Effect of aged garlic extract on wound healing: A new frontier in wound management

References

• Balasenthil, S., Arivazhagan, S., Nagini, S. (2000). Garlic enhances circulatory antioxidants during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. J Ethnopharmacol 72:429–433.
   PubMed Web of Science ®Google Scholar
• Barth, D., Musiol, H.J., Schutt, M., Fiori, S., Milbradt, A.G., Renner, C., Moroder, L. (2003). The role of cystine knots in collagen folding and stability, part I. Conformational properties of (Pro-Hyp-Gly)5 and (Pro-(4S)-FPro-Gly)5 model trimers with an artificial cystine knot. Chemistry 9:3692–3702.
   PubMed Web of Science ®Google Scholar
• Baruchin, A.M., Sagi, A., Yoffe, B., Ronen, M. (2001). Garlic burns. Burns 27:781–782.
   PubMed Web of Science ®Google Scholar
• Bates, D.O., Jones, R.O. (2003). The role of vascular endothelial growth factor in wound healing. Int J Low Extrem Wounds 2:107–120.
   PubMedGoogle Scholar
• Bernstein, E.F., Chen, Y.Q., Tamai, K., Shepley, K.J., Resnik, K.S., Zhang, H., Tuan, R., Mauviel, A., Uitto, J. (1994). Enhanced elastin and fibrillin gene expression in chronically photodamaged skin. J Invest Dermatol 103:182–186.
   PubMed Web of Science ®Google Scholar
• Berry, D.P., Harding, K.G., Stanton, M.R., Jasani, B., Ehrlich, H.P. (1998). Human wound contraction: collagen organization, fibroblasts, and myofibroblasts. Plast Reconstr Surg 102:124–131.
   PubMed Web of Science ®Google Scholar
• Burnham, B.E. (1995). Garlic as a possible risk for postoperative bleeding. Plast Reconstr Surg 95:213.
   PubMed Web of Science ®Google Scholar
• Choi, S.Y., Chung, M.J., Seo, W.D., Shin, J.H., Shon, M.Y., Sung, N.J. (2006). Inhibitory effects of Orostachys japonicus extracts on the formation of N-nitrosodimethylamine. J Agric Food Chem 54:6075–6078.
   PubMed Web of Science ®Google Scholar
• Clark, R.A., Lin, F., Greiling, D., An, J., Couchman, J.R. (2004). Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan. J Invest Dermatol 122:266–277.
   PubMed Web of Science ®Google Scholar
• Dahlberg, L., Billinghurst, R.C., Manner, P., Nelson, F., Webb, G., Ionescu, M., et al. (2000). Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1). Arthritis Rheum 43:673–682.
   PubMed Web of Science ®Google Scholar
• Dai, Q., Huang, J., Klitzman, B., Dong, C., Goldschmidt-Clermont, P.J., March, K.L., et al. (2004). Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. Circulation 110:2467–2475.
   PubMed Web of Science ®Google Scholar
• DiPietro, L.A. (1995). Wound healing: the role of the macrophage and other immune cells. Shock 4:233–240.
   PubMed Web of Science ®Google Scholar
• Ehrlich, H.P., Rajaratnam, J.B. (1990). Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction. Tissue Cell 22:407–417.
   PubMed Web of Science ®Google Scholar
• Ejaz, E., Shimada, A., Woong, L.C. (2005). Toxicological screening for the effects of short-term exposure of sidestream cigarette smoke on angiogenesis. Drug Chem Toxicol 28:447–465.
   PubMed Web of Science ®Google Scholar
• Ejaz, S., Akram, W., Lim, C.W., Lee, J.J., Hussain, I. (2004). Endocrine disrupting pesticides: a leading cause of cancer among rural people in Pakistan. Exp Oncol 26:98–105.
   PubMed Web of Science ®Google Scholar
• Ejaz, S., Chekarova, I., Ashraf, M., Lim, C.W. (2006). A novel 3-D model of chick chorioallantoic membrane for ameliorated studies in angiogenesis. Cancer Invest 24:567–575.
   PubMed Web of Science ®Google Scholar
• Feugate, J.E., Li, Q., Wong, L., Martins-Green, M. (2002a). The CXC chemokine, cCAF, stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. J Cell Biol 156:161–172.
   PubMed Web of Science ®Google Scholar
• Feugate, J.E., Wong, L., Li, Q.J., Martins-Green, M. (2002b). The CXC chemokine, cCAF, stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. BMC Cell Biol 3:13.
   PubMedGoogle Scholar
• Folkman, J. (2003). Angiogenesis and proteins of the hemostatic system. J Thromb Haemost 1:1681–1682.
   PubMed Web of Science ®Google Scholar
• Folkman, J. (2006). Angiogenesis. Annu Rev Med 57:1–18.
   PubMed Web of Science ®Google Scholar
• Folkman, J. (2007). Is angiogenesis an organizing principle in biology and medicine? J Pediatr Surg 42:1–11.
   PubMed Web of Science ®Google Scholar
• Gallin, W.J., Hepperle, B. (1998). Burn healing in organ cultures of embryonic chicken skin: a model system. Burns 24:613–620.
