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Xenobiotica
the fate of foreign compounds in biological systems
Volume 53, 2023 - Issue 10-11
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Animal Pharmacokinetics and Metabolism

Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation

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Pages 613-620 | Received 15 Sep 2023, Accepted 11 Nov 2023, Published online: 23 Nov 2023

References

  • Basile DP, Anderson MD, Sutton TA. 2012. Pathophysiology of acute kidney injury. Compr Physiol. 2(2):1303–1353. doi: 10.1002/cphy.c110041.
  • Blanco VE, Hernandorena CV, Scibona P, Belloso W, Musso CG. 2019. Acute kidney injury pharmacokinetic changes and its impact on drug prescription. Healthcare (Basel). 7(1):10. doi:10.3390/healthcare7010010.
  • Eltzschig HK, Eckle T. 2011. Ischemia and reperfusion–from mechanism to translation. Nat Med. 17(11):1391–1401. doi:10.1038/nm.2507.
  • Fujii T, Uchino S, Takinami M, Bellomo R. 2014. Validation of the kidney disease improving global outcomes criteria for AKI and comparison of three criteria in hospitalized patients. Clin J Am Soc Nephrol. 9(5):848–854. doi:10.2215/CJN.09530913.
  • Ikeda M, Furukawa H, Imamura H, Shimizu J, Ishida H, Masutani S, Tatsuta M, Kawasaki T, Satomi T. 2002. Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor agent in animal model and in patients with impaired renal function. Cancer Chemother Pharmacol. 50(1):25–32. doi:10.1007/s00280-002-0457-z.
  • Ito Y, Kobuchi S, Shimizu R, Katsuyama Y. 2018. Pharmacokinetic and toxicodynamic evaluation of oxaliplatin-induced neuropathy and hematological toxicity in rats. Cancer Chemother Pharmacol. 81(1):155–161. doi:10.1007/s00280-017-3485-4.
  • Ito Y, Kobuchi S, Takeda M, Morimoto M. 2020. Effect of intact oxaliplatin in plasma on a cold allodynia after multiple administrations in colorectal cancer model rats. Ann Palliat Med. 9(5):3000–3006. doi:10.21037/apm-20-542.
  • Ito Y, Kobuchi S, Takesada W, Takahashi C. 2019. Assessment of oxaliplatin-induced chronic neuropathy and anticancer efficacy through pharmacokinetic and toxicodynamic evaluation of a rat model of colorectal cancer. Anticancer Res. 39(8):4207–4213. doi:10.21873/anticanres.13581.
  • Kim TH, Shin S, Shin JC, Bulitta JB, Weon KY, Yoo SD, Park GY, Jeong SW, Kwon DR, Min BS, et al. 2017. Effect of sipjeondaebo-tang on the pharmacokinetics of S-1, an anticancer agent, in rats evaluated by population pharmacokinetic modeling. Molecules. 22(9):1488. doi:10.3390/molecules22091488.
  • Kobuchi S, Ito Y, Okada K, Imoto K, Kuwano S, Takada K. 2013. Pharmacokinetic/pharmacodynamic modeling of 5-fluorouracil by using a biomarker to predict tumor growth in a rat model of colorectal cancer. J Pharm Sci. 102(6):2056–2067. doi:10.1002/jps.23547.
  • Kobuchi S, Shimizu R, Ito Y. 2020. Semi-mechanism-based pharmacokinetic-toxicodynamic model of oxaliplatin-induced acute and chronic neuropathy. Pharmaceutics. 12(2):125. doi:10.3390/pharmaceutics12020125.
  • Kobuchi S, Tsuda M, Okamura M, Nakamura T, Ito Y. 2023. A pharmacokinetic-pharmacodynamic model predicts uracil-tegafur effect on tumor shrinkage and myelosuppression in a colorectal cancer rat model. Anticancer Res. 43(3):1121–1130. doi:10.21873/anticanres.16257.
  • Liu K, Zhong D, Zou H, Chen X. 2010. Determination of tegafur, 5-fluorouracil, gimeracil and oxonic acid in human plasma using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 52(4):550–556. doi:10.1016/j.jpba.2010.01.026.
  • Matzke GR, Aronoff GR, Atkinson AJ, Jr Bennett WM, Decker BS, Eckardt KU, Golper T, Grabe DW, Kasiske B, Keller F, et al. 2011. Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from kidney disease: improving Global Outcomes (KDIGO). Kidney Int. 80(11):1122–1137. doi:10.1038/ki.2011.322.
