: a randomized, double-blind, lisinopril-controlled clinical trial. Planta Med 73:6–12.
   Web of Science ®Google Scholar
• Hopkins AL, Lamm MG, Funk JL, Ritenbaugh C. (2013). Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies. Fitoterapia 85:84–94.
   PubMed Web of Science ®Google Scholar
• Inuwa I, Ali BH, Al-Lawati I, et al. (2012). Long-term ingestion of Hibiscus sabdariffa calyx extract enhances myocardial capillarization in the spontaneously hypertensive rat. Exp Biol Med (Maywood) 237:563–9.
   PubMed Web of Science ®Google Scholar
• Johnson SS, Oyelola FT, Ari T, Juho H. (2013). In vitro inhibitory activities of the extract of Hibiscus sabdariffa L. (family Malvaceae) on selected cytochrome P450 isoforms. Afr J Tradit Complement Altern Med 10:533–40.
   PubMedGoogle Scholar
• Kim IS, Kim SY, Yoo HH. (2012). Effects of an aqueous-ethanolic extract of ginger on cytochrome P450 enzyme-mediated drug metabolism. Pharmazie 67:1007–9.
   PubMed Web of Science ®Google Scholar
• Kimura Y, Ito H, Hatano T. (2010). Effects of mace and nutmeg on human cytochrome P450 3A4 and 2C9 activity. Biol Pharm Bull 33:1977–82.
   PubMed Web of Science ®Google Scholar
• Kohzuki M, Yasujima M, Yoshida K, et al. (1994). Antihypertensive and antiproteinuretic losartan in spontaneously hypertensive chronic renal failure. Hypertens Res 17:173–8.
   Google Scholar
• Kopincova J, Puzserova A, Bernatova I. (2012). L-NAME in the cardiovascular system – nitric oxide synthase activator? Pharmacol Rep 64:511–20.
   PubMed Web of Science ®Google Scholar
• Leal DT, Fontes GG, Villa JKD, et al. (2019). Zingiber officinale formulation reduces hepatic injury and weight gain in rats fed an unhealthy diet. An Acad Bras Cienc 91:e20180975.
   PubMed Web of Science ®Google Scholar
• Li H, Liu L, Xie L, et al. (2016). Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol 54:2886–94.
   PubMed Web of Science ®Google Scholar
• Li M, Chen PZ, Yue QX, et al. (2013). Pungent ginger components modulates human cytochrome P450 enzymes in vitro. Acta Pharmacol Sin 34:1237–42.
   PubMed Web of Science ®Google Scholar
• Mata-Greenwood E, Chen DB. (2008). Racial differences in nitric oxide-dependent vasorelaxation. Reprod Sci 15:9–25.
   PubMed Web of Science ®Google Scholar
• McKay DL, Chen CY, Saltzman E, Blumberg JB. (2010). Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr 140:298–303.
   PubMed Web of Science ®Google Scholar
• Nabekura T, Kamiyama S, Kitagawa S. (2005). Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem Biophys Res Commun 327:866–70.
   PubMed Web of Science ®Google Scholar
• Ngamjarus C, Pattanittum P, Somboonporn C. (2010). Roselle for hypertension in adults. Cochrane Database Syst Rev 1:CD007894.
   Google Scholar
• Odigie IP, Ettarh RR, Adigun SA. (2003). Chronic administration of aqueous extract of Hibiscus sabdariffa attenuates hypertension and reverses cardiac hypertrophy in 2K-1C hypertensive rats. J Ethnopharmacol 86:181–5.
   PubMed Web of Science ®Google Scholar
• Oga EF, Sekine S, Shitara Y, Horie T. (2016). Pharmacokinetic herb-drug interactions: insight into mechanisms and consequences. Eur J Drug Metab Pharmacokinet 41:93–108.
   PubMed Web of Science ®Google Scholar
• Ojulari LS, Olatubosun OT, Okesina KB, et al. (2014). The effect of zingiber officinale (Ginger) extract on blood pressure and heart rate in healthy humans. IOSR J Dental Med Sci 13:76–8.