   PubMed Web of Science ®Google Scholar
• Garty, B.Z. (1993). Garlic burns. Pediatrics 91:658–659.
   PubMed Web of Science ®Google Scholar
• Goodman, V.L., Brewer, G.J., Merajver, S.D. (2004). Copper deficiency as an anticancer strategy. Endocr Relat Cancer 11:255–263.
   PubMed Web of Science ®Google Scholar
• Gosain, A., DiPietro, L.A. (2004) Aging and wound healing. World J.Surg 28:321–326.
   PubMed Web of Science ®Google Scholar
• Grudzinski, I.P., Frankiewicz-Jozko, A., Bany, J. (2001). Diallyl sulfide—a flavour component from garlic (Allium sativum) attenuates lipid peroxidation in mice infected with Trichinella spiralis. Phytomedicine 8:174–177.
   PubMed Web of Science ®Google Scholar
• Hansen, G.L., Sparrow, E.M., Kokate, J.Y., Leland, K.J., Iaizzo, P.A. (1997). Wound status evaluation using color image processing. IEEE Trans.Med.Imaging 16:78–86.
   PubMed Web of Science ®Google Scholar
• Harsum, S., Clarke, J.D., Martin, P. (2001). A reciprocal relationship between cutaneous nerves and repairing skin wounds in the developing chick embryo. Dev Biol 238:27–39.
   PubMed Web of Science ®Google Scholar
• Ho, S.E., Ide, N., Lau, B.H. (2001). S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process. Phytomedicine 8:39–46.
   PubMed Web of Science ®Google Scholar
• Horie, T., Awazu, S., Itakura, Y., Fuwa, T. (1992). Identified diallyl polysulfides from an aged garlic extract which protects the membranes from lipid peroxidation. Planta Med 58:468–469.
   PubMed Web of Science ®Google Scholar
• Ide, N., Lau, B.H. (1997). Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. J Pharm Pharmacol 49:908–911.
   PubMed Web of Science ®Google Scholar
• Ide, N., Lau, B.H. (1999a). Aged garlic extract attenuates intracellular oxidative stress. Phytomedicine 6:125–131.
   PubMed Web of Science ®Google Scholar
• Ide, N., Lau, B.H. (1999b). S-allylcysteine attenuates oxidative stress in endothelial cells. Drug Dev Ind Pharm 25:619–624.
   PubMed Web of Science ®Google Scholar
• Ide, N., Lau, B.H. (2001). Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kappa b activation. J Nutr 131:1020S–1026S.
   PubMed Web of Science ®Google Scholar
• Jacobi, J., Sydow, K., von Degenfeld, G, Zhang, Y., Dayoub, H., Wang, B., et al. (2005). Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation 111:1431–1438.
   PubMed Web of Science ®Google Scholar
• James, J. (1999). Skin grafting in difficult situations. Trop Doct 29:41–42.
   PubMed Web of Science ®Google Scholar
• Kabasakal, L., Sehirli, O., Cetinel, S., Cikler, E., Gedik, N., Sener, G. (2005). Protective effect of aqueous garlic extract against renal ischemia/reperfusion injury in rats. J Med Food 8:319–326.
   PubMed Web of Science ®Google Scholar
• Kakko, J., Heilig, M., Sarman, I. (2008). Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series. Drug Alcohol Depend 96:69–78.
   PubMed Web of Science ®Google Scholar
• Kasuga, S., Uda, N., Kyo, E., Ushijima, M., Morihara, N., Itakura, Y. (2001). Pharmacologic activities of aged garlic extract in comparison with other garlic preparations. J Nutr 131:1080S–1084S.
   PubMed Web of Science ®Google Scholar
• Kourounakis, P.N., Rekka, E.A. (1991). Effect on active oxygen species of alliin and Allium sativum (garlic) powder. Res Commun Chem Pathol Pharmacol 74:249–252.
   PubMedGoogle Scholar
• Kovacs, E.J., DiPietro, L.A. (1994). Fibrogenic cytokines and connective tissue production. FASEB J 8:854–861.
   PubMed Web of Science ®Google Scholar
• Kubo, S., Inui, T., Hasegawa, H., Yoshimine, T. (2005). Repair of intractable cerebrospinal fluid rhinorrhea with mucosal flaps and recombinant human basic fibroblast growth factor: technical case report. Neurosurgery 56:E627.
   PubMed Web of Science ®Google Scholar
• Kyo, E., Uda, N., Ushijima, M., Kasuga, S., Itakura, Y. (1999). Prevention of psychological stress-induced immune suppression by aged garlic extract. Phytomedicine 6:325–330.
   PubMed Web of Science ®Google Scholar
• Lachter, J., Babich, J.P., Brookman, J.C., Factor, A.Y. (2003). Garlic: a way out of work. Mil Med 168:499–500.
   PubMed Web of Science ®Google Scholar
• Li, J., Zhang, Y.P., Kirsner, R.S. (2003). Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix. Microsc Res Tech 60:107–114.
