The therapeutic effects of coenzyme Q10 on surgically induced endometriosis in Sprague Dawley rats

References

• Aaseth J, Alexander J, Alehagen U. 2021. Coenzyme Q10 supplementation – in ageing and disease. Mechanisms of Ageing and Development 197:111521.
   PubMed Web of Science ®Google Scholar
• Abdi S, Montazeri V, Garjani A, Shayanfar A, Pirouzpanah S. 2020. Coenzyme Q10 in association with metabolism-related AMPK/PFKFB3 and angiogenic VEGF/VEGFR2 genes in breast cancer patients. Molecular Biology Reports 47:2459–2473.
   PubMed Web of Science ®Google Scholar
• Agarwal A, Aponte-Mellado A, Premkumar BJ, Shaman A, Gupta S. 2012. The effects of oxidative stress on female reproduction: a review. Reproductive Biology and Endocrinology 10:1–31.
   PubMed Web of Science ®Google Scholar
• Akkol EK, Demirel MA, Acıkara OB, Süntar I, Ergene B, Ilhan M, et al. 2015. Phytochemical analyses and effects of Alchemilla mollis (Buser) Rothm. and Alchemilla persica Rothm. in rat endometriosis model. Archives of Gynecology and Obstetrics 292:619–628.
   PubMed Web of Science ®Google Scholar
• Altintas D, Kokcu A, Tosun M, Cetinkaya MB, Kandemir B. 2008. Comparison of the effects of cetrorelix, a GnRH antagonist, and leuprolide, a GnRH agonist, on experimental endometriosis. Journal of Obstetrics and Gynaecology Research 34:1014–1019.
   PubMed Web of Science ®Google Scholar
• Amin MM, Asaad GF, Salam RMA, El-Abhar HS, Arbid MS. 2014. Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats. PLoS One 9:e89169.
   PubMed Web of Science ®Google Scholar
• Amuthan A, Anandh S, Musharraf S, Agarwal N, Devi V, Shenoy RP, Nayal B. 2015. Effect of Notchi kudineer (Vitex negundo aqueous extract) on surgically induced endometriosis in Sprague Dawley rats. International Journal of Pharmacology and Clinical Sciences 4:35–43.
   Google Scholar
• Asghari S, Valizadeh A, Aghebati-Maleki L, Nouri M, Yousefi M. 2018. Endometriosis: perspective, lights, and shadows of etiology. Biomedicine & Pharmacotherapy 106:163–174.
   PubMed Web of Science ®Google Scholar
• Bakacak M, Ercan Ö, Köstü B, Bostancı MS, İnanç F, Yaylalı A, et al. 2015. The effects of thalidomide in a rat model of surgically-induced endometriosis. Journal of Turkish Society of Obstetrics and Gynecology 12:125–131.
   PubMedGoogle Scholar
• Ben‐Meir A, Burstein E, Borrego‐Alvarez A, Chong J, Wong E, Yavorska T, et al. 2015. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell 14:887–895.
   PubMed Web of Science ®Google Scholar
• Blauer KL, Collins RL. 1988. The effect of intraperitoneal progesterone on postoperative adhesion formation in rabbits. Fertility and Sterility 49:144–149.
   PubMed Web of Science ®Google Scholar
• Brandão VCM, Meola J, Garcia SB, Candido-dos-Reis FJ, Poli-Neto OB, Nogueira AA, Rosa-e-Silva JC. 2018. Increased expression levels of metalloprotease, tissue inhibitor of metalloprotease, metallothionein, and p63 in ectopic endometrium: an animal experimental study. Revista brasileira de ginecologia e obstetricia 40:705–712.
   Web of Science ®Google Scholar
• Bulletti C, Coccia ME, Battistoni S, Borini A. 2010. Endometriosis and infertility. Journal of Assisted Reproduction and Genetics 27:441–447.
   PubMed Web of Science ®Google Scholar
• Bulun SE, Yilmaz BD, Sison C, Miyazaki K, Bernardi L, Liu S, et al. 2019. Endometriosis. Endocrine Reviews 40:1048–1079.
   PubMed Web of Science ®Google Scholar
• Carlyle D, Khader T, Lam D, Vadivelu N, Shiwlochan D, Yonghee C. 2020. Endometriosis pain management: a review. Current Pain and Headache Reports 24:1–9.
   PubMed Web of Science ®Google Scholar
• Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, et al. 2008. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition. 5:8.
