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Xenobiotica
the fate of foreign compounds in biological systems
Volume 28, 1998 - Issue 3
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Research Article

Partial hepatoprotective effects of allylthiobenzimidazole in the absence of cytochrome P4502E1 suppression: effects on epoxide hydrolase, rGSTA2, rGSTA3/5, rGSTM1 and rGSTM2 expression

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Pages 323-336 | Published online: 22 Sep 2008

References

  • BUETLER, T. M., GALLAGHER, E. P., WANG, C., STAHL, D. L., HAYES, J. D. and EATON, D. L., 1995, Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin and oltipraz. Toxicology and Applied Pharmacology, 135, 45–57.
  • DANIEL, V., 1993, Glutathione S-transferases : gene structure and regulation of expression. Critical Reviews in Biochemistry and Molecular Biology, 28, 173–207.
  • DAUJAT, M., CHARRASSE, S., FABRE, I., LESCA, P., JOUNAIDI, Y., LARROQUE, C., POELLINGER, L. and MAUREL, P., 1996, Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. European Journal of Biochemistry, 237, 642–652.
  • GRIFFITH, O. W., 1980, Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Analytical Biochemistry, 106, 207–212.
  • HAS, J. D. and PULFORD, D. J., 1995, The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to chemoprotection and drug resistance. Critical Reviews in Biochemistry and Molecular Biology, 30, 445–600.
  • JAISWAL, A. K., 1994, Antioxidant response element. Biochemical Pharmacology, 48, 439–444.
  • KARENLAMPIS. O., Tuomi, K., KORKALAINEN, M. and RAUNIO, H., 1989, 2-(4'-chloro-phenyl)benzothiazole is a potent inducer of cytochrome P450IA1 in a human and a mouse cell line. Anomalous correlation between protein and mRNA induction. European Journal of Biochemistry, 181, 143–148.
  • KENSLER, T. W., EGNER, P. A., DOLAN, P.M., GROOPMAN, J. D. and ROEBUCK, B. D., 1987, Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyraziny1)-4-methy1-1,2-dithio1-3-thione (oltipraz) and related 1,2-dithio1-3-thiones and 1,2-dithio1-3-ones. Cancer Research, 47, 4271–4277.
  • KIKUCHI, H., KATO, H., MIZUNO, M., HOSSAIN, A., IKAWA, S., MIYAZAKI, J. and WATANABE, M., 1996, Differences in inducibility of CYP1A1-mRNA by benzimidazole compounds between human and mouse cells: evidences of a human-specific signal transduction pathway for CYP1A1 induction. Archives of Biochemistry and Biophysics, 334, 235–240.
  • KIM, N. D., KWAK, M. K. and KIM, S. G., 1997a, Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects. Biochemical Pharmacology, 53, 261–269.
  • KIM, S. G., 1992, Transcriptional regulation of rat microsomal epoxide hydrolase gene by imidazole antimycotic agents. Molecular Pharmacology, 42, 273–279.
  • KIM, S. G. and CH0, M. K., 1996, Expression of glutathione S-transferase Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase gene by thiazole, benzothiazole and benzothiadiazole. Biochemical Pharmacology, 52, 1831–1841.
  • KIM, S. G., CHUNG, H. C. and CH0, J. Y., 1996, Molecular mechanism for alkyl sulfide-modulated carbon tetrachloride-induced hepatotoxicity : the role of P4502E1, P4502B and glutathione S-transferase expression. Journal of Pharmacology and Experimental Therapeutics, 277, 1058–1066.
  • KIM, S. G., KEDDERIS, G. L., BATRA, R. and NOVAK, R. F., 1993, Thiazole and pyrazine induction of microsomal epoxide hydrolase in rats: 2-cyanoethylene oxide hydrolysis. Carcinogenesis, 14, 1665–1670.
  • KIM, S. G. and KIM, Y. H., 1992, Gender-related expression of rat microsomal epoxide hydrolase during maturation: post-transcriptional regulation. Molecular Pharmacology, 42, 75–81.
  • KIM, S. G., NAM, S. Y., CHoi, S. H., Kim, C. W., CH0, C. K., KWAK, M. K. and KIM, N. D., 1998, Radioprotective effects of 2 -(allylthio)pyrazine an experimental hepatoprotective agent: effects on hepatic microsomal epoxide hydrolase and glutathione S-transferase induction (submitted).
  • KIM, S. G., NAM, S. Y., Kim, J. H., CHO, C. K. and Yoo, S. Y., 1997b, Enhancement of radiation-inducible hepatic glutathione S-transferase Ya, Yb1, Yb2, Yc1, and Yc2 expression by oltipraz: possible role in radioprotection. Molecular Pharmacology, 51, 225–233.
  • KIM, S. G. and NOVAK, R. F., 1993, The induction of cytochrome P4502E1 by nitrogen- and sulfur-containing heterocycles: expression and molecular regulation. Toxicology and Applied Phar-macology, 120, 257–265.
  • KOSTRUO. H., ROSEBROUGH, N. J., FARR, A. L. and RANDALL, F. J., 1951, Protein measurement with the folin phenol reagent. Journal of Biological Chemistry, 193, 265–275.
  • NORFORD, D. C., MENTEN, D. J., CULLEN, J. M. and COLLINS, J. J., 1993, Pituitary and thyroid gland lesions induced by 2-mercaptobenzimidazole inhalation in male Fischer 344 rats. Toxicologic Pathology, 21, 456–464.
  • PUISSANT, C. and HOUDEBINE, L.-M., 1990, An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques, 8, 148–149.
  • REY -GROBELLET X., FRERE, N., EECKHOUTTE C., LARR1EU, G., PINEAU, T. and GALTIER, P., 1996, Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultured rabbit hepatocytes. Biochemical and Biophysical Research Communications, 220, 789–794.
  • RUSHMORE, T. H., MORTON, M. R. and PICKETT, C. B., 1991, The antioxidant responsive element. Journal of Biological Chemistry, 266, 11632–11639.
  • TALLARIDA, R. J. and MURRAY, R. B., 1987, Manual of Pharmacologic Calculations with Computer Programs (New York: Springer).
  • TSUCHIYA, T., HISANO, T., TANAKA, A. and TAKAHASHI, A., 1987, Effects of benzimidazoles on mouse and rat limb bud cells in culture. Toxicology Letters, 38, 97–102.
  • YAMANO, T., NODA, T., SHIMIZU, M. and MORITA, S., 1995, The adverse effects of oral 2-mercaptobenzimidazole on pregnant rats and their fetuses. Fundamental and Applied Toxicology, 25, 218–223.

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