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Journal of Obstetrics and Gynaecology Volume 19, 1999 - Issue 3
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Research Article

Pregnant women of 35 years of age or more: maternal serum markers or amniocentesis?

A. Antsaklis, N. Papantoniou, S. M Esogitis, S. Michalas, D. Aravantinos Maternal Fetal Medicine Unit, `Alexandra’ State and University Maternity Hospital, Athens, Greece
Pages 253-256 | Published online: 02 Jul 2009

  • Bogart M. H., Pandian M. R. and Jones O. W. (1987) Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities. Prenatal Diagnosis, 7, 623-630.
  • Canick J. A., Knight G. J., Palomaki G. E., Haddow J. E., Cuckle H. S. and Wald N. L. (1988) Low second trimester maternal serum unconjugated oestriol in pregnancies with Down's syndrome. British Journal of Obstetrics and Gynaecology, 95, 330-333.
  • Cheng E. Y., Luthy D. A., Zebelman A. M., Williams M. A., Lieppman R. E. and Hickok D. E. (1993) A prospective evaluation of a second-trimester screening test for fetal Down syndrome using maternal serum alpha-fetoprotein, hCG, and unconjugated estriol. Obstetrics and Gynecology, 81, 72-77.
  • Golbus M. S., Loughman W. D., Epstein C. J., Halbasch G., Stephens J. D. and Hall B. D. (1979) Prenatal genetic diagnosis in 3000 amniocentesis. New England Journal of Medicine, 300, 157-163.
  • Goodwin B. A. and Huether C. A. (1987) Revised estimates and projections of the Down syndrome births in the United States, and the effects of prenatal diagnosis utilization 1990-2002 Prenatal Diagnosis, 7, 261-271.
  • Haddow J. E., Palomaki G. E., Knight G. J., Williams J., Pulkkinen A., Canick J. A., Saller D. N. and Bowers G. B. (1992) Prenatal screening for Down's syndrome with use of maternal serum markers. New England Journal of Medicine, 327, 588-593.
  • Haddow J. E., Palomaki G. E., Knight G. J., Cunningham G. C., Lustig L. S. and Boyd P. A. (1994) Reducing the need for amniocentesis in women 35 years of age or older with serum markers for screening. New England Journal of Medicine, 330, 1114-1118.
  • Hook E. B., Cross P. K. and Schreinemachers D. M. (1983) Chromosomal abnormality rates at amniocentesis and in live-born infants. J.A.M.A., 249, 2034-2038.
  • Merkatz I. R., Nitowsky H. M., Macri J. N. and Johnson W. E. (1984) An association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities. American Journal of Obstetrics and Gynecology, 148, 886-894.
  • National Institute of Child Development National Registry for Amniocentesis Study Group (1976) Midtrimester amniocentesis for prenatal diagnosis; safety and accuracy. J.A.M.A., 236, 1471-1476.
  • Petrocik E., Wassman E. R. and Kelly J. C. (1989) Prenatal screening for Down syndrome with maternal serum human chorionic gonadotropin levels. American Journal of Obstetrics and Gynecology, 161, 1168-1173.
  • Phillips O. P., Elias S., Shulman L. P., Andersen R. N., Morgan C. D. and Simpson J. L. (1992) Maternal serum screening for fetal Down syndrome in women less than 35 years of age using alpha-fetoprotein, hCG, and unconjugated estrio: a prospective 2-year study. Obstetrics and Gynecology, 80, 353-358.
  • Smidt-Jensen S., Permin M., Philip J., Lundsteen C., Zachary J. M., Fowler S. E. and Gruning K. (1992) Randomised comparison of amniocentesis and transabdominal and transcervical chorionic villus sampling. Lancet, 340, 12371244.
  • Tabor A., Philip J., Madsen M., Bang J., Obel E. B. and Norgaard-Pedersen B. (1986) Randomized controlled trial of genetic amniocentesiss in 4606 low-risk women. Lancet, 1287-1293.
  • Wald N. J., Cuckle H. S., Densem J. W., Nanchahal K., Royston P., Chard T, Haddow J. E., Knight G. J., Palomaki G. E. and Canick J. A. (1988) Maternal serum screening for Down's syndrome in early pregnancy. British Medical Journal, 297, 883-887.
  • Wald N. J., Kennard A., Densem J. W., Cuckle H. S., Chard T and Butler L. (1992) Antenatal maternal serum screening for Down's syndrome: results of a demonstration project. British Medical Journal, 305, 391-394.
  • Working Party on Amniocentesis (1991) An assessment of the hazards of amniocentesis. British Journal of Obstetrics and Gynaecology, 98, 866-870.

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