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Journal of Obstetrics and Gynaecology Volume 40, 2020 - Issue 4
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Case Reports

Inadvertent foetal exposure to methylene blue in the first trimester

Callum J. DonaldsonFaculty of Life Sciences and Medicine, King’s College London, London, UK; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-8046-730X
ORCID Icon,
Miguel Sequeira CamposFaculty of Life Sciences and Medicine, King’s College London, London, UK; ORCID Iconhttp://orcid.org/0000-0001-5751-6516
ORCID Icon &
Mohsen El-SayedDepartment of Obstetrics and Gynaecology, Darent Valley Hospital, Dartford, UK
Pages 573-574 | Published online: 01 Aug 2019

References

  • Cowett RM, Hakanson DO, Kocon RW, Oh W. 1976. Untoward neonatal effect of intraamniotic administration of methylene blue. Obstetrics and Gynecology 48:74S–75S.
  • Gerli S, Rossetti D, Unfer V, Di Renzo GC. 2004. Laparoscopy and methylene blue intrauterine injection immediately after undiagnosed conception: effect on pregnancy and neonatal outcome. European Journal of Obstetrics, Gynecology, and Reproductive Biology 112:102–103.
  • Greene DN, Schmidt RL, Kamer SM, Grenache DG, Hoke C, Lorey TS. 2013. Limitations in qualitative point of care hCG tests for detecting early pregnancy. Clinica Chimica Acta 415:317–321.
  • Ireland KE, Rodriguez EI, Acosta OM, Ramsey PS. 2017. Intra-amniotic Dye Alternatives for the Diagnosis of Preterm Prelabor Rupture of Membranes. Obstetrics and Gynecology 129: 1040–1045.
  • Katz Z, Lancet M. 1981. Inadvertent intrauterine injection of methylene blue in early pregnancy. The New England Journal of Medicine 304: 1427.
  • Kidd SA, Lancaster PAL, Anderson JC, Boogert A, Fisher Coll, Robertson R, et al. 1996. Fetal death after exposure to methylene blue dye during mid-trimester amniocentesis in twin pregnancy. Prenatal Diagnosis 16:39–47.
  • Nicolini U, Monni G. 1990. Intestinal obstruction in babies exposed in utero to methylene blue. Lancet (London, England) 336:1258–1259.
  • Sirisena J, Lanerolle SD. 2000. A cautionary tale: intra-amniotic injection of methylene blue. The Ceylon Medical Journal 45:44–45.
  • Spahr RC, Salsburey DJ, Krissberg A, Prin W. 1980. Intraamniotic injection of methylene blue leading to methemoglobinemia in one of twins. International Journal of Gynaecology and Obstetrics: The Official Organ of the International Federation of Gynaecology and Obstetrics 17:477–478.
  • van der Pol JG, Wolf H, Boer K, Treffers PE, Leschot NJ, Hey HA, et al. 1992. Jejunal atresia related to the use of methylene blue in genetic amniocentesis in twins. British Journal of Obstetrics and Gynaecology 99:141–143.

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