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Original Articles: Gynaecology

Does LH supplementation in poor responders affect granulosa cells apoptosis rate in ART? A prospective randomised controlled trial

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References

  • Almeida CP, Ferreira MCF, Silveira CO, Campos JR, Borges IT, Baeta PG, et al. 2018. Clinical correlation of apoptosis in human granulosa cells-a review. Cell Biology International 42:1276–1281.
  • Alviggi C, Clarizia R, Mollo A, Ranieri A, De Placido G. 2006. Outlook: who needs LH in ovarian stimulation? Reproductive Biomedicine Online 12:599–607.
  • Alviggi C, Clarizia R, Pettersson K, Mollo A, Humaidan P, Strina I, et al. 2009. Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism. Reproductive Biomedicine Online 18:9–14.
  • Alviggi C, Conforti A, Esteves SC, Andersen CY, Bosch E, Buhler K, et al. 2018. Recombinant luteinizing hormone supplementation in assisted reproductive technology: a systematic review. Fertility and Sterility 109:644–664.
  • Alviggi C, Pettersson K, Longobardi S, Andersen CY, Conforti A, De Rosa P, et al. 2013. A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology. Reproductive Biology and Endocrinology 11:51.
  • Amsterdam A, Sasson R, Keren-Tal I, Aharoni D, Dantes A, Rimon E, et al. 2003. Alternative pathways of ovarian apoptosis: death for life. Biochemical Pharmacology 66:1355–1362.
  • Bosco L, Ruvolo G, Morici G, Manno M, Cittadini E, Roccheri MC. 2005. Apoptosis in human unfertilized oocytes after intracytoplasmic sperm injection. Fertility and Sterility 84:1417–1423.
  • Fan Y, Chang Y, Wei L, Chen J, Li J, Goldsmith S, et al. 2019. Apoptosis of mural granulosa cells is increased in women with diminished ovarian reserve. Journal of Assisted Reproduction and Genetics 36:1225–1235.
  • Ferraretti AP, La Marca A, Fauser BC, Tarlatzis B, Nargund G, Gianaroli L. 2011. ESHRE consensus on the definition of ‘poor response’ to ovarian stimulation for in vitro fertilization: the Bologna criteria. Human Reproduction 26:1616–1624.
  • Hattori K, Orisaka M, Fukuda S, Tajima K, Yamazaki Y, Mizutani T, et al. 2018. Luteinizing hormone facilitates antral follicular maturation and survival via thecal paracrine signaling in cattle. Endocrinology 159:2337–2347.
  • Humaidan P, Chin W, Rogoff D, D’Hooghe T, Longobardi S, Hubbard J, et al. 2017. Efficacy and safety of follitropin alfa/lutropin alfa in ART: a randomized controlled trial in poor ovarian responders. Human Reproduction 32:544–555.
  • Jeppesen JV, Kristensen SG, Nielsen ME, Humaidan P, Dal Canto M, Fadini R, et al. 2012. LH-receptor gene expression in human granulosa and cumulus cells from antral and preovulatory follicles. The Journal of Clinical Endocrinology and Metabolism 97:E1524–E1531.
  • Lee KS, Joo BS, Na YJ, Yoon MS, Choi OH, Kim WW. 2001. Cumulus cells apoptosis as an indicator to predict the quality of oocytes and the outcome of IVF-ET. Journal of Assisted Reproduction and Genetics 18:490–498.
  • Lehert P, Kolibianakis EM, Venetis CA, Schertz J, Saunders H, Arriagada P, et al. 2014. Recombinant human follicle-stimulating hormone (r-hFSH) plus recombinant luteinizing hormone versus r-hFSH alone for ovarian stimulation during assisted reproductive technology: systematic review and meta-analysis. Reproductive Biology and Endocrinology 12:17.
  • Majtnerova P, Rousar T. 2018. An overview of apoptosis assays detecting DNA fragmentation. Molecular Biology Reports 45:1469–1478.
  • Nakahara K, Saito H, Saito T, Ito M, Ohta N, Sakai N, et al. 1997. Incidence of apoptotic bodies in membrana granulosa of the patients participating in an in vitro fertilization program. Fertility and Sterility 67:302–308.
  • Oosterhuis GJ, Michgelsen HW, Lambalk CB, Schoemaker J, Vermes I. 1998. Apoptotic cell death in human granulosa-lutein cells: a possible indicator of in vitro fertilization outcome. Fertility and Sterility 70:747–749.
  • Orisaka M, Hattori K, Fukuda S, Mizutani T, Miyamoto K, Sato T, et al. 2013. Dysregulation of ovarian follicular development in female rat: LH decreases FSH sensitivity during preantral-early antral transition. Endocrinology 154:2870–2880.
  • Regan SLP, Knight PG, Yovich JL, Leung Y, Arfuso F, Dharmarajan A. 2018. Granulosa cell apoptosis in the ovarian follicle-a changing view. Front Endocrinol 9:61.
  • Regan SLP, Knight PG, Yovich JL, Stanger JD, Leung Y, Arfuso F, et al. 2018. The effect of ovarian reserve and receptor signalling on granulosa cell apoptosis during human follicle development. Molecular and Cellular Endocrinology 470:219–227.
  • Ruvolo G, Bosco L, Pane A, Morici G, Cittadini E, Roccheri MC. 2007. Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures. Fertility and Sterility 87:542–546.
  • Sifer C, Benifla JL, Bringuier AF, Porcher R, Blanc-Layrac G, Madelenat P, et al. 2002. Could induced apoptosis of human granulosa cells predict in vitro fertilization-embryo transfer outcome? A preliminary study of 25 women. European Journal of Obstetrics & Gynecology and Reproductive Biology 103:150–153.
  • van Engeland M, Nieland LJ, Ramaekers FC, Schutte B, Reutelingsperger CP. 1998. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31:1–9.

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