Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 53, 2023 - Issue 3
96
Views
0
CrossRef citations to date
0
Altmetric
Animal Pharmacokinetics and Metabolism

Combination of losartan and puerarin induced pharmacokinetic interaction in hypertension rats enhances the antihypertensive effect of losartan

&
Pages 201-206 | Received 14 Mar 2023, Accepted 24 Apr 2023, Published online: 02 May 2023

References

  • Ahad A, Raish M, Bin Jardan YA, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. 2020. Potential pharmacodynamic and pharmacokinetic interactions of Nigella sativa and Trigonella foenum-graecum with losartan in L-NAME induced hypertensive rats. Saudi J Biol Sci. 27(10):2544–2550.
  • Bondanelli M, Ambrosio MR, Degli Uberti EC. 2001. Pathogenesis and prevalence of hypertension in acromegaly. Pituitary. 4(4):239–249.
  • Chen D, Zhang HF, Yuan TY, Sun SC, Wang RR, Wang SB, Fang LH, Lyu Y, Du GH. 2022. Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models. Acta Pharmacol Sin. 43(9):2325–2339.
  • Dong B, Yuan S, Hu J, Yan Y. 2018. Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol. 56(1):333–336.
  • Fu R, Li J, Yu H, Zhang Y, Xu Z, Martin C. 2021. The Yin and Yang of traditional Chinese and Western medicine. Med Res Rev. 41(6):3182–3200.
  • Guo YJ, Liang DL, Xu ZS, Ye Q. 2014. In vivo inhibitory effects of puerarin on selected rat cytochrome P450 isoenzymes. Pharmazie. 69(5):367–370.
  • Hakkola J, Hukkanen J, Turpeinen M, Pelkonen O. 2020. Inhibition and induction of CYP enzymes in humans: an update. Arch Toxicol. 94(11):3671–3722.
  • Li J, Li Y, Yuan X, Yao D, Gao Z, Niu Z, Wang Z, Zhang Y. 2023. The effective constituent puerarin, from Pueraria lobata, inhibits the proliferation and inflammation of vascular smooth muscle in atherosclerosis through the miR-29b-3p/IGF1 pathway. Pharm Biol. 61(1):1–11.
  • Li H, Liu L, Xie L, Gan D, Jiang X. 2016. Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol. 54(12):2886–2894.
  • Liu M, Gao Y, Yuan Y, Yang K, Shi S, Zhang J, Tian J. 2020. Efficacy and safety of integrated traditional Chinese and western medicine for corona virus disease 2019 (COVID-19): a systematic review and meta-analysis. Pharmacol Res. 158:104896.
  • Lv J, Shi S, Zhang B, Xu X, Zheng H, Li Y, Cui X, Wu H, Song Q. 2022. Role of puerarin in pathological cardiac remodeling: a review. Pharmacol Res. 178:106152.
  • Lynch T, Price A. 2007. The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects. Am Fam Physician. 76(3):391–396.
  • Nagaraju B, Anilkumar KV. 2021. Pharmacodynamic and pharmacokinetic interaction of losartan with glimepiride-metformin combination in rats and rabbits. Indian J Pharmacol. 53(6):465–470.
  • Niu Z, Qiang T, Lin W, Li Y, Wang K, Wang D, Wang X. 2022. Evaluation of potential herb-drug interactions between shengmai injection and losartan potassium in rat and in vitro. Front Pharmacol. 13:878526.
  • Oliveras A, de la Sierra A. 2014. Resistant hypertension: patient characteristics, risk factors, co-morbidities and outcomes. J Hum Hypertens. 28(4):213–217.
  • Park JW, Kim KA, Il Kim Y, Park JY. 2019. Pharmacokinetic and haemodynamic interactions between amlodipine and losartan in human beings. Basic Clin Pharmacol Toxicol. 125(4):345–352.
  • Peng Y, Wang L, Zhao X, Lai S, He X, Fan Q, He H, He M. 2022. Puerarin attenuates lipopolysaccharide-induced myocardial injury via the 14-3-3γ/PKCε pathway activating adaptive autophagy. Int Immunopharmacol. 108:108905.
  • Sam NH, Nguyen LA, Hadarics M. 2021. Exploring inclusiveness towards immigrants as related to basic values: a network approach. PLoS One. 16(12):e0260624.
  • Shumyantseva VV, Koroleva PI, Bulko TV, Sergeev GV, Usanov SA. 2022. Predicting drug-drug interactions by electrochemically driven cytochrome P450 3A4 reactions. Drug Metab Pers Ther. 37(3):241–248.
  • Smith BE, Madigan VM. 2018. Understanding the haemodynamics of hypertension. Curr Hypertens Rep. 20(4):29.
  • Tan C, Wang A, Liu C, Li Y, Shi Y, Zhou MS. 2017. Puerarin improves vascular insulin resistance and cardiovascular remodeling in salt-sensitive hypertension. Am J Chin Med. 45(6):1169–1184.
  • Wang X, Zhang X, Liu F, Wang M, Qin S. 2017. The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism. Pharm Biol. 55(1):1863–1867.
  • Yang J, Li Y, Li Y, Rui X, Du M, Wang Z. 2020. Effects of atorvastatin on pharmacokinetics of amlodipine in rats and its potential mechanism. Xenobiotica. 50(6):685–688.
  • Zhang L. 2019. Pharmacokinetics and drug delivery systems for puerarin, a bioactive flavone from traditional Chinese medicine. Drug Deliv. 26(1):860–869.
  • Zhang L, Liu L, Wang M. 2021. Effects of puerarin on chronic inflammation: focus on the heart, brain, and arteries. Aging Med. 4(4):317–324.
  • Zhang Y, Lou Y, Wang J, Yu C, Shen W. 2020. Research status and molecular mechanism of the traditional chinese medicine and antitumor therapy combined strategy based on tumor microenvironment. Front Immunol. 11:609705.
  • Zhong LL, Zheng Y, Lau AY, Wong N, Yao L, Wu X, Shao T, Lu Z, Li H, Yuen CS, et al. 2022. Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis. Stroke Vasc Neurol. 7(1):77–85.
  • Zhou T, Wang Z, Guo M, Zhang K, Geng L, Mao A, Yang Y, Yu F. 2020. Puerarin induces mouse mesenteric vasodilation and ameliorates hypertension involving endothelial TRPV4 channels. Food Funct. 11(11):10137–10148.
  • Zhou YX, Zhang H, Peng C. 2014. Puerarin: a review of pharmacological effects. Phytother Res. 28(7):961–975.
  • Zhou YX, Zhang H, Peng C. 2021. Effects of puerarin on the prevention and treatment of cardiovascular diseases. Front Pharmacol. 12:771793.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.