Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 51, 2021 - Issue 3
69
Views
3
CrossRef citations to date
0
Altmetric
Clinical Pharmacokinetics and Metabolism

Comparative HPLC-MS/MS-based pharmacokinetic studies of multiple diterpenoid alkaloids following the administration of Zhenwu Tang and Radix Aconiti Lateralis Praeparata extracts to rats

ORCID Icon, ORCID Icon, ORCID Icon, , ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , ORCID Icon & ORCID Icon show all
Pages 345-354 | Received 23 Oct 2020, Accepted 15 Dec 2020, Published online: 05 Jan 2021

References

  • Cheng, C.-W., et al., CONSORT-CHM Formulas 2017 Group, 2017. CONSORT Extension for Chinese Herbal Medicine Formulas 2017: recommendations, explanation, and elaboration (Traditional Chinese Version). Annals of internal medicine, 167 (2), W7–W20.
  • Chinese Pharmacopoeia Commission, 2020. Pharmacopoeia of People’s Republic of China. 11th ed. Beijing, China.
  • Cyranoski, D.J., 2018. Why Chinese medicine is heading for clinics around the world. Nature, 561 (7724), 448–450.
  • Gao, W., et al., 2018. Targeted profiling and relative quantification of benzoyl diterpene alkaloids in Aconitum roots by using LC-MS/MS with precursor ion scan. Journal of separation science, 41 (18), 3515–3526.
  • Guo, Q., et al., 2018. C19-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities. Acta pharmaceutica sinica. B, 8 (3), 409–419.
  • He, F., et al., 2017. Simultaneous quantification of nine aconitum alkaloids in Aconiti Lateralis Radix Praeparata and related products using UHPLC-QQQ-MS/MS. Scientific reports, 7 (1), 13023.
  • He, Y., et al., 2020. Potential synergic mechanism of Wutou-Gancao herb-pair by inhibiting efflux transporter P-glycoprotein. Journal of pharmaceutical analysis, 10 (2), 178–186.
  • Hong, L.-L., et al., 2020. Evaluation of Zhenwu decoction effects on CYP450 enzymes in rats using a cocktail method by UPLC-MS/MS. Biomed research international, 2020, 4816209.
  • Hu, F., et al., 2015. UPLC-MS/MS determination and gender-related pharmacokinetic study of five active ingredients in rat plasma after oral administration of Eucommia cortex extract. Journal of ethnopharmacology, 169, 145–155.
  • Huang, L., et al., 2018. TCMID 2.0: a comprehensive resource for TCM. "Agricultural Health and Environment" Omics Big Data Integration Bioinformatics Symposium, 46, D1117–D1120.
  • La, L., et al., 2018. Zhen-wu-tang ameliorates adenine-induced chronic renal failure in rats: regulation of the canonical Wnt4/beta-catenin signaling in the kidneys. Journal of ethnopharmacology, 219, 81–90.
  • Lei, M., et al., 2014. Comparative pharmacokinetics study of a kaurane diterpenoid after oral administration of monomer and Siegesbeckiae pubescens Makino extract to rats. Biomedical chromatography: BMC, 28 (5), 673–679.
  • Li, H.Q., et al., 2019. Optimization of the traditional processing method for precision detoxification of CaoWu through biomimetic linking kinetics and human toxicokinetics of aconitine as toxic target marker. Journal of ethnopharmacology, 242, 112053.
  • Li, H., et al., 2016. Case reports of aconite poisoning in mainland China from 2004 to 2015: a retrospective analysis. Journal of forensic and legal medicine, 42, 68–73.
  • Liang, C., et al., 2019. Zhen-wu-tang attenuates adriamycin-induced nephropathy via regulating AQP2 and miR-92b. Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie, 109, 1296–1305.
  • Liang, X., et al., 2020. Identification of active compounds of Mahuang Fuzi Xixin decoction and their mechanisms of action by LC-MS/MS and network pharmacology. Evidence-based complementary and alternative medicine, 2020, 3812180.
  • Liu, B., et al., 2019. Zhen-wu-tang ameliorates membranous nephropathy rats through inhibiting NF-κB pathway and NLRP3 inflammasome. Phytomedicine: international journal of phytotherapy and phytopharmacology, 59, 152913.
