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Xenobiotica
the fate of foreign compounds in biological systems
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Research Article

Pharmacokinetic properties and oral bioavailabilities of difloxacin in pig and chicken

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Pages 887-893 | Published online: 22 Sep 2008

References

  • ANAD6N, A., MARTINEZ -LARRAIZIAGA, M. R., VELEZ, C., DIAZ, M. J. and BRINGAS, P., 1992, Pharmaco-kinetics of norfloxacin and its N-desethyl- and oxo-metabolites in broiler chickens. American Journal of Veterinary Research, 53, 2084–2089.
  • ANADCiN, A., MARTINEZ -LARRAKAGA, M. R., DIAZ, M. J., BRINGAS, P., MARTINEZ, M. A., FERNXNDEZ - CRUZ, M. L., FERNXNDEZ, M. C. and FERNXNDEZ, R., 1995, Pharmacokinetics and residues of enrofloxacin in chickens. American Journal of Veterinary Research, 56, 501–506.
  • BROOME, R. L., BROOKS, D. L., BABISH, J. G., COPELAND, D. D. and CONZELMAN, G. M., 1991, Pharrnacokinetic properties of enrofloxacin in rabbits. American Journal of Veterinary Research, 52, 1835–1841.
  • CABANES, A., ARBO1X, M., GARCIA ANTON, J. M. and ROG, F., 1992, Pharmacokinetics of enrofloxacin after intravenous and intramuscular injection in rabbits. American Journal of Veterinary Research, 53, 2090–2093.
  • CHu, D. T. W., GRANNEMAN, G. R. and FERNANDES, P. B., 1985, ABBOTT-56619. Drugs of the Future, 10, 543–545.
  • ELIOPOULOS, G. M., MOELLERING, A. E., REISZNER, E. and MOELLERING, R. C. JR, 1985, In vitro activities of the quinolone antimicrobial agents A-56619 and A-56620. Antimicrobial Agents and Chemotherapy, 28, 514–520.
  • FERNANDES, P. B., CHU, D. T. W., BOWER, R. R., JARVIS, K. P., RAMER, N. R. and SHIPKOWITZ, N., 1986, In vivo evaluation of A-56619 (Difloxacin) and A-56620: new aryl-fluoroquinolones. Antimicrobial Agents and Chemotherapy, 29, 201–208.
  • GILES, C. J., MAGONIGLE, R. A., GRIMSHAW W. T. R., TANNER, A. C., RISK, J. E., LYNCH, M. J. and RICE, J. R., 1991, Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. Journal of Veterinary Pharmacology and Therapeutics, 14, 400–410.
  • GRANNEMAN, G. R. and SENNELLO, L. T., 1987, High-performance liquid chromatographic procedures for the determination of difloxacin and its metabolites in biological matrices. Journal of Chromatography, 413, 199–206.
  • GRANNEMAN, G. R., SNYDER, K. M. and SHu, V. S., 1986, Difloxacin metabolism and pharmacokinetics in human after single oral doses. Antimicrobial Agents and Chemotherapy, 30, 689–693.
  • JEHL, F., BRESLER, L., KOECHLIN C., MERLE -MELET M DIDELOT, J. P. and HAZEBROUCQ, J., 1992, Pharmacokinetics and biliary elimination of temafloxacin in pigs. Journal of Antimicrobial Chemotherapy, 30, 189–196.
  • KENNY, G. E., HOOTON, T. M., ROBERTS, M. C., CARTWRIGHT, F. D. and HOYT, J., 1989, Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method. Antimicrobial Agents and Chemotherapy, 33, 103–107.
  • MING, K., RIOND, J. L. and WANNER, M., 1993, Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs. Journal of Veterinary Pharmacology and Therapeutics, 16, 462–468.
  • LYNCH, M. J., RICE, J. R., ERICSON, J. F., MOSHER, F. R., MILLAS W. J., HARRAN, L. P., FRAME, G. M., ILLYES, E. F., McGuIRK, P. R., JEFSON, M. R., RISK, J. E. and MAGONIGLE, R. A., 1994, Residue depletion studies of danofloxacin in the chicken. Journal of Agricultural and Food Chemistry, 42, 289–294.
  • MANN, D. D. and FRAME, G. M., 1992, Pharmacokinetic study of danofloxacin in cattle and swine. American Journal of Veterinary Research, 53, 1022–1026.
  • MENGOZZI, G., INTORRE L, BERTINI, S. and SOLDANI, G., 1996, Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular administrations in sheep. American Journal of Veterinary Research, 57, 1040–1043.
  • NIELSEN, P. and GYRD-HANSEN, N., 1997, Bioavailability of enrofloxacin after oral administration to fed and fasted pigs. Pharmacology and Toxicology, 80, 246–250.
  • OGATA, H., 1985, Calculation of bioavailability. In Applied Pharmacokinetics: Theory and Experiments, edited by M. Hanano, K. Umemura and T. Iga (Tokyo: Soft Science), pp. 547–548.
  • STAMM, J. M., HANSON, C. W., CHU, D. T. W., BAILER, R., VOJTKO, C. and FERNANDES, P. B., 1986, In vitro evaluation of A-56619 (Difloxacin) and A-56620: new aryl-fluoroquinolones. Antimicrobial Agents and Chemotherapy, 29, 193–200.
  • WALKER, R. D., STEIN, G. E., HAUPTMAN, J. G. and MAcDONALD, K. H., 1992, Pharmacokinetic evaluation of enrofloxacin administered orally to healthy dogs. American Journal of Veterinary Research, 53, 2315–2319.

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