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Xenobiotica
the fate of foreign compounds in biological systems
Volume 51, 2021 - Issue 9
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General Xenobiochemistry

Empirical and theoretical approaches for the prediction of human hepatic clearance using chimeric mice with humanised liver: the use of physiologically based scaling, a novel solution for potential overprediction due to coexisting mouse metabolism

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Pages 983-994 | Received 20 May 2021, Accepted 29 Jun 2021, Published online: 15 Jul 2021

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