   PubMed Web of Science ®Google Scholar
• Cora MC, Kooistra L, Travlos G. 2015. Vaginal cytology of the laboratory rat and mouse: review and criteria for the staging of the estrous cycle using stained vaginal smears. Toxicologic Pathology 43:776–793.
   PubMed Web of Science ®Google Scholar
• Cordaro M, Trovato Salinaro A, Siracusa R, D’Amico R, Impellizzeri D, Scuto M, et al. 2021. Hidrox® and endometriosis: biochemical evaluation of oxidative stress and pain. Antioxidants 10:720.
   Web of Science ®Google Scholar
• Demirel MA, Suntar I, Ilhan M, Keles H, Kupeli Akkol E. 2014. Experimental endometriosis remission in rats treated with Achillea biebersteinii Afan.: histopathological evaluation and determination of cytokine levels. European Journal of Obstetrics, Gynecology, and Reproductive Biology 175:172–177.
   PubMed Web of Science ®Google Scholar
• Di Paola R, Fusco R, Gugliandolo E, Crupi R, Evangelista M, Granese R, Cuzzocrea S. 2016. Co-micronized palmitoylethanolamide/polydatin treatment causes endometriotic lesion regression in a rodent model of surgically induced endometriosis. Frontiers in Pharmacology 7:382.
   PubMed Web of Science ®Google Scholar
• Eisalou MY, Farahpour MR. 2022. Effectiveness of gamma oryzanol on prevention of surgical induced endometriosis development in rat model. Scientific Reports 12.1:1–7.
   Web of Science ®Google Scholar
• Fouad AA, Al-Mulhim AS, Jresat I. 2013. Therapeutic effect of coenzyme Q10 against experimentally-induced hepatocellular carcinoma in rats. Environmental Toxicology and Pharmacology 35:100–108.
   PubMed Web of Science ®Google Scholar
• Giannubilo SR, Orlando P, Silvestri S, Cirilli I, Marcheggiani F, Ciavattini A, Tiano L. 2018. CoQ10 supplementation in patients undergoing IVF-ET: the relationship with follicular fluid content and oocyte maturity. Antioxidants 7:141.
   Web of Science ®Google Scholar
• Griffioen AW, Molema G. 2000. Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacological Reviews 52:237–268.
   PubMed Web of Science ®Google Scholar
• Hargreaves I. 2014. Coenzyme Q10 as a therapy for mitochondrial disease. İnternational Journal of Biochemistry & Cell Biology 49:105–111.
   PubMedGoogle Scholar
• Ibrahim Abd El-Fadil Sehsah F, Taha Abd El-Fattah A, Mohammed Saeed A. 2022. The role of antioxidant supplementation in reducing the endometriosis related chronic pelvic pain in women. Al-Azhar Medical Journal 51.1:121–134.
   Google Scholar
• Ilhan M, Ali Z, Khan IA, Taştan H, Akkol EK. 2019. Bioactivity-guided isolation of flavonoids from Urtica dioica L. and their effect on endometriosis rat model. Journal of Ethnopharmacology 243:112100.
   PubMed Web of Science ®Google Scholar
• Jhun J, Lee SH, Byun J-K, Jeong J-H, Kim E-K, Lee J, et al. 2015. Coenzyme Q10 suppresses Th17 cells and osteoclast differentiation and ameliorates experimental autoimmune arthritis mice. Immunology Letters 166:92–102.
   PubMed Web of Science ®Google Scholar
• Ke J, Ye J, Li M, Zhu Z. 2021. The role of matrix metalloproteinases in endometriosis: a potential target. Biomolecules 11.11:1739.
   Web of Science ®Google Scholar
• Keenan JA, Williams-Boyce PK, Massey PJ, Chen TT, Caudle MR, Bukovsky A. 1999. Regression of endometrial explants in a rat model of endometriosis treated with the immune modulators loxoribine and levamisole. Fertility and Sterility 72:135–141.
   PubMed Web of Science ®Google Scholar
• Kennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Greb R, et al.; ESHRE Special Interest Group for Endometriosis and Endometrium Guideline Development Group. 2005. ESHRE guideline for the diagnosis and treatment of endometriosis. Human Reproduction 20:2698–2704.
   PubMed Web of Science ®Google Scholar
• Kimber-Trojnar Ż, Dłuski DF, Wierzchowska-Opoka M, Ruszała M, Leszczyńska-Gorzelak B. 2022. Metformin as a potential treatment option for endometriosis. Cancers 14:577.
