42
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Reduction by Dietary Matrix Metalloproteinase Inhibitor BAY 12-9566N of Neoplastic Development Induced by Diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in Rats

, , , &
Pages 305-316 | Published online: 09 Oct 2008

REFERENCES

  • Beckett R. P., Davidson A. H., Drummond A. H., Huxley P., Whittaker M. Recent advances in matrix metalloproteinase inhibitor research. Drug Disc. Ther. 1996; 1: 16–26
  • Brown P. D. Matrix metalloproteinase inhibitors: a novel class of anticancer agents. Adv. Enzyme Regul. 1995; 35: 293–301
  • Egeblad M., Web A. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2002; 2: 161–174
  • Erlichman C., Adjei A. A., Alberts S. R., Sloan J. A., Goldberg R. M., Pitot H. C., Rubin J., Atherton P. J., Klee G. G., Humphrey R. Phase I study of the matrix metalloproteinase inhibitor, BAY 12–9566. Ann. Oncol. 2001; 12: 389–395
  • Gabriel K. R. A simple method of multiple comparisons of means. J. Am. Stat. Assoc. 1978; 73: 724–729
  • Genter M. B., Burman D. M., Vijayakumar S., Ebert C. L., Aronow B. J. Genomic analysis of alachlor-induced oncogenesis in rat olfactory mucosa. Physiol. Genom. 2002; 12: 35–45
  • Genter M. B., Warner B. M., Krell H. W., Bolon B. Reduction of Alachlor-induced olfactory mucosal neoplasms by the matrix metalloproteinase inhibitor RO28-2653. Toxicol. Pathol. 2005; 33: 593–539
  • Gomez D. E., Alonso D. F., Yoshiji H., Thorgierrson U. P. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell Biol. 1997; 74: 111–122
  • Goss K. J., Brown P. D., Matrisian L. M. Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis. Intl. J. Cancer. 1998; 78: 629–635
  • Grams F., Branstetter H., D'Alo S., Geppert D., Krell H. W., Leinert H., Livi V., Menta E., Oliva A., Zimmerman G. Pyrimidine-2,4-6-triones: a new effective and selective class of matrix metalloproteinase inhibitors. Biol. Chem. 2001; 382: 1277–1285
  • Hirte H., Goel P., Seymour L., Huan S., Stewart D., Yau J., Arnold A., Holohan S., Waterfield B., Bates S., Bennett K., Walsh W., Elias I. A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours. Ann. Oncol. 2000; 11: 1579–1584
  • Iatropoulos M. J. Accelerated rodent bioassy predictive of chemical carcinogenesis. Exp. Toxicol. Pathol. 1992; 44: 481–487
  • Iatropoulos M. J., Williams G. M., Wang C. X., Brunnemann K. D., Leber A. P. Assessment of chronic toxicity and carcinogenicity in rats of Wingstay®100, a rubber antioxidant/antizonant. Exp. Toxicol. Pathol. 1997; 49: 153–165
  • Iatropoulos M. J., Jeffrey A. M., Enzmann H. G., von Keutz E., Schlueter G., Williams G. M. Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassy in rats of moxifloxacin, a quinololone antibiotic. Exp. Toxicol. Pathol. 2001; 53: 345–357
  • Iatropoulos M. J., Wang C. X., von Keutz E., Williams G. M. Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug. Exp. Toxicol. Pathol. 2006; 57: 252–259
  • Levy D. E., Ezrin A. M. Matrix metalloproteinase inhibiting drugs. Emerg. Drugs 1997; 2: 205–230
  • Liotta L., Stetler-Stevenson W. Metalloproteinases and cancer invasion. Semin. Cancer Biol. 1990; 1: 99–106
  • Lynch C. C., Matrisian L. M. Matrix metalloproteinases in tumor-host communication. Differentiation 2002; 70: 561–573
  • Mäkelä M., Larjava H., Pirilä E., Maisi P., Salo T., Sorsa T., Vitto V-J. Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes. Exp. Cell Res. 1999; 251: 67–78
  • Maquoi E., Sounni N. E., Devy L, Olivier F., Frankenne F., Krell H. W., Grams F., Foidart J. N., Noel A. Anti invasive, antitumoral, and antianiogenic efficacy of a pyrimidine-2-4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor. Clin. Cancer Res. 2004; 10: 4038–4047
  • Ogata T., Teshima T., Kagawa K., Hishikawa Y., Takahashi Y., Kawaguchi A., Suzumoto Y., Nojima K., Furusawa Y., Matsuura N. Particle irradiation suppresses metastatic potential of cancer cells. Cancer Res. 2005; 65(1)113–120
  • Peto R., Pike M. C., Day N. E., Gray R. G., Lee P. N., Parish S., Peto, Wahrendorf J. Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal, R. Montesano, H. Bartsch, L. Tomatis. IARC, LyonFrance 1980; 311–426, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Suppl. 2.
  • Shepherd F. A., Giaccone G., Seymour L., Debruyne C., Bezjak A., Hirsch V., Smylie M., Rubin S., Martins H., Lamont A., Krzakowski J., Sadura A., Zee B. Prospective, randomized, double-blind placebo controlled trial of Marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: A trial of the National Cancer Institute of Canada—Clinical Trials group and the European Organization for Research and Treatment of Cancer. J. Clin. Oncol. 2002; 20(22)4434–4439
  • Stamenkovic I. Matrix metalloproteinase in tumor invasion and metastasis. Semin. Cancer Biol. 2002; 10: 415–433
  • Stamenkovic I. Extracellular matrix remodeling: the role of matrix metalloproteinases. J. Pathol. 2003; 200: 448–464
  • Sternlicht J. D., Werb Z. Matrix metalloproteinases. Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins, T. Kreis, R. Vale. Oxford University Press, New York 1999; 503–603
  • Sternlicht M. D., Werb Z. How matrix metalloproteinases regulate cell behavior. Ann. Rev. Cell Dev. Biol. 2001; 17: 463–516
  • Stetler-Stevenson W. G., Yu A. E. Proteases in invasion: matrix metalloproteinases. Semin. Cancer Biol. 2001; 11: 143–152
  • Williams G. M., Iatropoulos M. J. Principles of testing for carcinogenic activity. Principles and Methods of Toxicology, W. Hayes, Philadelphia, Pennsylvania, USA 2001; 959–1000
  • Williams G. M., Iatropoulos M. J., Weisburger J. H. Chemical carcinogen mechanisms of action and implications for testing methodology. Exp. Toxicol. Pathol. 1996; 48: 101–111
  • Wyatt C. A., Geoghegan J. C., Brinckerhoff C. E. Short hairpin RNA-mediated inhibition of matrix metalloproteinase-1 in MDA-231 Cells: effects on matrix destruction and tumor growth. Cancer Res. 2005; 65(23)11101–11108
  • Xu X., Wang Y., Chen Z., Sternlicht J. D., Hidalgo M., Steffensen B. Matrix metalloproteinase-2 contributes to cancer cell migration on collagen. Cancer Res. 2005; 65(1)130–137
  • Zhou Y., Yu C., Miao X., Tan W., Liang G., Xiong P., Sun T., Lix D. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis 2004; 25(3)399–404

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.