220
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

The first report of clonidine in vivo/in vitro effects on infertile women with polycystic ovary syndrome (in vivo/in vitro study)

ORCID Icon, , , , &

References

  • Barel E, Abu-Shkara R, Colodner R, Masalha R, Mahagna L, Zemel OC, et al. 2018. Gonadal hormones modulate the HPA-axis and the SNS in response to psychosocial stress. Journal of Neuroscience Research 96:1388–1397.
  • Barron ML. 2007. Light exposure, melatonin secretion, and menstrual cycle parameters: an integrative review. Biological Research for Nursing 9:49–69.
  • Basheer M, Rai S, Ghosh H, Ahmad Hajam Y. 2018. Therapeutic efficacy of melatonin against polycystic ovary syndrome (PCOS) induced by letrozole in wistar rat. Pakistan Journal of Biological Sciences 21:340–347.
  • Bexis S, Docherty JR. 2005. Role of alpha2A-adrenoceptors in the effects of MDMA on body temperature in the mouse. British Journal of Pharmacology 146:1–6.
  • Bjorntorp P, Rosmond R. 2000. Neuroendocrine abnormalities in visceral obesity. International Journal of Obesity Supplements 2:S80–S85.
  • Calogero AE, Gallucci WT, Chrousos GP, Gold PW. 1988. Catecholamine effects upon rat hypothalamic corticotropin-releasing hormone secretion in vitro. The Journal of Clinical Investigation 82:839–846.
  • Calvey TN, Williams NE. Principles and practice of pharmacology for anaesthetists. 4th ed. Oxford (UK): Blackwell Science Ltd; 2003.
  • Dag ZO, Alpua M, Turkel Y, Isik Y. 2015. Autonomic dysfunction in patients with polycystic ovary syndrome. Taiwanese Journal of Obstetrics & Gynecology 54:381–384.
  • Doi SAR, Towers PA, Scott CJ, Al-Shoumer KAS. 2005. PCOS: an ovarian disorder that leads to dysregulation in the hypothalamic-pituitary-adrenal axis? European Journal of Obstetrics, Gynecology, and Reproductive Biology 118:4–16.
  • Dokras A, Clifton S, Futterweit W, Wild R. 2012. Increased prevalence of anxiety symptoms in women with polycystic ovary syndrome: systematic review and meta-analysis. Fertility and Sterility 97:225–230.
  • Foldes A, Maxwell CA, Hinks NT, Hoskinson RM, Scaramuzzi RJ. 1982. Effects of steroids on beta-adrenergic binding sites in sheep pineal glands. Biochemical Pharmacology 31:1369–1374.
  • Gordon JL, Girdler SS, Meltzer-Brody SE, Stika CS, Thurston RC, Clark CT, et al. 2015. Ovarian hormone fluctuation, neurosteroids, and HPA axis dysregulation in perimenopausal depression: a novel heuristic model. The American Journal of Psychiatry 172:227–236.
  • Hall JE, Uhrich TU, Ebert TJ. 2001. Sedative, analgesic and cognitive effects of clonidine infusions in humans. British Journal of Anaesthesia 86:5–11.
  • Handa RJ, Mani SK, Uht RM. 2012. Estrogen receptors and the regulation of neural stress responses. Neuroendocrinology 96:111–118.
  • Hobson JA, Pace-Schott EF. 2002. The cognitive neuroscience of sleep: neuronal systems, consciousness and learning. Nature Reviews. Neuroscience 3:679–693.
  • Kalsbeek A, van der Spek R, Lei J, Endert E, Buijs RM, Fliers E. 2012. Circadian rhythms in the hypothalamo-pituitary-adrenal (HPA) axis. Molecular and Cellular Endocrinology 349:20–29.
  • Kellner M, Yassouridis A, Manz B, Steiger A, Holsboer F, Wiedemann K. 1997. Corticotropin-releasing hormone inhibits melatonin secretion in healthy volunteers – a potential link to low-melatonin syndrome in depression? Neuroendocrinology 65:284–290.
