Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat

References

• BECKMAN, K. B. and Avis, B. N., 1997, Oxidative decay of DNA. Journal of Biological Chemistry, 272, 19633–19366.
   PubMed Web of Science ®Google Scholar
• BLOCK, G. and LANGSETH, L., 1994, Antioxidant vitamins and disease prevention. Food Technology, July, 80–84.
   Google Scholar
• BOILS, W. and SARAN, M., 1987, Radical scavenging by flavonoid antioxidants. Free Radical Research Communications, 2, 289–294.
   PubMedGoogle Scholar
• BREINHOLT, V., 1999, Desirable versus harmful levels of intake of flavonoids and phenolic acids. In J. T. Kumpulainen and J. T. Salonen (eds), Natural Antioxidants in Nutrition, Health and Disease (Cambridge: Royal Society of Chemistry), pp. 93-10S.
   Google Scholar
• BROUARD, C., SIESS, M.-H., VERNEVAUT, M.-F. and SUSCHETET, M., 1988, Comparison of the effects of feeding quercetin or flavone on hepatic and intestinal drug-metabolizing enzymes of the rat. Food and Chemical Toxicology, 26, 99–103.
   Google Scholar
• BUENING, M. K., CHANG, R. L., HUANG, M.-T., FORTNER, J. G., WOOD, A. W. and Coy, A. H., 1981, Activation and inhibition of benzo[a]pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids. Cancer Research, 41, 67–72.
   Google Scholar
• BURKE, M. D., THOMPSON, S., WEAVER, R. J., WOLF, C. R. and MAYERS, R. T., 1994, Cytochrome P450 specificities of alkylresorufin 0-dealkylation in human and rat liver. Biochemical Pharmacology, 48, 923–936.
   PubMed Web of Science ®Google Scholar
• CANIVENC-LAVIER, M.-C., VERNEVAUT, M.-F., TOTES, M., SIESS, M.-H., MAGDALOU, J. and SUSCHETET M., 1996, Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver. Toxicology, 114, 19–27.
   Google Scholar
• CHAE, Y. H., MARCUS, C. B., Ho, D. K., CASSADY, J. M. and BAIRD, W. M., 1991, Effects of synthetic and naturally occurring flavonoids on benzo(a)pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers. Cancer Letters, 60, 15–24.
   PubMed Web of Science ®Google Scholar
• CHOLBI, COMM, M. R., PAYA, M. and ALCARAZ, M. J., 1991, Inhibitory effects of phenolic compounds on CCL4-induced microsomal lipid peroxidation. Experimentia, 47, 195–199.
   Google Scholar
• CONSTANT, J., 1997, Alcohol, ischemic heart disease, and the French paradox. Coronary Artery Disease, 8, 645–649.
   PubMed Web of Science ®Google Scholar
• CROFTS, F. G, SUTTER, T. R. and STRICKLAND, P. T., 1998, Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1. Carcino-genesis, 19, 1969–1973.
   Google Scholar
• DASHWOOD, R. H., ARBOGAST D. N., FONG, A. T., HENDRICKS, J. D. and BAILEY, G. S., 1988, Mechanisms of anticarcinogenesis by indole-3-carbinol: detailed in vivo DNA-binding dose-response studies after dietary administration with aflatoxin B1. Carcinogenesis, 9, 427432.
   Google Scholar
• DRAGSTED, L. 0., ALEXANDER, J., WALIIN, H., FRANDSEN, H. and YANG. 0., 1993, Bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine by liver microsomes from three different rat strains. Pharmacology and Toxicology, 72, 388–393.
   Google Scholar
• DREHER, D. and JuNoD, A. F., 1996, Role of oxygen free radicals in cancer development. European Journal of Cancer, 32A, 30–38.
   PubMed Web of Science ®Google Scholar
• ERNSTER, L., 1967, DT diaphorase. Methods in Enzymology, 10, 309–317.
   Google Scholar
• FRAGA, C. G., MARTINO, V. S., FERRARO, G. E., Coussio, J. D. and BOVERIS, A., 1987, Flavonoids as antioxidants evaluated by in vitro and in situ liver chemiluminescence. Biochemical Pharmacology, 36, 717–720.
