Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 53, 2023 - Issue 4
390
Views
0
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

Comparisons between human and rodent hepatic glutathione S-Transferase activities reveal sex and species differences

ORCID Icon, , ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 223-230 | Received 26 Jan 2023, Accepted 03 May 2023, Published online: 16 Jul 2023

References

  • Alin P, Jensson H, Guthenberg C, Danielson UH, Tahir MK, Mannervik B. 1985. Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing. Anal Biochem. 146(2):313–320.
  • Booth J, Boyland E, Sims P. 1961. An enzyme from rat liver catalysing conjugations with glutathione. Biochem J. 79(3):516–524.
  • Beery AK, Zucker I. 2011. Sex bias in neuroscience and biomedical research. Neurosci Biobehav Rev. 35(3):565–572.
  • Buratti FM, Darney K, Vichi S, Turco L, Di Consiglio E, Lautz LS, Béchaux C, Dorne J-L, Testai E. 2021. Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: meta-analysis and implication for chemical risk assessment. Toxicol Lett. 337:78–90.
  • Combes B, Stakelum GS. 1961. A liver enzyme that conjugates sulfobromophthalein sodium with glutathione. J Clin Invest. 40(6):981–988.
  • Egaas E, Falls JG, Dauterman WC. 1995. A study of gender, strain and age differences in mouse liver glutathione-S-transferase. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 110(1):35–40.
  • Feldman S, Ammar W, Lo K, Trepman E, van Zuylen M, Etzioni O. 2019. Quantifying sex bias in clinical studies at scale with automated data extraction. JAMA Netw Open. 2(7):e196700–e196700.
  • Filomeni G, Rotilio G, Ciriolo MR. 2002. Cell signalling and the glutathione redox system. Biochem Pharmacol. 64(5-6):1057–1064.
  • Garte S, Gaspari L, Alexandrie A-K, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, et al. 2001. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomark Amp Prev. 10(12):1239.
  • Gill H, Tingle M, Park B. 1995. N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity. Br J Clin Pharmacol. 40(6):531–538
  • González P, Tuñón MJ, Manrique V, Garcia-Pardo LA, González J. 1989. Changes in hepatic cytosolic glutathione S-transferases enzymes induced by clotrimazole treatment in rats. Clin Exp Pharmacol Physiol. 16(11):867–871.
  • Habig WH, Pabst MJ, Jakoby WB. 1974. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem. 249(22):7130–7139.
  • Hayes JD, Flanagan JU, Jowsey IR. 2005. Glutathione transferases. Annu Rev Pharmacol Toxicol. 45(1):51–88.
  • Hayes JD, Pulford DJ. 1995. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol. 30(6):445–600.
  • Hayes JD, Strange RC. 2000. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology. 61(3):154–166.
  • Igarashi T, Satoh T, Iwashita K, Ono S, Ueno K, Kitagawa H. 1985. Sex difference in subunit composition of hepatic glutathione S-transferase in rats. J Biochem. 98(1):117–123.
  • Igarashi T, Satoh T, Ueno K, Kitagawa H. 1983. Sex-related difference in the hepatic glutathione level and related enzyme activities in rat. J Biochem. 93(1):33–36.
  • Knight TR, Choudhuri S, Klaassen CD. 2007. Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice. Toxicol Sci. 100(2):513–524.
  • Kurose K, Sugiyama E, Saito Y. 2012. Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials for novel drug development. Drug Metab Pharmacokinet. 27(1):9–54.
  • Lorenz J, Glatt HR, Fleischmann R, Ferlinz R, Oesch F. 1984. Drug metabolism in man and its relationship to that in three rodent species: monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver. Biochem Med. 32(1):43–56.
  • Mannervik B, Board PG, Hayes JD, Listowsky I, Pearson WR. 2005. Nomenclature for Mammalian Soluble Glutathione Transferases. Sies H, Packer L, editors. Methods Enzymol. 401:1–8.
  • Mathew N, Kalyanasundaram M, Balaraman K. 2006. Glutathione S-transferase (GST) inhibitors. Expert Opin Ther Pat. 16(4):431–444.
  • McLellan LI, Hayes JD. 1987. Sex-specific constitutive expression of the pre-neoplastic marker glutathione S-transferase, YfYf, in mouse liver. Biochem J. 245(2):399–406.
  • Mohana K, Achary A. 2017. Human cytosolic glutathione-S-transferases: quantitative analysis of expression, comparative analysis of structures and inhibition strategies of isozymes involved in drug resistance. Drug Metab Rev. 49(3):318–337.
  • Morel F, Aninat C. 2011. The glutathione transferase kappa family. Drug Metab Rev. 43(2):281–291.
  • Murias M, Rachtan M, Jodynis-Liebert J. 2005. Effect of multiple freeze–thaw cycles of cytoplasm samples on the activity of antioxidant enzymes. J Pharmacol Toxicol Methods. 52(2):302–305.
  • Oakley A. 2011. Glutathione transferases: a structural perspective. Drug Metab Rev. 43(2):138–151.
  • Pacifici GM, Boobis AR, Brodie MJ, McManus ME, Davies DS. 1981. Tissue and species differences in enzymes of epoxide metabolism. Xenobiotica. 11(2):73–79.
  • Pemble S, Schroeder KR, Spencer SR, Meyer DJ, Hallier E, Bolt HM, Ketterer B, Taylor JB. 1994. Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J. 300(1):271–276.
  • Seidegård J, Vorachek WR, Pero RW, Pearson WR. 1988. Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci USA. 85(19):7293–7297.
  • Singhal SS, Saxena M, Ahmad H, Awasthi YC. 1992. Glutathione S-transferases of mouse liver: sex-related differences in the expression of various isozymes. Biochim Biophys Acta. 1116(2):137–146.
  • Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem. 150(1):76–85.
  • Soberman RJ, Christmas P. 2003. The organization and consequences of eicosanoid signaling. J Clin Invest. 111(8):1107–1113.
  • Srivastava PK, Waxman DJ. 1993. Sex-dependent expression and growth hormone regulation of class alpha and class mu glutathione S-transferase mRNAs in adult rat liver. Biochem J. 294 (1):159–165.
  • Tahir MK, Guthenberg C, Mannervik B. 1985. Inhibitors for distinction of three types of human glutathione transferase. FEBS Lett. 181(2):249–252.
  • Waxman DJ, Holloway MG. 2009. Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes. Mol Pharmacol. 76(2):215–228.
  • Warholm M, Jensson H, Tahir MK, Mannervik B. 1986. Purification and characterization of three distinct glutathione transferases from mouse liver. Biochemistry. 25(14):4119–4125.
  • White J, Tannenbaum C, Klinge I, Schiebinger L, Clayton J. 2021. The integration of sex and gender considerations into biomedical research: lessons from international funding agencies. J Clin Endocrinol Metab. 106(10):3034–3048.
  • Yang L, Li Y, Hong H, Chang C-W, Guo L-W, Lyn-Cook B, Shi L, Ning B. 2012. Sex differences in the expression of drug-metabolizing and transporter genes in human liver. J Drug Metab Toxicol. 3(3):1000119.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.