Septin9 DNA methylation as a promising biomarker for cervical cancer

References

• Bannaga, A.S., et al., 2021. Role of methylated septin 9 as an adjunct diagnostic and prognostic biomarker in hepatocellular carcinoma. HPB (Oxford), 23 (10), 1595–1606.
   PubMed Web of Science ®Google Scholar
• Bettegowda, C., et al., 2014. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine, 6 (224), 224r.
   Web of Science ®Google Scholar
• Bogani, G., et al., 2021. High-risk HPV-positive and -negative high-grade cervical dysplasia: Analysis of 5-year outcomes. Gynecologic Oncology, 161 (1), 173–178.
   PubMed Web of Science ®Google Scholar
• Bonde, J., et al., 2021. Methylation markers FAM19A4 and miR124-2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study. International Journal of Cancer, 148 (2), 396–405.
   PubMed Web of Science ®Google Scholar
• Bornstein, J., et al., 2012. 2011 colposcopic terminology of the International Federation for Cervical Pathology and Colposcopy. Obstetrics and Gynecology, 120 (1), 166–172.
   PubMed Web of Science ®Google Scholar
• Branchi, V., et al., 2016. Promoter hypermethylation of SHOX2 and SEPT9 is a potential biomarker for minimally invasive diagnosis in adenocarcinomas of the biliary tract. Clinical Epigenetics, 8, 133.
   PubMed Web of Science ®Google Scholar
• Bray, F., et al., 2018. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68 (6), 394–424.
   PubMed Web of Science ®Google Scholar
• Bu, Q., et al., 2018. The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women. BMC Cancer, 18 (1), 1182.
   PubMed Web of Science ®Google Scholar
• Cheng-Yen Lai, J., et al., 2018. The role of sentinel lymph node biopsy in early-stage cervical cancer: A systematic review. Taiwanese Journal of Obstetrics & Gynecology, 57 (5), 627–635.
   PubMed Web of Science ®Google Scholar
• Clarke, M.A., et al., 2017. Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer. International Journal of Cancer, 141 (4), 701–710.
   PubMed Web of Science ®Google Scholar
• Cohen, J.D., et al., 2017. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proceedings of the National Academy of Sciences of the United States of America, 114 (38), 10202–10207.
   PubMed Web of Science ®Google Scholar
• Connolly, D., et al., 2011. Septin roles in tumorigenesis. Biological Chemistry, 392 (8–9), 725–738.
   PubMed Web of Science ®Google Scholar
• Dasari, S., Wudayagiri, R. and Valluru, L., 2015. Cervical cancer: Biomarkers for diagnosis and treatment. Clinica Chimica Acta: International Journal of Clinical Chemistry, 445, 7–11.
   PubMed Web of Science ®Google Scholar
• De Strooper, L., et al., 2018. Cervical cancer risk in HPV-positive women after a negative FAM19A4/mir124-2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow-up. International Journal of Cancer, 143 (6), 1541–1548.
   PubMed Web of Science ®Google Scholar
• De Strooper, L.M., et al., 2014. Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2/3 lesions. Cancer Prevention Research (Philadelphia, PA), 7 (12), 1251–1257.
   PubMed Web of Science ®Google Scholar
• Dick, S., et al., 2019. Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis. Gynecologic Oncology, 154 (2), 368–373.
   PubMed Web of Science ®Google Scholar
• Diehl, F., et al., 2005. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America, 102 (45), 16368–16373.
   PubMed Web of Science ®Google Scholar
• Jiao, X., et al., 2019. Promoter methylation of SEPT9 as a potential biomarker for early detection of cervical cancer and its overexpression predicts radioresistance. Clinical Epigenetics, 11 (1), 120.
   PubMed Web of Science ®Google Scholar
• Kremer, W.W., et al., 2022. Clinical regression of high-grade cervical intraepithelial neoplasia is associated with absence of FAM19A4/miR124-2 DNA methylation (CONCERVE study). Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 40 (26), 3037–3046.
   PubMed Web of Science ®Google Scholar
• Lai, H.C., et al., 2014. PAX1/SOX1 DNA methylation and cervical neoplasia detection: a Taiwanese Gynecologic Oncology Group (TGOG) study. Cancer Medicine, 3 (4), 1062–1074.