  • Michaud J, Dubé P, Naud J, Leblond FA, Desbiens K, Bonnardeaux A, Pichette V. 2005. Effects of serum from patients with chronic renal failure on rat hepatic cytochrome P450. Br J Pharmacol. 144(8):1067–1077. doi:10.1038/sj.bjp.070613.
  • Nikanjam M, Stewart CF, Takimoto CH, Synold TW, Beaty O, Fouladi M, Capparelli EV. 2015. Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing. Cancer Chemother Pharmacol. 75(3):495–503. doi:10.1007/s00280-014-2667-6.
  • Onose J, Imai T, Hasumura M, Ueda M, Hirose M. 2003. Rapid induction of colorectal tumors in rats initiated with 1,2-dimethylhydrazine followed by dextran sodium sulfate treatment. Cancer Lett. 198(2):145–152. doi:10.1016/s0304-3835(03)00316-1.
  • Roberts DM, Sevastos J, Carland JE, Stocker SL, Lea-Henry TN. 2018. Clinical pharmacokinetics in kidney disease: application to rational design of dosing regimens. Clin J Am Soc Nephrol. 13(8):1254–1263. doi:10.2215/CJN.05150418.
  • Rosner MH, Perazella MA. 2017. Acute kidney injury in patients with cancer. N Engl J Med. 376(18):1770–1781. doi:10.1056/NEJMra1613984.
  • Takayama J, Takaoka M, Matsumura tY. 2008. Acute and chronic renal failure model in rats and mice. Nihon Yakurigaku Zasshi. 131(1):37–42. doi:10.1254/fpj.131.37.
  • Takeda F, Oda M, Terasaki M, Kubota A, Asada K, Ichimura Y, Kojima H, Saitoh H. 2021. Downregulated expression of organic anion transporting polypeptide (Oatp) 2b1 in the small intestine of rats with acute kidney injury. Drug Metab Pharmacokinet. 40:100411. doi:10.1016/j.dmpk.2021.100411.
  • Takimoto CH, Graham MA, Lockwood G, Ng CM, Goetz A, Greenslade D, Remick SC, Sharma S, Mani S, Ramanathan RK, et al. 2007. Oxaliplatin pharmacokinetics and pharmacodynamics in adult cancer patients with impaired renal function. Clin Cancer Res. 13(16):4832–4839. doi:10.1158/1078-0432.CCR-07-0475.
  • Thangaraj K, Natesan K, Settu K, Palani M, Govindarasu M, Subborayan V, Vaiyapuri M. 2018. Orientin mitigates 1, 2-dimethylhydrazine induced lipid peroxidation, antioxidant and biotransforming bacterial enzyme alterations in experimental rats. J Cancer Res Ther. 14(6):1379–1388. doi:10.4103/jcrt.JCRT_1363_16.
  • Tokunaga A, Miyamoto H, Fumoto S, Nishida K. 2019. Effect of renal ischaemia/reperfusion-induced acute kidney injury on pharmacokinetics of midazolam in rats. J Pharm Pharmacol. 71(12):1792–1799. doi:10.1111/jphp.13167.
  • Wang BY, Li QX, Li J, Xie XF, Ao Y, Ai YX. 2009. Hepatotoxicity and gene expression down-regulation of CYP isozymes caused by renal ischemia/reperfusion in the rat. Exp Toxicol Pathol. 61(2):169–176. doi:10.1016/j.etp.2008.12.010.
  • Watanabe D, Fujii H, Yamada Y, Iihara H, Ishihara T, Matsuhashi N, Takahashi T, Yoshida K, Suzuki A. 2020. Relationship between renal function and the incidence of adverse events in patients with colorectal cancer receiving oxaliplatin. Anticancer Res. 40(1):299–304. doi:10.21873/anticanres.13953.
  • Yamada Y, Takahari D, Matsumoto H, Baba H, Nakamura M, Yoshida K, Yoshida M, Iwamoto S, Shimada K, Komatsu Y, et al. 2013. Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): an open-label, non-inferiority, randomised phase 3 trial. Lancet Oncol. 14(13):1278–1286. doi:10.1016/S1470-2045(13)70490-X.
  • Yonezawa A, Inui K. 2011. Organic cation transporter OCT/SLC22A and H(+)/organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents. Biochem Pharmacol. 81(5):563–568. doi:10.1016/j.bcp.2010.11.016.
  • Zhuang ZX, Zhu H, Wang J, Zhu MG, Wang H, Pu WY, Bian HH, Chen L, Zhang H. 2013. Pharmacokinetic evaluation of novel oral fluorouracil antitumor drug S-1 in Chinese cancer patients. Acta Pharmacol Sin. 34(4):570–580. doi:10.1038/aps.2012.169.
  • Zuk A, Bonventre JV. 2016. Acute kidney injury. Annu Rev Med. 67(1):293–307. doi:10.1146/annurev-med-050214-013407.

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