   PubMed Web of Science ®Google Scholar
• FUHR, U., Kurrico, K. and STAIB, H., 1993, Inhibitory effects of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man. British Journal of Clinical Pharmacology, 35, 431–436.
   PubMed Web of Science ®Google Scholar
• GOLDBERG, D. M. and SPOONER, R. J., 1983, In Methods of Enzymatic Analysis, 3rd edn (Deerfield Beach: Chemie), vol. 3, pp. 258–265.
   Google Scholar
• HABIG, W. H., PABST, M. J. and JAcoBY, W. B., 1974, Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry, 249, 7130–7139.
   PubMed Web of Science ®Google Scholar
• HALuwELL, B., 1996, Oxidative stress, nutrition and health. Experimental strategies for optimization of nutritional antioxidant intake in humans. Free Radical Research, 25, 57–74.
   PubMedGoogle Scholar
• HALuwELL, B. and GUITERIDGE, M. C., 1990, Role of free radicals and catalytic metal ions in human disease: An overview. Methods in Enzymology, 186, 1–83.
   Google Scholar
• HUANG, M.-T., JOHNSON, E. F., MULLER -EBERHARD U., KOOP, D. R., COON, M. J. and CONNEY, A. H., 1981, Specificity in the activation and inhibition by flavonoids of benzo[a]flavone hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. Journal of Biological Chemistry, 21, 10897–10901.
   Google Scholar
• ITo, N., HASEGAWA, R., SANO, M., TAIVIANO S., ESUMI, H., TAKAYAIVIA, S. and SUGUVIURA, T., 1991, A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP). Carcinogenesis, 12, 1503–1506.
   Google Scholar
• KADERLIK, R. K., MiNcortv, R. F., MULDER, G. J., ILETT, K. F., DAUGAARD- JENSON, M., TEITEL, C. H. and KALUBAR, F. F., 1994, Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues. Carcinogenesis, 15, 1703–1709.
   Google Scholar
• LAKE, B. G., 1987, Preparation and characterization of microsomal fractions for studies on xenobiotic metabolism. In K. Snell and B. Mullock (eds), Biochemical Toxicology: A Practical Approach (Oxford: IRL Press), pp. 183–215.
   Google Scholar
• LASKER, J. M., HUANG, M.-T. and CoNNEY, A. H., 1983, In vitro and in vivo activation of oxidative drug metabolism by flavonoids. Journal of Pharmacology and Experimental Therapeutics, 229, 162–170.
   Google Scholar
• LEE, H., WANG, H.-W., Su, H.-Y. and HAO, N. J., 1994, The structure-activity relationship of flavonoids as inhibitors of cytochrome P-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-fiquinoline. Mutagenesis, 9, 101–106.
   Google Scholar
• LI, Y., WANG, E., PAULEN, C. J., CHEN, L. and YANG, C. S., 1994, Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes. Drug Metab-olism and Disposition, 22, 566–571.
   PubMed Web of Science ®Google Scholar
• LONCHAMPT, M., GUARDIOLA, B., SICOT, N., BERTRAND, M., PERDRDC, L. and DUHAULT J., 1989, Protective effect of purified flavonoid fraction against reactive oxygen radicals. Arzneimittel Forschung. 39, 882–885.
   Google Scholar
• MEYER, O., BLOM, L. and SNDERGAARD, D., 1982, The influence of minerals and protein on the nephrocalcinosis potential for rats of semi-synthetic diets. Laboratory Animals, 16, 271–273.
   Google Scholar
• MONBOISSE, J. C., BRAQUET, P., RANDOUX, A. and BOREL, J. P., 1983, Non-enzymatic degradation of acid-soluble calf skin collagen by superoxide ion: protective effect of flavonoids. Biochemical Pharmacology, 32, 53–58.
   PubMed Web of Science ®Google Scholar
• MORA, A., PAYA, M., Rios, J. L. and ALCARAZ, M. J., 1990, Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymatic lipid peroxidation. Biochemical Pharmacology, 40, 793–797.
