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Xenobiotica
the fate of foreign compounds in biological systems
Volume 50, 2020 - Issue 12
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General Xenobiochemistry

Characterization of hydrocoptisonine metabolites in human liver microsomes using a high-resolution quadrupole-orbitrap mass spectrometer

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Pages 1423-1433 | Received 25 May 2020, Accepted 07 Jul 2020, Published online: 20 Jul 2020

References

  • Antolino-Lobo I, Meulenbelt J, Nijmeijer SM, et al. (2010). Differential roles of phase I and phase II enzymes in 3,4-methylendioxymethamphetamine-induced cytotoxicity. Drug Metab Dispos 38:1105–12.
  • Cao TQ, Ngo QT, Seong SH, et al. (2018). Cholinesterase inhibitory alkaloids from the rhizomes of Coptis chinensis. Bioorg Chem 77:625–32.
  • Cho PJ, Kim JH, Lee HS, et al. (2019). Identification of specific UGT1A9-mediated glucuronidation of licoricidin in human liver microsomes. Biopharm Drug Dispos 40:94–8.
  • Commission CP. (2015). Pharmacopeia of the People's Republic of China (Version 2015). Beijing, China: China Medical Science Press.
  • Guengerich FP. (2018). Mechanisms of cytochrome P450-catalyzed oxidations. ACS Catalysis 8:10964–76.
  • Hwang J-M, Kuo H-C, Tseng T-H, et al. (2006). Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells. Arch Toxicol 80:62–73.
  • Lee SK, Jeong HG, Lee ES, Jeong TC. (2007). Metabolism of FPP-3, an anti-inflammatory propenone compound, in rat by liquid chromatography-electrospray ionization tandem mass spectrometry. Biol Pharm Bull 30:967–71.
  • Lee JW, Kang YJ, Choi HK, Yoon YG. (2018). Fractionated Coptis chinensis extract and its bioactive component suppress Propionibacterium acnes-stimulated inflammation in human keratinocytes. J Microbiol Biotechn 28:839–48.
  • Lee S, Lee J, Jahng Y, et al. (2013). Characterization of in vitro metabolites of luotonin A in human liver microsomes using electrospray/tandem mass spectrometry. Xenobiotica 43:527–33.
  • Lee SK, Lee J, Lee ES, et al. (2004). Characterization of in vitro metabolites of rutaecarpine in rat liver microsomes using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 18:1073–80.
  • Lin J, Sahakian DC, De Morais S, et al. (2003). The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery. Curr Top Med Chem 3:1125–54.
  • Liu Y, She M, Wu Z, Dai R. (2011). The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. J Enzyme Inhib Med Chem 26:386–93.
  • Meyer MR, Peters FT, Maurer HH. (2008). The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxy-methamphetamine and its enantiomers. Drug Metab Dispos 36:2345–54.
  • Miao Q, Zhao Y-Y, Miao P-P, et al. (2015). Proteomics approach to analyze protein profiling related with ADME/Tox in rat treated with Scutellariae Radix and Coptidis Rhizoma as well as their compatibility. J Ethnopharmacol 173:241–50.
  • Radominska-Pandya A, Czernik PJ, Little JM, et al. (1999). Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev 31:817–99.
  • Shrestha R, Cho PJ, Paudel S, et al. (2018). Exploring the metabolism of loxoprofen in liver microsomes: the role of cytochrome P450 and UDP-glucuronosyltransferase in its biotransformation. Pharmaceutics 10:112.
  • Shrestha R, Jo JJ, Lee D, et al. (2019). Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry. Xenobiotica 49:577–83.
  • Song M, Lee D, Kim S, et al. (2014). Identification of metabolites of N-(5-benzoyl-2-(4-(2-methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide including CYP3A4-mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass. Drug Metab Dispos 42:1252–60.
  • Yu H-H, Kim K-J, Cha J-D, et al. (2005). Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. J Med Food 8:454–61.

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