Phloroglucinol inhibits oxytocin-induced contraction in rat gastric circular muscle and uterine smooth muscle

References

• Annahazi, A., et al., 2014. Role of antispasmodics in the treatment of irritable bowel syndrome. World Journal of Gastroenterology, 20 (20), 6031–6043.
   PubMed Web of Science ®Google Scholar
• Asad, M., et al., 2001. Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. Life Sciences, 70 (1), 17–24.
   PubMed Web of Science ®Google Scholar
• Bjornsson, B., et al., 2006. The relationship of gastrointestinal symptoms and menstrual cycle phase in young healthy women. Laeknabladid, 92, 677–682.
   PubMedGoogle Scholar
• Blanchard, C., et al., 2018. Efficacy of phloroglucinol for treatment of abdominal pain: a systematic review of literature and meta-analysis of randomised controlled trials versus placebo. European Journal of Clinical Pharmacology, 74 (5), 541–548.
   PubMed Web of Science ®Google Scholar
• Clara, B., et al., 2020. Efficacy of phloroglucinol for the treatment of pain of gynaecologic or obstetrical origin: a systematic review of literature of randomised controlled trials. European Journal of Clinical Pharmacology, 76 (1), 1–6.
   PubMed Web of Science ®Google Scholar
• Davison, J.S., et al., 1983. The effects of atropine and secoverine on gastric secretion and motility in the mouse isolated stomach. British Journal of Pharmacology, 79 (2), 525–529.
   PubMed Web of Science ®Google Scholar
• De Sanctis, V., et al., 2016. Dysmenorrhea in adolescents and young adults: a review in different country. Acta Biomedica, 87, 233–246.
   PubMedGoogle Scholar
• Garriz, A., et al., 2021. Role of the phospholipase C pathway and calcium mobilization in oxytocin-induced contraction of lacrimal gland myoepithelial cells. Investigative Ophthalmology & Visual Science, 62 (14), 25.
   PubMed Web of Science ®Google Scholar
• Gimpl, G. and Fahrenholz, F., 2001. The oxytocin receptor system: structure, function, and regulation. Physiological Reviews, 81 (2), 629–683.
   PubMed Web of Science ®Google Scholar
• Huang, L., et al., 2016. Effect of Alpinia officinarum Hance alcohol extracts on primary dysmenorrheal. Asian Pacific Journal of Tropical Medicine, 9 (9), 882–886.
   PubMed Web of Science ®Google Scholar
• Huang, Y.J., et al., 2021. Ethanolic extracts of adlay testa and hull and their active biomolecules exert relaxing effect on uterine muscle contraction through blocking extracellular calcium influx in ex vivo and in vivo studies. Biomolecules, 11 (6), 887.
   PubMed Web of Science ®Google Scholar
• Ju, H., Jones, M. and Mishra, G., 2014. The prevalence and risk factors of dysmenorrhea. Epidemiologic Reviews, 36, 104–113.
   PubMed Web of Science ®Google Scholar
• Li, L., et al., 2007. Systemic oxytocin and vasopressin excite gastrointestinal motility through oxytocin receptor in rabbits. Neurogastroenterology and Motility, 19 (10), 839–844.
   PubMed Web of Science ®Google Scholar
• Li, N.S., et al., 2011. Phloroglucinol protects gastric mucosa against ethanol-induced injury through regulating myeloperoxidase and catalase activities. Fundamental & Clinical Pharmacology, 25 (4), 462–468.
   PubMed Web of Science ®Google Scholar
• Li, W.J., et al., 2021. PGE2 vs PGF2alpha in human parturition. Placenta, 104, 208–219.
   PubMed Web of Science ®Google Scholar
• Liu, C.Y., et al., 2003. Endogenous oxytocin excites phasic contraction of gallbladder in rabbits through oxytocin receptor. Chinese Journal of Physiology, 46, 95–101.
   PubMed Web of Science ®Google Scholar
• Liu, J., et al., 2017. Altered white matter microarchitecture in the cingulum bundle in women with primary dysmenorrhea: a tract-based analysis study. Human Brain Mapping, 38 (9), 4430–4443.