   PubMed Web of Science ®Google Scholar
• Kodarahmian M, Amidi F, Moini A, Kashani L, Nashtaei MS, Pazhohan A, et al. 2019. The modulating effects of resveratrol on the expression of MMP-2 and MMP-9 in endometriosis women: a randomized exploratory trial. Gynecological Endocrinology 35:719–726.
   PubMed Web of Science ®Google Scholar
• Kunitomo M, Yamaguchi Y, Kagota S, Otsubo K. 2008. Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome. Journal of Pharmacological Sciences 107:128–137.
   PubMed Web of Science ®Google Scholar
• Lebovic DI, Kir M, Casey CL. 2004. Peroxisome proliferator–activated receptor-gamma induces regression of endometrial explants in a rat model of endometriosis. Fertility and Sterility 82:1008–1013.
   PubMed Web of Science ®Google Scholar
• Lin Y-H, Chen Y-H, Chang H-Y, Au H-K, Tzeng C-R, Huang Y-H. 2018. Chronic niche inflammation in endometriosis-associated infertility: current understanding and future therapeutic strategies. International Journal of Molecular Sciences 19.8:2385.
   Web of Science ®Google Scholar
• Liu H-T, Huang Y-C, Cheng S-B, Huang Y-T, Lin P-T. 2015. Effects of coenzyme Q10 supplementation on antioxidant capacity and inflammation in hepatocellular carcinoma patients after surgery: a randomized, placebo-controlled trial. Nutrition Journal 15:1–9.
   Web of Science ®Google Scholar
• Machado DE, Rodrigues-Baptista KC, Alessandra-Perini J, Soares de Moura R, Santos TAd, Pereira KG, et al. 2016. Euterpe oleracea extract (Açaí) is a promising novel pharmacological therapeutic treatment for experimental endometriosis. PLoS One 11:e0166059.
   PubMed Web of Science ®Google Scholar
• Melekoglu R, Ciftci O, Eraslan S, Cetin A, Basak N. 2018. The beneficial effects of nerolidol and hesperidin on surgically induced endometriosis in a rat model. Gynecological Endocrinology 34:975–980.
   PubMed Web of Science ®Google Scholar
• Nahari E, Razi M. 2018. Silymarin amplifies apoptosis in ectopic endometrial tissue in rats with endometriosis; implication on growth factor GDNF, ERK1/2 and Bcl-6b expression. Acta Histochemica 120:757–767.
   PubMed Web of Science ®Google Scholar
• Özel Ş, Süntar İ, Gökay NE, Türkmenoğlu TT, Demırel MA. 2020. The effectiveness of Teucrium chamaedrys L. extracts on endometriotic implant regression in rat endometriosis model. In: Veterinary research forum. Vol. 11, No. 4. Urmia (Iran): Faculty of Veterinary Medicine, Urmia University. p. 305.
   Google Scholar
• Pellicer N, Galliano D, Herraiz S, Bagger YZ, Arce JC, Pellicer A. 2021. Use of dopamine agonists to target angiogenesis in women with endometriosis. Human Reproduction 36:850–858.
   PubMed Web of Science ®Google Scholar
• Perez-Sanchez C, Ruiz-Limon P, Aguirre MA, Bertolaccini ML, Khamashta MA, Rodriguez-Ariza A, et al. 2017. Medical management of endometriosis. Clinical Obstetrics and Gynecology 60:485–496.
   PubMed Web of Science ®Google Scholar
• Rafique S, Decherney AH. 2017. Medical management of endometriosis. Clinical Obstetrics and Gynecology 60(3):485.
   Google Scholar
• Rahmani E, Jamilian M, Samimi M, Zarezade Mehrizi M, Aghadavod E, Akbari E, et al. 2018. The effects of coenzyme Q10 supplementation on gene expression related to insulin, lipid and inflammation in patients with polycystic ovary syndrome. Gynecological Endocrinology 34:217–222.
   PubMed Web of Science ®Google Scholar
• Roberts RA, Laskin DL, Smith CV, Robertson FM, Allen EM, Doorn JA, Slikker W. 2009. Nitrative and oxidative stress in toxicology and disease. Toxicological Sciences 112:4–16.
   PubMed Web of Science ®Google Scholar
• Scutiero G, Iannone P, Bernardi G, Bonaccorsi G, Spadaro S, Volta CA, et al. 2017. Oxidative stress and endometriosis: a systematic review of the literature. Oxidative Medicine and Cellular Longevity 2017:1–7.