   Google Scholar
• Ondieki G, Nyagblordzro M, Kikete S, et al. (2017). Cytochrome P450 and P-glycoprotein-mediated interactions involving African herbs indicated for common noncommunicable diseases. Evid Based Complement Alternat Med 2017:1–18.
   Web of Science ®Google Scholar
• Pandit S, Mukherjee PK, Mukherjee K, et al. (2012). Cytochrome P450 inhibitory potential of selected Indian spices – possible food drug interaction. Food Res Int 45:69–74.
   Web of Science ®Google Scholar
• Riaz G, Chopra R. (2018). A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L. Biomed Pharmacother 102:575–86.
   PubMed Web of Science ®Google Scholar
• Ribeiro MO, Antunes E, de Nucci G, et al. (1992). Chronic inhibition of nitric oxide synthesis: a new model of arterial hypertension. Hypertension 20:298–303.
   PubMed Web of Science ®Google Scholar
• Rincon J, Correia D, Arcaya JL, et al. (2015). Role of angiotensin II type 1 receptor on renal NAD(P)H oxidase, oxidative stress and inflammation in nitric oxide inhibition induced-hypertension. Life Sci 124:81–90.
   PubMed Web of Science ®Google Scholar
• Rossoni G, Manfredi B, Gennaro Colonna V, et al. (2009). Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat. Br J Pharmacol 150:567–76.
   Web of Science ®Google Scholar
• Sarr M, Ngom S, Kane MO, et al. (2009). In vitro vasorelaxation mechanisms of bioactive compounds extracted from Hibiscus sabdariffa on rat thoracic aorta. Nutr Metab (Lond) 6:45.
   PubMed Web of Science ®Google Scholar
• Sharan PS, Kumar VN, Bhupendra S, Karunakaran G. (2011). Antihypertensive effect of methanolic extract of Passiflora nepalensis. Rev. bras. farmacogn 21:187–9.
   Google Scholar
• Shelly TE, McInnis DO, Pahio E, Edu J. (2004). Aromatherapy in the Mediterranean fruit fly (Diptera: Tephritidae): sterile males exposed to ginger root oil in prerelease storage boxes display increased mating competitiveness in field-cage trials. J Econ Entomol 97:846–53.
   PubMed Web of Science ®Google Scholar
• Showande SJ, Adegbolagun OM, Igbinoba SI, Fakeye TO. (2017). In vivo pharmacodynamic and pharmacokinetic interactions of Hibiscus sabdariffa calyces extracts with simvastatin. J Clin Pharm Ther 42:695–703.
   PubMed Web of Science ®Google Scholar
• Sung JH, Jo YS, Kim SJ, Ryu JS, et al. (2013). Effect of lutein on L-NAME-induced hypertensive rats. Korean J Physiol Pharmacol 17:339–45.
   PubMed Web of Science ®Google Scholar
• Tata CM, Sewani-Rusike CR, Oyedeji OO, et al. (2019). Antihypertensive effects of the hydro-ethanol extract of Senecio serratuloides DC in rats. BMC Complement Altern Med 19:52.
   PubMed Web of Science ®Google Scholar
• Varshney E, Saha N, Tandon M, et al. (2013). Genotype-phenotype correlation of cytochrome P450 2C9 polymorphism in Indian National Capital Region. Eur J Drug Metab Pharmacokinet 38:275–82.
   PubMed Web of Science ®Google Scholar
• Wahabi HA, Alansary LA, Al-Sabban AH, Glasziuo P. (2010). The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: a systematic review. Phytomedicine 17:83–6.
   PubMed Web of Science ®Google Scholar
• Yang SH, Choi JS, Choi DH. (2011). Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors. Pharmacology 88:1–9.
   PubMed Web of Science ®Google Scholar
• Yusuf AA, Lawal B, Abubakar AN, et al. (2018). In-vitro antioxidants, antimicrobial and toxicological evaluation of Nigerian Zingiber officinale. Clin Phytosci 4:12.
   Google Scholar
• Zambrano S, Blanca AJ, Ruiz-Armenta MV, et al. (2014). L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-gamma. Am J Hypertens 27:460–70.
   PubMed Web of Science ®Google Scholar