Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 6
Submit an article Journal homepage
89
Views
1
CrossRef citations to date
0
Altmetric
Clinical Pharmacokinetics and Metabolism

Development and validation of a highly sensitive and selective LC-MS/MS method for the determination of 15-hydroxylubiprostone in human plasma: application to a pharmacokinetic study in healthy Chinese volunteers

Xianjing Lia Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, School of Pharmacy, China Pharmaceutical University, Nanjing, China;b Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, ChinaView further author information
,
Haitao Yuc Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd, Nanjing, ChinaView further author information
,
Wenjing Guoa Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, School of Pharmacy, China Pharmaceutical University, Nanjing, China;b Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, ChinaView further author information
,
Minlu Chengd Nanjing Clinical Tech. Laboratories Inc, Nanjing, ChinaView further author information
,
Qinxin Songa Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, School of Pharmacy, China Pharmaceutical University, Nanjing, China;b Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, ChinaCorrespondence[email protected]
View further author information
&
Li Dinga Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, School of Pharmacy, China Pharmaceutical University, Nanjing, China;b Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China;d Nanjing Clinical Tech. Laboratories Inc, Nanjing, ChinaCorrespondence[email protected]
View further author information
Pages 567-574 | Received 29 Jul 2022, Accepted 08 Sep 2022, Published online: 27 Sep 2022

References

  • Alammar N, Stein E. 2019. Irritable bowel syndrome: what treatments really work. Med Clin North Am. 103(1):137–152.
  • Black CJ, Ford AC. 2018. Chronic idiopathic constipation in adults: epidemiology, pathophysiology, diagnosis and clinical management. Med J Aust. 209(2):86–91.
  • Catalan MA, Julio-Kalajzic F, Niemeyer MI, Cid LP, Sepulveda FV. 2020. Short chain fatty acids effect on chloride channel ClC-2 as a possible mechanism for lubiprostone intestinal action. Cells. 9(8):1781.
  • Cuppoletti J, Malinowska DH, Tewari KP, Li QJ, Sherry AM, Patchen ML, Ueno R. 2004. SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents. Am J Physiol Cell Physiol. 287(5):C1173–83.
  • Drossman DA, Chey WD, Johanson JF, Fass R, Scott C, Panas R, Ueno R. 2009. Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome–results of two randomized, placebo-controlled studies. Aliment Pharmacol Ther. 29(3):329–341.
  • Emmanuel A, Mattace-Raso F, Neri MC, Petersen KU, Rey E, Rogers J. 2017. Constipation in older people: a consensus statement. Int J Clin Pract. 71(1):e12920.
  • Food and Drug Administration. 2006. Clinical pharmacology biopharmaceutics review(s) of AMITIZA. Food and Drug Administration. [accessed 8 September 2021]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2006/021908s000_Amitiza_BIOPHARMR.pdf.
  • Food and Drug Administration. 2015. Draft guidance on lubiprostone. Food and Drug Administration. [accessed 2021 September 8]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/psg/Lubiprostone_draft_Oral%20cap_RLD%2021908_RC07-15.pdf
  • Food and Drug Administration. 2018. Bioanalytical method validation guidance for industry. Food and Drug Administration. [accessed 2021 September 9]. Available from: https://www.fda.gov/media/70858/download
  • Food and Drug Administration. 2020. AMITIZATM (lubiprostone) soft gelatin capsules. Food and Drug Administration. [accessed 2021 September 8]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021908s018lbl.pdf
  • Forootan M, Bagheri N, Darvishi M. 2018. Chronic constipation: a review of literature. Medicine (Baltimore). 97(20):e10631.
  • Ishiyama Y, Hoshide S, Mizuno H, Kario K. 2019. Constipation-induced pressor effects as triggers for cardiovascular events. J Clin Hypertens (Greenwich). 21(3):421–425.
  • Jamal MM, Adams AB, Jansen JP, Webster LR. 2015. A randomized, placebo-controlled trial of lubiprostone for opioid-induced constipation in chronic noncancer pain. Am J Gastroenterol. 110(5):725–732.
  • Lembo AJ, Johanson JF, Parkman HP, Rao SS, Miner PB, Jr., Ueno R. 2011. Long-term safety and effectiveness of lubiprostone, a chloride channel (ClC-2) activator, in patients with chronic idiopathic constipation. Dig Dis Sci. 56(9):2639–2645.
  • Mei A, Venkatasubramanian J, Boonkaewwan C, Ganesan N, Syed A, Benya RV, Rao MC. 2011. Lubiprostone activates Cl secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84. Dig Dis Sci. 56(2):339–351.
  • Norimatsu Y, Moran AR, MacDonald KD. 2012. Lubiprostone activates CFTR, but not ClC-2, via the prostaglandin receptor (EP(4)). Biochem Biophys Res Commun. 426(3):374–379.
  • Pinto GA, Pastre KI, Bellorio KB, de Souza Teixeira L, de Souza WC, de Abreu FC, de Santana E, Pianetti GA, Cesar IC. 2014. An improved LC-MS/MS method for quantitation of indapamide in whole blood: application for a bioequivalence study. Biomed Chromatogr. 28(9):1212–1218.
  • Rezk MR, Badr KA. 2021. Determination of amlodipine, indapamide and perindopril in human plasma by a novel LC-MS/MS method: application to a bioequivalence study. Biomed Chromatogr. 35(5):e5048.
  • Sumida K, Molnar MZ, Potukuchi PK, Thomas F, Lu JL, Yamagata K, Kalantar-Zadeh K, Kovesdy CP. 2019. Constipation and risk of death and cardiovascular events. Atherosclerosis. 281:114–120.
  • Sundboll J, Thygesen SK, Veres K, Liao D, Zhao J, Gregersen H, Sorensen HT. 2019. Risk of cancer in patients with constipation. Clin Epidemiol. 11:299–310.
  • Tao Y, Wang S, Wang L, Song M, Hang T. 2018. Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application. J Pharm Anal. 8(5):333–340.
  • Tvistholm N, Munch L, Danielsen AK. 2017. Constipation is casting a shadow over everyday life - a systematic review on older people’s experience of living with constipation. J Clin Nurs. 26(7–8):902–914.
  • Verkuijl SJ, Meinds RJ, Trzpis M, Broens PMA. 2020. The influence of demographic characteristics on constipation symptoms: a detailed overview. BMC Gastroenterol. 20(1):168.
  • Viscusi ER. 2019. Clinical overview and considerations for the management of opioid-induced constipation in patients with chronic noncancer pain. Clin J Pain. 35(2):174–188.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.