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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 10
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Research Article

Intermediary metabolism of pentachloronitrobenzene in the control and germfree rat and rat with cannulated bile ducts

G. L. LARSEN US Department of Agriculture, Agricultural Research Service, Biosciences Research Laboratory, PO Box 5674-University Station, Fargo, ND 58105-5674, USA
Pages 973-984 | Published online: 22 Sep 2008

References

  • ASCHBACHER, P. W. and FEIL, V. J., 1983, Metabolism of pentachloronitrobenzene by goats and sheep. Journal of Agricultural and Food Chemistry, 31, 1150–1158.
  • BAKKE, J. E., ASCHBACHER, P. W., FoL, V. J. and GUSTAFSSON, B. E., 1981, The metabolism of pentachloromethylthiobenzene in germ-free and conventional rats. Xenobiotica, 11, 173–178.
  • BAKKE, J. E., FEIL, V. J. and PRICE, C. E., 1976, Rat urinary metabolites from 0,0-diethyl-0-(3,5,6-trichloro-2-pyridyl)phosphorothioate. Journal of Environmental Science and Health, B11, 225–230.
  • BAKKE, J. E., FoL, V. J. and ZAYLSKIE, R. G., 1989, Isotope dilution assay for urinary methanesulfinic and methanesulfonic acids: application to detection of methylthio turnover. Biomedical and Environmental Mass Spectrometry, 18, 1096–1098.
  • BAKKE, J. E., GUSTAFSSON, J.-A. and GUSTAFSSON, B. E., 1980, Metabolism of propachlor by the germ-free rat. Science 210, 433–435.
  • BAKKE, J. E., MULFORD, D. J., HUWE, J. K., Fat, V. J. and DAVISON, K. L., 1993, Glutathione-mediated methylthio -turnover and sex differences in the metabolism of pentachlorothioanisole by rats. Xenobiotica, 23, 949–960.
  • BOLLMAN, J. L., 1948, A cage which limits the activity of rats. Journal of Laboratory and Clinical Medicine, 33, 1348.
  • DUGGAN, D. E. and KWAN, K. C., 1979, Enterohepatic recirculation of drugs as a determinant of therapeutic ratio, Drug Metabolism Reviews, 9, 21–41.
  • GOLDMAN, P., 1989, Germ-free rats in the study of the metabolism of xenobiotic compounds. In Intermediary Xenobiotic Metabolism in Animals, edited by D. H. Hutson, V. Caldwell and G. D. Paulson (London: Taylor & Francis), pp. 263–276.
  • HUWE, J. K., FEIL, V. J., BAKKE, J. E. and MULFORD, D. J., 1991, Studies on the displacement of methylthio groups by glutathione. Xenobiotica, 21, 179–191.
  • K6GEL, W., MULLER, W. F., COULSTON, F. and KORTE, F., 1979, Biotransformation of pentachloro-nitrobenzene- C in Rhesus monkeys after single and chronic oral administration. Chemosp here, 8, 97–105.
  • LARSEN, G. L., 1985, Distribution of cysteine conjugate f3-lyase in gastrointestinal bacteria and in the environment. Xenobiotica, 15, 199–209.
  • LARSEN, G. L. and BAKKE, J. E., 1981, Enterohepatic circulation in formation of propachlor (2-chloro-N-isopropylacetanilide) metabolites in the rat. Xenobiotica, 11, 473–480.
  • MULFORD, D. J., BAKKE, J. E. and FEIL, V. J., 1991, Glutathione-S-transferase-mediated methylthio-displacement and -turnover in the metabolism of pentachlorothioanisole by rats. Xenobiotica, 21, 597–603.
  • GRODNICK, J. S., ADAMOVICS, J. A., BLAKE, S. H. and WIG, J., 1981, The metabolic fate of C-labelled pentachloronitrobenzene in Osborne—Mendell rats. Chemosphere, 10, 67–72.
  • PAULSON, G. D., MITCHELL, A. D. and ZAYLSKIE, R. G., 1985, Identification and quantitation of sulfamethazine metabolites by liquid chromatography and gas chromatography—mass spec-trometry. Journal of the Association of Official Analytical Chemists, 68, 1000–1006.
  • QUIRUINS, J. K., VAN DER PAAUW, C. G., TEN NOEVER DE BRAUW, M. C. and DE VOS, R. H., 1979, Survey of the contamination of Dutch coastal waters by chlorinated hydrocarbons, including the occurrence of methylthiopentachlorobenzene and di-(methylthio)tetrachlorobenzene. Science of the Total Environment, 13, 225–233.
  • RENNER, G., 1980, Metabolic studies on pentachloronitrobenzene (PCNB) in rats. Xenobiotica, 10, 537–550.
  • SAMARA, E., BIALER, M. and HARVEY, D. J., 1990, Identification of glucose conjugates as major urinary metabolites of cannabidiol in the dog. Xenobiotica, 20, 177–183.
  • SOINE W. H., SOINE, P. J., MONGRAIN, S. E. and ENGLAND, T. M., 1990, Stereochemical charac-terization of the diastereomers of the phenobarbital N-beta-D-glucose conjugate excreted in human urine. Pharmacological Research, 7, 402–406.
  • TROkLER, P. C. and REYNOLDS, L. I., 1957, Flexible film apparatus for the rearing and use of germ-free animals. Applied Microbiology, 5, 406–412.
  • WEISIGER, R. A., PINKUS, L. M. and JAKOBY, W. B., 1980, Thiol S-methyltransferase: suggested role in detoxification of intestinal hydrogen sulfide. Biochemical Pharmacology, 29, 2885–2887.

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