   Web of Science ®Google Scholar
• Soares SR, Martínez-Varea A, Hidalgo-Mora JJ, Pellicer A. 2012. Pharmacologic therapies in endometriosis: a systematic review. Fertility and Sterility 98:529–555.
   PubMed Web of Science ®Google Scholar
• Suardika A, Pemayun TGA. 2018. New insights on the pathogenesis of endometriosis and novel non-surgical therapies. Journal of the Turkish-German Gynecological Association 19:158–164.
   PubMed Web of Science ®Google Scholar
• Talebi H, Farahpour MR, Hamishehkar H. 2021. The effectiveness of Rutin for prevention of surgical induced endometriosis development in a rat model. Scientific Reports 11:1–7.
   PubMed Web of Science ®Google Scholar
• Taylor HS, Adamson GD, Diamond MP, Goldstein SR, Horne AW, Missmer SA, et al. 2018. An evidence-based approach to assessing surgical versus clinical diagnosis of symptomatic endometriosis. International Journal of Gynecology & Obstetrics 142:131–142.
   PubMed Web of Science ®Google Scholar
• Testai L, Martelli A, Flori L, Cicero AF, Colletti A. 2021. Coenzyme Q10: clinical applications beyond cardiovascular diseases. Nutrients 13:1697.
   PubMed Web of Science ®Google Scholar
• Turk R, Koledić M, Maćešić N, Benić M, Dobranić V, Đuričić D, et al. 2017. The role of oxidative stress and inflammatory response in the pathogenesis of mastitis in dairy cows. Mljekarstvo 67:91–101.
   Web of Science ®Google Scholar
• Umezawa M, Sakata C, Tanaka N, Tabata M, Takeda K, Ihara T, Sugamata M. 2011. Pathological study for the effects of in utero and postnatal exposure to diesel exhaust on a rat endometriosis model. Journal of Toxicological Sciences 36:493–498.
   PubMed Web of Science ®Google Scholar
• Vernon MW, Wilson EA. 1985. Studies on the surgical induction of endometriosis in the rat. Fertility and Sterility 44:684–694.
   PubMed Web of Science ®Google Scholar
• Yan D, Liu X, Guo S-W. 2019. The establishment of a mouse model of deep endometriosis. Human Reproduction 34:235–247.
   PubMed Web of Science ®Google Scholar
• Yuvaraj S, Premkumar VG, Shanthi P, Vijayasarathy K, Gangadaran SGD, Sachdanandam P. 2009. Effect of coenzyme Q 10, riboflavin and niacin on tamoxifen treated postmenopausal breast cancer women with special reference to blood chemistry profiles. Breast Cancer Research and Treatment 114:377–384.
   PubMed Web of Science ®Google Scholar
• Zahrooni N, Hosseini SA, Ahmadzadeh A, Angali KA, Assarehzadegan MA. 2019. The effect of coenzyme Q10 supplementation on vascular endothelial growth factor and serum levels of interleukin 6 and 8 in women with breast cancer: a double-blind, placebo-controlled. Therapeutics and Clinical Risk Management Volume 15:1403–1410.
   Web of Science ®Google Scholar
• Zhai J, Bo Y, Lu Y, Liu C, Zhang L. 2017. Effects of coenzyme Q10 on markers of inflammation: a systematic review and meta-analysis. PLoS One 12:e0170172.
   PubMed Web of Science ®Google Scholar
• Zhang L, Xiong W, Li N, Liu H, He H, Du Y, et al. 2017. Estrogen stabilizes hypoxia-inducible factor 1α through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis. Fertility and Sterility 107:439–447.
   PubMed Web of Science ®Google Scholar
• Zhang YP, Eber A, Yuan Y, Yang Z, Rodriguez Y, Levitt RC, et al. 2013. Prophylactic and antinociceptive effects of coenzyme Q10 on diabetic neuropathic pain in a mouse model of type 1 diabetes. Anesthesiology 118:945–954.
   PubMed Web of Science ®Google Scholar
• Zhu TH, Zou G, Ding SJ, Li TT, Zhu LB, Wang JZ, et al. 2019. Mast cell stabilizer ketotifen reduces hyperalgesia in a rodent model of surgically induced endometriosis. Journal of Pain Research 12:1359–1369.
   PubMed Web of Science ®Google Scholar
• Zondervan KT, Becker CM, Missmer SA. 2020. Endometriosis. New England Journal of Medicine 382:1244–1256.
   PubMed Web of Science ®Google Scholar