1,742
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B/mechanistic target of rapamycin kinase signalling pathway

, , &
Article: 2151353 | Received 12 Aug 2022, Accepted 21 Nov 2022, Published online: 06 Jan 2023

References

  • Cadenas, C., et al., 2019. LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer. International Journal of Cancer, 145 (4), 901–915.
  • Chen, Q., et al., 2021. MicroRNA-148a-3p inhibits the proliferation of cervical cancer cells by regulating the expression levels of DNMT1 and UTF1. Oncology Letters, 22 (2), 617.
  • Cheng, X., et al., 2022. Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer. PLoS Genetics, 18 (2), e1010050.
  • Criscuolo, D., et al., 2020. Cholesterol homeostasis modulates platinum sensitivity in human ovarian cancer. Cells, 9 (4), 828. pp.
  • DA, S.J., et al., 2022. Upregulated miRNAs on the TP53 and RB1 binding seedless regions in high-risk HPV-associated penile cancer. Frontiers in Genetics, 13, 875939.
  • Gago-Dominguez, M., et al., 2021. LIPG endothelial lipase and breast cancer risk by subtypes. Scientific Reports, 11 (1), 10436.
  • Han, M.S., et al., 2018. Human papillomavirus 16 oncoproteins downregulate the expression of miR-148a-3p, miR-190a-5p, and miR-199b-5p in cervical cancer. BioMed Research International, 2018, 1942867.
  • Hunter, T., Ling, N. and Cooper, J.A., 1984. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature, 311 (5985), 480–483.
  • Jaye, M., et al., 1999. A novel endothelial-derived lipase that modulates HDL metabolism. Nature Genetics, 21 (4), 424–428.
  • Kousar, K., et al., 2022. Review article: immune landscape and immunotherapy options in cervical carcinoma. Cancers, 14 (18), 4458.
  • Laszlo, B., et al., 2021. Coordinated action of human papillomavirus type 16 E6 and E7 oncoproteins on competitive endogenous RNA (ceRNA) network members in primary human keratinocytes. BMC Cancer, 21 (1), 673.
  • Livak, K.J. and Schmittgen, T.D., 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25 (4), 402–408.
  • Lo, P.K., Yao, Y. and Zhou, Q., 2020. Inhibition of LIPG phospholipase activity suppresses tumor formation of human basal-like triple-negative breast cancer. Scientific Reports, 10 (1), 8911.
  • Lo, P.K., et al., 2018. LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer. eLife, 7, e31334.
  • Staubs, P.A., et al., 1998. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport. The Journal of Biological Chemistry, 273 (39), 25139–25147.
  • World Health Organization 2020, 2021. Cancer Today. https://gco.iarc.fr/today/home [Accessed January 11, 2021].
  • Xu, J., et al., 2021. Association of three micro-RNA gene polymorphisms with the risk of cervical cancer: a meta-analysis and systematic review. World Journal of Surgical Oncology, 19 (1), 346.
  • Zhang, W., et al., 2019. The exosome-mediated PI3k/Akt/mTOR signaling pathway in cervical cancer. International Journal of Clinical and Experimental Pathology, 12 (7), 2474–2484.