  • Liu, M., et al., 2020. Synergistic effect of Aconiti Lateralis Radix Praeparata water-soluble alkaloids and Ginseng Radix et Rhizoma total ginsenosides compatibility on acute heart failure rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1137, 121935.
  • Miao, L.-L., et al., 2019. Aconitum carmichaelii discrimination of the geographical origin of the lateral roots of using the fingerprint. Molecules, 24 (22), 4124.
  • Regitz-Zagrosek, V., 2014. [Sex and gender differences in pharmacotherapy]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 57 (9), 1067–1073.
  • Singhuber, J., et al., 2009. Aconitum in traditional Chinese medicine: a valuable drug or an unpredictable risk? Journal of ethnopharmacology, 126 (1), 18–30.
  • Tang, Q., Wang, Y., and Li, K., 2018. Zhenwu decoction for chronic heart failure: protocol for a systematic review and meta-analysis. Medicine, 97 (29), e11559.
  • Wang, M., et al., 2020b. Identification of hub genes in protective effect of astragaloside IV on aconitine-induced cardiac damage in zebrafish based on bioinformatics analysis. Frontiers in pharmacology, 11, 957.
  • Wang, X., Lin, Y., and Zheng, Y., 2020a. Antitumor effects of aconitine in A2780 cells via estrogen receptor β-mediated apoptosis, DNA damage and migration. Molecular medicine reports, 22, 2318–2328.
  • Wu, J., et al., 2016. Zhen-wu-tang attenuates cationic bovine serum albumin-induced inflammatory response in membranous glomerulonephritis rat through inhibiting AGEs/RAGE/NF-κB pathway activation. International immunopharmacology, 33, 33–41.
  • Wu, J.-J., et al., 2018. A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine. Phytomedicine: international journal of phytotherapy and phytopharmacology, 44, 187–203.
  • Xu, H., et al., 2013. Gender-dependent pharmacokinetics of lignans in rats after single and multiple oral administration of Schisandra chinensis extract. Journal of ethnopharmacology, 147 (1), 224–231.
  • Xu, Y., et al., 2017. Sensitive UHPLC-MS/MS quantitation and pharmacokinetic comparisons of multiple alkaloids from Fuzi- Beimu and single herb aqueous extracts following oral delivery in rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1058, 24–31.
  • Xue, T.-H., 2016. Synergy in traditional Chinese medicine. The Lancet. Oncology, 17 (2), e39.
  • Yu, B., Cao, Y., and Xiong, Y.-K., 2015. Pharmacokinetics of aconitine-type alkaloids after oral administration of Fuzi (Aconiti Lateralis Radix Praeparata) in rats with chronic heart failure by microdialysis and ultra-high performance liquid chromatography-tandem mass spectrometry. Journal of ethnopharmacology, 165, 173–179.
  • Zhang, Q., et al., 2014. Pharmacokinetics difference of multiple active constituents from decoction and maceration of Fuzi Xiexin Tang after oral administration in rat by UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis, 92, 35–46.
  • Zhang, Y., et al., 2020a. Improved biosafety and transdermal delivery of aconitine via diethylene glycol monoethyl ether-mediated microemulsion assisted with microneedles. Pharmaceutics, 12 (2), 163.
  • Zhang, Y., et al., 2020b. Pharmacokinetics and tissue distribution of eighteen major alkaloids of Aconitum carmichaelii in rats by UHPLC-QQQ-MS. Journal of pharmaceutical and biomedical analysis, 185, 113226.
  • Zhao, Z.-H., et al., 2016. [Establishment of biological assess for quality control of Fuzi based on determination of premature ventricular contractions in rats]. Zhongguo Zhong Yao Za Zhi, 41, 3814–3820.
  • Zhou, G., et al., 2015. A review on phytochemistry and pharmacological activities of the processed lateral root of Aconitum carmichaelii Debeaux. Journal of ethnopharmacology, 160, 173–193.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.