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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 10
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General Xenobiochemistry

Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver

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Pages 1139-1148 | Received 09 Mar 2020, Accepted 31 Mar 2020, Published online: 16 Apr 2020

References

  • Anzenbacher P, Anzenbacherová E. (2001). Cytochromes P450 and metabolism of xenobiotics. Cellular and Molecular Life Sciences 58:737–47. 
  • Aziz MH, Chen X, Zhang Q, et al. (2015). Suppressing NRIP1 inhibits growth of breast cancer cells in vitro and in vivo. Oncotarget 6:39714.
  • Balsalobre A, Damiola F, Schibler U. (1998). A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93:929–37.
  • Bass J, Takahashi JS. (2010). Circadian integration of metabolism and energetics. Science 330:1349–54.
  • Beigneux AP, Moser AH, Shigenaga JK, et al. (2002). Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. Biochem Biophys Res Commun 293:145–9.
  • Bozek K, Relógio A, Kielbasa SM, et al. (2009). Regulation of clock-controlled genes in mammals. PloS One 4:e4882.
  • Buhr ED, Takahashi JS. (2013). Molecular components of the Mammalian circadian clock. In: Barrett JE, ed. Circadian clocks. Berlin: Springer, 3–27.
  • Chen M, Guan B, Xu H, et al. (2019). The molecular mechanism regulating diurnal rhythm of flavin-containing monooxygenase 5 in mouse liver. Drug Metabol Dispos 47:1333–42.
  • Curtis AM, Bellet MM, Sassone-Corsi P, O’Neill LA. (2014). Circadian clock proteins and immunity. Immunity 40:178–86.
  • Danielson PB. (2002). The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metabol 3:561–97.
  • De Kanter R, Olinga P, De Jager MH, et al. (1999). Organ slices as an in vitro test system for drug metabolism in human liver, lung and kidney. Toxicol in Vitro 13:737–44.
  • Deng J, Guo L, Wu B. (2018). Circadian regulation of hepatic cytochrome P450 2a5 by peroxisome proliferator-activated receptor γ. Drug Metabol Dispos 46:1538–45. 
  • Ekins S, Bravi G, Ring BJ, et al. (1999). Three-dimensional quantitative structure activity relationship analyses of substrates for CYP2B6. J Pharmacol Exp Ther 288:21–9.
  • Ekins S, Vandenbranden M, Ring BJ, et al. (1998). Further characterization of the expression in liver and catalytic activity of CYP2B6. J Pharmacol Exp Therap 286:1253–9.
  • Furge LL, Guengerich FP. (2006). Cytochrome P450 enzymes in drug metabolism and chemical toxicology: an introduction. Biochem Mol Biol Educ 34:66–74.
  • Gachon F, Olela F F, Schaad O, et al. (2006). The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metabol 4:25–36. 
  • Glass CK, Rosenfeld MG. (2000). The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14:121–41.
  • Guo L, Yu F, Zhang T, Wu B. (2018). The clock protein bmal1 regulates circadian expression and activity of sulfotransferase 1a1 in mice. Drug Metab Dispos 46:1403–10.
  • Hallberg M, Morganstein DL, Kiskinis E, et al. (2008). A functional interaction between RIP140 and PGC-1α regulates the expression of the lipid droplet protein CIDEA. Mol Cell Biol 28:6785–95.
  • Hardwick JP, Gonzalez FJ, Kasper CB. (1983). Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital. J Biol Chem 258:8081–5.
  • Harnish DC, Evans MJ, Scicchitano MS, et al. (1998). Estrogen regulation of the apolipoprotein AI gene promoter through transcription cofactor sharing. J Biol Chem 273:9270–8. 
  • Herzog B, Hallberg M, Seth A, et al. (2007). The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor. Mol Endocrinol 21:2687–97. 
