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Research Article

Vascular effect of levonorgestrel intrauterine system on heavy menstrual bleeding: is it associated with hemodynamic changes in uterine, radial, and spiral arteries?

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References

  • Bastianelli C, Farris M, Rapiti S, Vecchio RB, Benagiano G. 2014. Different bleeding patterns with the use of levonorgestrel intrauterine system: are they associated with changes in uterine artery blood flow? Biomed Research International 2014:815127.
  • Cameron IT. 2001. The levonorgestrel intrauterine system: the benefits of reduced bleeding. The European Journal of Contraception and Reproductive Health Care 6:27–32.
  • Cihangir U, Ebru A, Murat E, Levent Y. 2013. Mechanism of action of the levonorgestrel-releasing intrauterine system in the treatment of heavy menstrual bleeding. International Journal of Gynaecology and Obstetrics 123:146–149.
  • Dane B, Akca A, Dane C, Evcimen S, Cetin A. 2009. Comparison of the effects of the levonorgestrel-releasing intrauterine system (Mirena) and depot-medroxyprogesterone acetate (Depo-Provera) on subendometrial microvascularisation and uterine artery blood flow. The European Journal of Contraception & Reproductive Health Care 14:240–244.
  • Haliloglu B, Celik A, Ilter E, Bozkurt S, Ozekici U. 2011. Comparison of uterine artery blood flow with levonorgestrel intrauterine system and copper intrauterine device. Contraception 83:578–581.
  • Higham JM, O'Brien PM, Shaw RW. 1990. Assessment of menstrual blood loss using a pictorial chart. British Journal of Obstetrics and Gynaecology 97:734–739.
  • Jarvela I, Raudaskoski T, Tekay A, Jouppila P. 1997. Effect of the levonorgestrel-releasing intrauterine system on the uterine artery pulsatility index in postmenopausal hormone replacement therapy. Ultrasound in Obstetrics and Gynecology 10:350–355.
  • Jarvela I, Tekay A, Jouppila P. 1998. The effect of a levonorgestrel-releasing intrauterine system on uterine artery blood flow, hormone concentrations and ovarian cyst formation in fertile women. Human Reproduction (Oxford, England) 13:3379–3383.
  • Jimenez MF, Arbo E, Vetori D, de Freitas FM, Cunha-Filho JS. 2008a. The effect of the levonorgestrel-releasing intrauterine system and the copper intrauterine device on subendometrial microvascularization and uterine artery blood flow. Fertility and Sterility 90:1574–1578.
  • Jimenez MF, Vetori D, Fagundes PA, de Freitas FM, Cunha-Filho JS. 2008b. Subendometrial microvascularization and uterine artery blood flow in IUD-induced side effects (levonorgestrel intrauterine system and copper intrauterine device). Contraception 78:324–327.
  • Jondet M, Letellier B, Verdys MT. 2005. Endometrial vascularization in levonorgestrel intrauterine device users; computerized microvessel measurement study. Contraception 71:60–64.
  • Jones RL, Critchley HO. 2000. Morphological and functional changes in human endometrium following intrauterine levonorgestrel delivery. Human Reproduction 15:162–172.
  • Kai J, Middleton L, Daniels J, Pattison H, Tryposkiadis K, Gupta J. 2016. Usual medical treatments or levonorgestrel-IUS for women with heavy menstrual bleeding: long-term randomised pragmatic trial in primary care. The British Journal of General Practice 66:e861–e870.
  • Kucuk T, Ertan K. 2008. Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia: a randomized, prospective, controlled clinical trial in female smokers. Clinical and Experimental Obstetrics and Gynecology 35:57–60.
  • Lahteenmaki P, Haukkamaa M, Puolakka J, Riikonen U, Sainio S, Suvisaari J, et al. 1998. Open randomised study of use of levonorgestrel releasing intrauterine system as alternative to hysterectomy. Bmj (Clinical Research ed.) 316:1122–1126.
  • Mawet M, Nollevaux F, Nizet D, Wijzen F, Gordenne V, Tasev N, et al. 2014. Impact of a new levonorgestrel intrauterine system, Levosert((R)), on heavy menstrual bleeding: results of a one-year randomised controlled trial. The European Journal of Contraception & Reproductive Health Care 19:169–179.
  • Munro MG, Critchley HO, Fraser IS. 2012. The FIGO systems for nomenclature and classification of causes of abnormal uterine bleeding in the reproductive years: who needs them? American Journal of Obstetrics and Gynecology 207:259–265.
  • Pakarinen P, Luukkainen T, Laine H, Lahteenmaki P. 1995. The effect of local intrauterine levonorgestrel administration on endometrial thickness and uterine blood circulation. Human Reproduction (Oxford, England) 10:2390–2394.
  • Rezk M, Al-Halaby A, Emarh M, Shawky M. 2017. Correlation between uterine artery Doppler indices and menstrual irregularities among levonorgestrel releasing intrauterine system and depot medroxyprogesterone acetate users: a prospective observational study. The European Journal of Contraception and Reproductive Health Care 22:316–320.
  • Sivin I, Stern J, Coutinho E, Mattos CE, el Mahgoub S, Diaz S, et al. 1991. Prolonged intrauterine contraception: a seven-year randomized study of the levonorgestrel 20 mcg/day (LNg 20) and the Copper T380 Ag IUDS. Contraception 44:473–480.
  • Zalel Y, Gamzu R, Shulman A, Achiron R, Schiff G, Lidor A. 2003. The progestative effect of the levonorgestrel-releasing intrauterine system–when does it manifest? Contraception 67:473–476.
  • Zalel Y, Shulman A, Lidor A, Achiron R, Mashiach S, Gamzu R. 2002. The local progestational effect of the levonorgestrel-releasing intrauterine system: a sonographic and Doppler flow study. Human Reproduction (Oxford, England) 17:2878–2880.
  • Zhu PD, Luo HZ, Xu RH, Cheng J, Wu SC, Chen JH, et al. 1989. The effect of intrauterine devices, the stainless steel ring, the copper T220, and releasing levonorgestrel, on the bleeding profile and the morphological structure of the human endometrium-a comparative study of three IUDs. A morphometric study of 96 cases. Contraception 40:425–438.

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