   PubMed Web of Science ®Google Scholar
• Ohlsson, B., et al., 2004. Oxytocin stimulates colonic motor activity in healthy women. Neurogastroenterology and Motility, 16 (2), 233–240.
   PubMed Web of Science ®Google Scholar
• Olson, D.M., 2003. The role of prostaglandins in the initiation of parturition. Best Practice & Research. Clinical Obstetrics & Gynaecology, 17 (5), 717–730.
   PubMed Web of Science ®Google Scholar
• Park, S.J., et al., 2011. Phloroglucinol (PG) purified from Ecklonia cava attenuates radiation-induced apoptosis in blood lymphocytes and splenocytes. Food and Chemical Toxicology, 49 (9), 2236–2242.
   PubMed Web of Science ®Google Scholar
• Rodrigues, A.C., et al., 2011. Dysmenorrhea in adolescents and young adults: prevalence, related factors and limitations in daily living. Acta Medica Portuguesa, 24 (Suppl 2), 383–388. [quiz 389–392].
   PubMedGoogle Scholar
• Takeuchi, K., 2012. Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility. World Journal of Gastroenterology, 18 (18), 2147–2160.
   PubMed Web of Science ®Google Scholar
• Wang, R., et al., 2016. Role of the nitrergic pathway in motor effects of oxytocin in rat proximal colon. Neurogastroenterology and Motility, 28 (12), 1815–1823.
   PubMed Web of Science ®Google Scholar
• Wang, R., et al., 2017. Inhibitory action of oxytocin on spontaneous contraction of rat distal colon by nitrergic mechanism: involvement of cyclic GMP and apamin-sensitive K(+) channels. Acta Physiologica (Oxford, England), 221 (3), 182–192.
   PubMed Web of Science ®Google Scholar
• Wei, Y., et al., 2018. Extracts of compound Muniziqi granule suppressed uterus contraction and ameliorated oxytocin-induced primary dysmenorrhea. Journal of Ethnopharmacology, 223, 33–40.
   PubMed Web of Science ®Google Scholar
• Wu, C.L., et al., 2003. Pharmacological effects of oxytocin on gastric emptying and intestinal transit of a non-nutritive liquid meal in female rats. Naunyn-Schmiedeberg’s Archives of Pharmacology, 367 (4), 406–413.
   PubMed Web of Science ®Google Scholar
• Wu, F., Chen, Y. and Zheng, C., 2021. Efficacy of phloroglucinol for acceleration of labour: a systematic review and metaanalysis. Archives of Gynecology and Obstetrics, 304 (2), 421–428.
   PubMed Web of Science ®Google Scholar
• Xi, T.F., et al., 2019. Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway. Biochemical and Biophysical Research Communications, 508 (3), 959–964.
   PubMed Web of Science ®Google Scholar
• Xiao, H., et al., 2019. Mechanism of penehyclidine hydrochloride on a dysmenorrhea rat model. Drug Development Research, 80 (3), 325–332.
   PubMed Web of Science ®Google Scholar
• Xie, D.P., et al., 2003. Effect of oxytocin on contraction of rabbit proximal colon in vitro. World Journal of Gastroenterology, 9 (1), 165–168.
   PubMed Web of Science ®Google Scholar
• Yang, L., et al., 2015. An in vivo mouse model of primary dysmenorrhea. Experimental Animals, 64 (3), 295–303.
   PubMed Web of Science ®Google Scholar
• Yang, L., et al., 2016. Ge-Gen Decoction attenuates oxytocin-induced uterine contraction and writhing response: potential application in primary dysmenorrhea therapy. Chinese Journal of Natural Medicines, 14 (2), 124–132.
   PubMed Web of Science ®Google Scholar
• Yarmolinskaya, M., et al., 2020. The potentialities of oxytocin receptor inhibitors for endometriosis therapy. Gynecological Endocrinology, 36 (sup1), 16–19.
   PubMed Web of Science ®Google Scholar
• Zingg, H.H. and Laporte, S.A., 2003. The oxytocin receptor. Trends in Endocrinology and Metabolism: TEM, 14 (5), 222–227.
   PubMed Web of Science ®Google Scholar