   PubMed Web of Science ®Google Scholar
• MULDER, G. J. and VAN DOORN, A. B. D., 1975, A rapid NADtlinked assay for microsomal uridine diphosphate glucuronyltransfera of rat liver and some observations on substrate specificity of the enzyme. Biochemical Journal, 151, 31–41.
   Google Scholar
• NIELSEN, S. E., BREINHOLT, V., JUSTESEN, U., CORNETT, C. and DRAGSTED, L. 0., 1998, In vitro biotransformation of flavonoids by rat liver microsomes. Xenobiotica, 28, 389401.
   Google Scholar
• REDINBAUGH, M. G. and RURLEY, R. B., 1986, Adoption of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions. Analytical Biochemistry, 153, 267-271. RICE -EVANS, C. A., MILLER, N. J. and PAGANGA, G., 1996, Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radicals in Biology and Medicine, 20, 933–956.
   Google Scholar
• SIESS, M. H. GUILLARMIC, M., LE BON, A. M. and SUSCHETET, M., 1989, Induction of monooxygenase and transfera activities in rat by dietary administration of flavonoids. Xenobiotica, 19, 1379–1386.
   PubMed Web of Science ®Google Scholar
• SIESS, M. H., BROUARD, VERNEVAUT, M. F. and SUSCHETET, M., 1988, Effects of feeding quercetin and flavone on hepatic drug metabolizing enzymes of rats. Progress in Clinical and Biological Research, 280, 147–150.
   Google Scholar
• SIESS, M.-H., LECLERC, J., CANIVENC -LAVIER, M.-C., RAT, P. and SUSCHETET, M., 1995, Heterogeneous effects of natural flavonoids on monooxygenase activities in human and rat liver microsomes. Toxicology and Pharmacology, 130, 73–78.
   Google Scholar
• SIESS, M.-H., MAS, J.-P., CANIVENC -LAVIER, M.-C. and SUSCHETET, M., 1996, Time course of induction of rat hepatic drug-metabolizing enzyme activities following dietary administration of flavonoids. Journal of Toxicology and Environmental Health, 49, 481–496.
   Google Scholar
• TALALAY, P., 1989, Mechanisms of induction of enzymes that protect against chemical carcinogens. Advances in Enzyme Regulation, 28, 237–250.
   PubMedGoogle Scholar
• TALALAY, P., DE LONG, M. J. and PROCHASKA, H. J., 1987, Molecular mechanisms in protection against carcinogenesis. In J. G. Cory and A. Szentivani (eds), Cancer Biology and Therapeutics (New York: Plenum), pp. 197–216.
   Google Scholar
• TSYRLOV, I. B., MIKHAILENKO, V. M. and BELBOIN, H. V., 1994, Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-45 Os to different flavonoids. Biochimica et Biophysica Acta, 1205, 325–335.
   PubMed Web of Science ®Google Scholar
• WANG, Z. Y., Dm, M., BICKERS, D. R. and MUKITTAR, H., 1988, Interaction of epicatechins derived from green tea with rat hepatic cytochrome P-450. Drug Metabolism and Disposition, 16, 98–103.
   PubMed Web of Science ®Google Scholar
• WATTENBERG, L. W., 1983, Inhibition of neoplasia by minor dietary constituents. Cancer Research, 43 (suppl.), 2448s–2453s.
   Google Scholar
• WATTENBERG, L. W., 1985, Chemoprevention of cancer. Cancer Research, 45, 1–8.
   PubMed Web of Science ®Google Scholar
• WHEELER, C. R., SALZMAN, J. A., ELSAYED, N. M., OMAYE S. T. and KORTE, D. W., 1990, Automated assays for superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activity .Analytkal Biochemistry, 184, 193–199.
   Google Scholar
• ZHANG, Q. Y. WIKOFF, J. DUNBAR, D. and KAmmsKY, L., 1996, Characterization of rat small intestinal cytochrome P450 composition and inducibility. Drug Metabolism and Disposition, 24, 322–328.
   Google Scholar