   PubMed Web of Science ®Google Scholar
• Li, D., et al., 2012. Surgical-pathologic risk factors of pelvic lymph node metastasis in stage Ib1-IIb cervical cancer. Acta Obstetricia et Gynecologica Scandinavica, 91 (7), 802–809.
   PubMed Web of Science ®Google Scholar
• Lorincz, A.T., 2016. Virtues and weaknesses of DNA methylation as a test for cervical cancer prevention. Acta Cytologica, 60 (6), 501–512.
   PubMed Web of Science ®Google Scholar
• Lu, P., et al., 2022. Methylated septin 9 as a promising biomarker in the diagnosis and recurrence monitoring of colorectal cancer. Disease Markers, 2022, 7087885.
   PubMed Web of Science ®Google Scholar
• Macios, A. and Nowakowski, A., 2022. False negative results in cervical cancer screening-risks, reasons and implications for clinical practice and public health. Diagnostics, 12 (6), 1508.
   Web of Science ®Google Scholar
• Marcus, J., et al., 2019. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene, 38 (30), 5839–5859.
   PubMed Web of Science ®Google Scholar
• Noguchi, H., et al., 1987. Pelvic lymph node metastasis of uterine cervical cancer. Gynecologic Oncology, 27 (2), 150–158.
   PubMed Web of Science ®Google Scholar
• Powrozek, T., et al., 2014. Septin 9 promoter region methylation in free circulating DNA-potential role in noninvasive diagnosis of lung cancer: preliminary report. Medical Oncology (Northwood, London, England), 31 (4), 917.
   PubMed Web of Science ®Google Scholar
• Reinhardt, M.J., et al., 2001. Metastatic lymph nodes in patients with cervical cancer: detection with MR imaging and FDG PET. Radiology, 218 (3), 776–782.
   PubMed Web of Science ®Google Scholar
• Sahasrabuddhe, V.V., Luhn, P. and Wentzensen, N., 2011. Human papillomavirus and cervical cancer: biomarkers for improved prevention efforts. Future Microbiology, 6 (9), 1083–1098.
   PubMed Web of Science ®Google Scholar
• Schröck, A., et al., 2017. Free-circulating methylated DNA in blood for diagnosis, staging, prognosis, and monitoring of head and neck squamous cell carcinoma patients: an observational prospective cohort study. Clinical Chemistry, 63 (7), 1288–1296.
   PubMed Web of Science ®Google Scholar
• Solomon, D., et al., 2002. The 2001 Bethesda System: terminology for reporting results of cervical cytology. JAMA, 287 (16), 2114–2119.
   PubMed Web of Science ®Google Scholar
• Sun, J., et al., 2019. The role of (m)SEPT9 in screening, diagnosis, and recurrence monitoring of colorectal cancer. BMC Cancer, 19 (1), 450.
   PubMedGoogle Scholar
• Takeshima, N., et al., 1998. The value of squamous cell carcinoma antigen as a predictor of nodal metastasis in cervical cancer. Gynecologic Oncology, 68 (3), 263–266.
   PubMed Web of Science ®Google Scholar
• Thaker, N.G., et al., 2015. Survival outcomes for patients with stage IVB vulvar cancer with grossly positive pelvic lymph nodes: time to reconsider the FIGO staging system? Gynecologic Oncology, 136 (2), 269–273.
   PubMed Web of Science ®Google Scholar
• Wang, K.H., et al., 2015. Global methylation silencing of clustered proto-cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV. Cancer Medicine, 4 (1), 43–55.
   PubMed Web of Science ®Google Scholar
• Xu, F., et al., 2018. Preoperative SCC-Ag and thrombocytosis as predictive markers for pelvic lymphatic metastasis of squamous cervical cancer in early FIGO stage. Journal of Cancer, 9 (9), 1660–1666.
   PubMed Web of Science ®Google Scholar
• Xu, J., et al., 2021. A combination of methylation and protein markers is capable of detecting gastric cancer detection by combined markers. Epigenomics, 13 (19), 1557–1570.
   PubMed Web of Science ®Google Scholar
• Zhang, J., et al., 2017. Aberrant methylation of MEG3 functions as a potential plasma-based biomarker for cervical cancer. Scientific Reports, 7 (1), 6271.
   PubMedGoogle Scholar