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Journal of Obstetrics and Gynaecology Volume 39, 2019 - Issue 3
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Original Article

Diagnostic pitfalls in ovarian androgen-secreting (Leydig cell) tumours: case series

M. Fantaa 1st Faculty of Medicine, Department of Gynaecology and Obstetrics, Charles University and General University Hospital, Prague, Czech Republic; Correspondence[email protected]
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,
D. Fischerováa 1st Faculty of Medicine, Department of Gynaecology and Obstetrics, Charles University and General University Hospital, Prague, Czech Republic; View further author information
,
T. Indrielle-Kellya 1st Faculty of Medicine, Department of Gynaecology and Obstetrics, Charles University and General University Hospital, Prague, Czech Republic; ;b Department of Gynaecology and Obstetrics, Queen’s Hospital, Burton Hospitals NHS Trust, Staffordshire, UK; View further author information
,
P. Kolibaa 1st Faculty of Medicine, Department of Gynaecology and Obstetrics, Charles University and General University Hospital, Prague, Czech Republic; View further author information
,
A. Zdeňkováa 1st Faculty of Medicine, Department of Gynaecology and Obstetrics, Charles University and General University Hospital, Prague, Czech Republic; View further author information
,
A. Burgetovác 1st Faculty of Medicine, Department of Radiology, Charles University and General University Hospital, Prague, Czech Republic; View further author information
&
J. Vrbíkovád Institute of Endocrinology, Prague, Czech RepublicView further author information
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Pages 359-364 | Published online: 14 Nov 2018

References

  • Demidov VN, Lipatenkova J, Vikhareva O, Van Holsbeke C, Timmerman D, Valentin L. 2008. Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli–Leydig cell tumors and Leydig cell tumors. Ultrasound in Obstetrics and Gynecology 31:85–91.
  • Escobar-Morreale HF, Carmina E, Dewailly D, Gambineri A, Kelestimur F, Moghetti P, et al. 2012. Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society. Human Reproduction Update 18:146.
  • Friedman CI, Schmidt GE, Kim MH, Powell J. 1985. Serum testosterone concentrations in the evaluation of androgen-producing tumors. American Journal of Obstetrics and Gynecology 153:44.
  • Gheorghisan-Galateanu A, Fica S, Terzea DC, Caragheorgheopol A, Horhoianu V. 2003. Sertoli–Leydig cell tumor – a rare androgen secreting ovarian tumor in postmenopausal women. Case report and review of literature. Journal of Cellular and Molecular Medicine 7:461–471.
  • Inoue Y, Kamura T, Okuma A, Shigematsu T, Amada S, Ogata R, et al. 1999. Efficacy of selective venous sampling to localize a small ovarian androgen-producing tumor. Journal of Obstetrics and Gynaecology Research 25:231–236.
  • Magyar E, Kisfaludy N. 2002. Leydig cell tumors not classified as Sertoli–Leydig group. CME Journal of Gynecologic Oncology 7:164–166.
  • Martin KA, Chang RJ, Ehrmann DA, Ibanez L, Lobo RA, Rosenfield RL, et al. 2008. Evaluation and treatment of hirsutism in premenopausal women: an endocrine society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism 93:1105.
  • Meldrum DR, Abraham GE. 1979. Peripheral and ovarian venous concentrations of various steroid hormones in virilizing ovarian tumors. Obstetrics and Gynecology 53:36.
  • Nardo LG, Ray DW, Laing I, Williams C, McVey RJ, Seif MW. 2005. Ovarian Leydig cell tumor in a peri-menopausal woman with severe hyperandrogenism and virilization. Gynecological Endocrinology 21:238–241.
  • Rosenfield RL. 2005. Clinical practice. Hirsutism. New England Journal of Medicine 353:2578.
  • Timmerman D, Valentin L, Bourne TH, Collins WP, Verrelst H, Vergote I. 2000. Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) Group. Ultrasound in Obstetrics & Gynecology 16:500.

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