  • Kumar A, Maitra S, Khanna P, Baidya DK. 2014. Clonidine for management of chronic pain: a brief review of the current evidences. Saudi Journal of Anaesthesia 8:92–96.
  • Lansdown A, Rees DA. 2012. The sympathetic nervous system in polycystic ovary syndrome: a novel therapeutic target? Clinical Endocrinology 77:791–801.
  • Lansdown AJ, Warnert EAH, Sverrisdóttir Y, Wise RG, Rees DA. 2019. Regional cerebral activation accompanies sympathoexcitation in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism 104:3614–3623.
  • Lara HE, Porcile A, Espinoza J, Romero C, Luza SM, Fuhrer J, et al. 2001. Release of norepinephrine from the human ovary. Coupling to the steroidogenic response. Endocrinology 15:187–192.
  • Leśniewska B, Miśkowiak B, Nowak M, Malendowicz LK. 1990. Sex differences in adrenocortical structure and function. XXVII. The effect of ether stress on ACTH and corticosterone in intact, gonadectomized, and testosterone- or estradiol-replaced rats. Research in Experimental Medicine. Zeitschrift Fur Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie 190:95–103.
  • Levy BH, Tasker JG. 2012. Synaptic regulation of the hypothalamic-pituitary-adrenal axis and its modulation by glucocorticoids and stress. Frontiers in Cellular Neuroscience 6:24.
  • Mitchell A, Bührmann S, Saez AO, Rushentsova U, Schäfers RF, Philipp T, Nürnberger J. 2005. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovascular Drugs and Therapy 19:49–55.
  • Mitchell A, Weinshenker D. 2010. Good night and good luck: norepinephrine in sleep pharmacology. Biochemical Pharmacology 79:801–809.
  • Mokhtari F, Akbari Asbagh F, Azmoodeh O, Bakhtiyari M, Almasi-Hashiani A. 2019. Effects of melatonin administration on chemical pregnancy rates of polycystic ovary syndrome patients undergoing intrauterine insemination: a randomized clinical trial. International Journal of Fertility and Sterility 13:225–229.
  • Muñóz-Hoyos A, Fernández-García JM, Molina-Carballo A, Macías M, Escames G, Ruiz-Cosano C, Acuña-Castroviejo D. 2000. Effect of clonidine on plasma ACTH, cortisol and melatonin in children. Journal of Pineal Research 29:48–53.
  • Neil MJ. 2011. Clonidine: clinical pharmacology and therapeutic use in pain management. Current Clinical Pharmacology 6:280–287.
  • Norman RL, Smith CJ, Pappas JD, Hall J. 1992. Exposure to ovarian steroids elicits a female pattern of plasma cortisol levels in castrated male macaques. Steroids 57:37–43.
  • Olsen DH, Ferin M. 1987. Corticotropin-releasing hormone inhibits gonadotropin secretion in ovariectomized rhesus monkey. Journal of Clinical Endocrinology and Metabolism 65:262–267.
  • Pelayo F, Dubocovich ML, Langer SZ. 1977. Regulation of noradrenaline release in the rat pineal through a negative feedback mechanism mediated by presynaptic alpha-adrenoceptors. European Journal of Pharmacology 45:317–318.
  • Pires-Lapa MA, Carvalho-Sousa CE, Cecon E, Fernandes PA, Fernandes PA, Markus RP. 2018. β-Adrenoceptors trigger melatonin synthesis in phagocytes. International Journal of Molecular Sciences 19:2182.
  • Raiteri M, Bonanno G, Maura G, Pende M, Andrioli GC, Ruelle A. 1992. Subclassification of release-regulating alpha 2-autoreceptors in human brain cortex. British Journal of Pharmacology 107:1146–1151.
  • Reiter RJ. 1998. Melatonin and human reproduction. Annals of Medicine 30:103–108.
  • Ricu M, Paredes A, Greiner M, Ojeda SR, Lara HE. 2008. Functional development of the ovarian noradrenergic innervation. Endocrinology 149:50–56.