  • Ho PC, Tsui YC, Feng X, et al. (2012). NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance. Nat Immunol 13:379–86.
  • Hollenberg PF. (2002). Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes. Drug Metabol Rev 34:17–35. 
  • Honkakoski P, Negishi M. (1997). Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene. J Biol Chem 272:14943–9.
  • Honkakoski P, Sueyoshi T, Negishi M. (2003). Drug-activated nuclear receptors CAR and PXR. Ann Med 35:172–82. 
  • Honkakoski P, Zelko I, Sueyoshi T, Negishi M. (1998). The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol Cell Biol 18:5652–8.
  • Kawase A, Ohgami T, Yoshida I, et al. (2013). Diurnal variation of nuclear receptors in mice with or without fasting. Pharmacol Pharm 4:240–3. 
  • LinY, Wang S, Zhou Z, et al. (2019). Bmal1 regulatescircadian expression of cytochrome P450 3a11 and drug metabolism in mice. Communicationsbiology 2:1–11.
  • Motomura Y, Kitamura H, Hijikata A, et al. (2011). The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 12:450–9.
  • Nagoshi E, Brown SA, Dibner C, et al. (2005). Circadian gene expression in cultured cells. In: Michael WY, ed. Methods in enzymology (Vol. 393). New York: Academic Press, 543–57.
  • Nautiyal J. (2017). Transcriptional coregulator RIP140: an essential regulator of physiology. J Mol Endocrinol 58:R147–R158.
  • Nebert DW, Russell DW. (2002). Clinical importance of the cytochromes P450. The Lancet 360:1155–62.
  • O’Malley BW. (2007). Coregulators: from whence came these “master genes”. Mol Endocrinol 21:1009–13.
  • Partch CL, Green CB, Takahashi JS. (2014). Molecular architecture of the mammalian circadian clock. Trends Cell Biol 24:90–9.
  • Poliandri AH, Gamsby JJ, Christian M, et al. (2011). Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140). J Biol Rhythms 26:187–99.
  • Sueyoshi T, Kawamoto T, Zelko I, et al. (1999). The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J Biol Chem 274:6043–6.
  • Sueyoshi T, Negishi M. (2001). Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annual Rev Pharmacol Toxicol 41:123–43.
  • Timsit YE, Negishi M. (2007). CAR and PXR: the xenobiotic-sensing receptors. Steroids 72:231–46.
  • Tong Y, Zeng P, Zhang T, et al. (2019). The transcription factor E4bp4 regulates the expression and activity of Cyp3a11 in mice. Biochem Pharmacol 163:215–24.
  • Wang S, Lin Y, Yuan X, et al. (2018). REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis. Nat Commun 9:4246.
  • Wang S, Lin Y, Zhou Z, et al. (2019). Circadian clock gene bmal1 regulates bilirubin detoxification: a potential mechanism of feedback control of hyperbilirubinemia. Theranostics 9:5122–33.
  • Wu J C, Merlino G, Fausto N. (1994). Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proceedings of the National Academy of Sciences 91:674–8.
  • Yu F, Zhang T, Zhou C, et al. (2019). The Circadian Clock Gene Bmal1 controls intestinal exporter MRP2 and drug disposition. Theranostics 9:2754–67.
  • Zhang T, Yu F, Guo L, et al. (2018). Small heterodimer partner regulates circadian cytochromes p450 and drug-induced hepatotoxicity. Theranostics 8:5246–58.
  • Zhao M, Zhao H, Deng J, et al. (2019). Role of the CLOCK protein in liver detoxification. Br J Pharmacol 176:4639–52.
  • Zhou Z, Lin Y, Gao L, et al. (2019). Cyp3a11 metabolism-based chronotoxicity of brucine in mice. Toxicol Lett 313:188–95.
  • Zschiedrich I, Hardeland U, Krones-Herzig A, et al. (2008). Coactivator function of RIP140 for NFκB/RelA-dependent cytokine gene expression. Blood 112:264–76. 

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