  • Rosenfield RL, Ehrmann DA. 2016. The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited. Endocrine Reviews 37:467–520.
  • Rossi SP, Matzkin ME, Terradas C, Ponzio R, Puigdomenech E, Levalle O, et al. 2012. New insights into melatonin/CRH signaling in hamster Leydig cells. General and Comparative Endocrinology 178:153–163.
  • [ESHRE/ASRM] Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. 2004. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and Sterility 81:19–25.
  • Serova LI, Harris HA, Maharjan S, Sabban EL. 2010. Modulation of responses to stress by estradiol benzoate and selective estrogen receptor agonists. The Journal of Endocrinology 205:253–262.
  • Shimizu K. 1994. Effect of alpha 1- and alpha 2-adrenoceptor agonists and antagonists on ACTH secretion in intact and in hypothalamic deafferented rats. Journal of Pharmacology 36:23–33.
  • Stefanovic B, Spasojevic N, Jovanovic P, Ferizovic H, Ferizovic H, Dronjak S. 2018. Melatonin modulate the expression of α1- and β2-adrenoceptors in the hippocampus of rats subjected to unpredictable chronic mild stress. Bratislavske Lekarske Listy 119:429–433.
  • Stener-Victorin E, Ploj K, Larsson BM, Holmäng A. 2005. Rats with steroid-induced polycystic ovaries develops hypertension and increased sympathetic nervous system activity. Reproductive Biology and Endocrinology 7:44.
  • Szafarczyk A, Gaillet S, Barbanel G, Malaval F, Assenmacher I. 1990. Implication of alpha-2 adrenergic post-synaptic receptors in the central catecholaminergic stimulation of the corticotropic axis in rats. Comptes Rendus de L'Academie Des Sciences. Serie III, Sciences de la Vie 311:81–88.
  • Tofighi RA, Hassanzad A, Aryaie M. 2014. Oral clonidine premedication reduces postoperative pain in children. European Journal of Experimental Biology 4:102–105.
  • Veith RC, Best JD, Halte JB. 1984. Dose-dependent suppression of norepinephrine appearance rate in plasma by clonidine in man. The Journal of Clinical Endocrinology and Metabolism 59:151–155.
  • Wrzosek A, Woron J, Dobrogowski J, Jakowicka-Wordliczek J, Wordliczek J. 2015. Topical clonidine for neuropathic pain. The Cochrane Database of Systematic Reviews 8:CD010967.
  • Yang JH, Li LH, Lee S, Jo IH, Lee SY, Ryu PD. 2007. Effects of adrenalectomy on the excitability of neurosecretory parvocellular neurons in the hypothalamic paraventricular nucleus. Journal of Neuroendocrinology 19:293–301.
  • Yuwiller A. 1989. Effects of steroids on serotonin N-acetyltransferase activity of pineals in organ culture. Journal of Neurochemistry 52:46–53.
  • Zangeneh FZ, Mohammadi A, Ejtemaeimehr SH, Naghizadeh MM, Fatemeh A. 2011. The role of the opioid system and its interaction with the sympathetic nervous system in the processing of polycystic ovary syndrome modeling in the rat. Archives of Gynecology and Obstetrics 283:885–892.
  • Zangeneh FZ, Naghizadeh MM, Abdollahi A, Bagheri M. 2014. Synchrony between ovarian function and sleep in polycystic ovary syndrome patients. Open Journal of Obstetrics and Gynecology 4:725–731.
  • Zangeneh FZ, Naghizadeh MM, Bagheri M, Jafarabadi M. 2017. Are CRH & NGF as psychoneuroimmune regulators in women with polycystic ovary syndrome? Gynecological Endocrinology 33:227–233.
  • Zangeneh FZ, Tehraninejad E, Naghizadeh MM. 2016. Effect of alpha-2 adrenoceptor inhibitors on the growth of ovarian follicles in patients with polycystic ovary syndrome. Tehran University Medical Journal 73:709–716.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.