   PubMed Web of Science ®Google Scholar
• Li, V.W., Li, W.W. (2008). Antiangiogenesis in the treatment of skin cancer. J Drugs Dermatol 7:s17–s24.
   PubMed Web of Science ®Google Scholar
• Magers, T., Talbot, P., DiCarlantonio, G., Knoll, M., Demers, D., Tsai, I., et al. (1995). Cigarette smoke inhalation affects the reproductive system of female hamsters. Reprod Toxicol 9:513–525.
   PubMed Web of Science ®Google Scholar
• Martins-Green, M. (2001). The chicken chemotactic and angiogenic factor (cCAF), a CXC chemokine. Int J Biochem Cell Biol 33:427–432.
   PubMed Web of Science ®Google Scholar
• Martins-Green, M., Feugate, J.E. (1998). The 9E3/CEF4 gene product is a chemotactic and angiogenic factor that can initiate the wound-healing cascade in vivo. Cytokine 10:522–535.
   PubMed Web of Science ®Google Scholar
• Mattick, R.P., Kimber, J., Breen, C., Davoli, M. (2008) Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev CD002207.
   PubMed Web of Science ®Google Scholar
• May, J.M., Qu, Z.C. (2005). Transport and intracellular accumulation of vitamin C in endothelial cells: relevance to collagen synthesis. Arch Biochem Biophys 434:178–186.
   PubMed Web of Science ®Google Scholar
• Miyashita, H., Kanemura, M., Yamazaki, T., Abe, M., Sato, Y. (2004). Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene. Arterioscler Thromb Vasc Biol 24:878–884.
   PubMed Web of Science ®Google Scholar
• Mohammad, F.K., al Badrany, M.S., al Hasan, A.M. (1993). Detomidine-ketamine anaesthesia in chickens. Vet Rec 133:192.
   PubMed Web of Science ®Google Scholar
• Molina, P.E., McClain, C., Valla, D., Guidot, D., Diehl, A.M., Lang, C.H., et al. (2002). Molecular pathology and clinical aspects of alcohol-induced tissue injury. Alcohol Clin Exp Res 26:120–128.
   PubMed Web of Science ®Google Scholar
• Nasulewicz, A., Opolski, A. (2002). [The role of copper in tumor angiogenesis—clinical implications]. Postepy Hig Med Dosw 56:691–705.
   PubMedGoogle Scholar
• Nelson, F., Dahlberg, L., Laverty, S., Reiner, A., Pidoux, I., Ionescu, M., et al. (1998). Evidence for altered synthesis of type II collagen in patients with osteoarthritis. J Clin Invest 102:2115–2125.
   PubMed Web of Science ®Google Scholar
• Nissen, N.N., Polverini, P.J., Gamelli, R.L., DiPietro, L.A. (1996). Basic fibroblast growth factor mediates angiogenic activity in early surgical wounds. Surgery 119:457–465.
   PubMed Web of Science ®Google Scholar
• Nissen, N.N., Polverini, P.J., Koch, A.E., Volin, M.V., Gamelli, R.L., DiPietro, L.A. (1998). Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 152:1445–1452.
   PubMed Web of Science ®Google Scholar
• Norfleet, A.M., Huang, Y., Sower, L.E., Redin, W.R., Fritz, R.R., Carney, D.H. (2000). Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia. Wound Repair Regen 8:517–529.
   PubMed Web of Science ®Google Scholar
• Ottl, J., Battistuta, R., Pieper, M., Tschesche, H., Bode, W., Kuhn, K., et al. (1996). Design and synthesis of heterotrimeric collagen peptides with a built-in cystine-knot. Models for collagen catabolism by matrix-metalloproteases. FEBS Lett 398:31–36.
   PubMed Web of Science ®Google Scholar
• Ozaki, W., Buchman, S.R. (1998). Use of scanning electron microscopy in the evaluation of craniosynostosis. J Craniofac Surg 9:30–38.
   PubMed Web of Science ®Google Scholar
• Ozturk, C., Nissannov, J., Dubin, S., Shi, W.Y., Nichols, J., Mark, R. (1995). Measurement of wound healing by image analysis. Biomed Sci Instrum 31:189–193.
   PubMedGoogle Scholar
• Pentcheff, N.D., Bolender, R.P. (1992). Computer-assisted data collection for stereology: rationale and description of point counting stereology (PCS) software. Microsc Res Tech 21:347–354.
   PubMed Web of Science ®Google Scholar
• Pirnay, S., Megarbane, B., Decleves, X., Risede, P., Borron, S.W., Bouchonnet, S., et al. (2008). Buprenorphine alters desmethylflunitrazepam disposition and flunitrazepam toxicity in rats. Toxicol Sci 106:64–73.
   PubMed Web of Science ®Google Scholar
• Power, C., Wang, J.H., Sookhai, S., Street, J.T., Redmond, H.P. (2001). Bacterial wall products induce downregulation of vascular endothelial growth factor receptors on endothelial cells via a CD14-dependent mechanism: implications for surgical wound healing. J Surg Res 101:138–145.
   PubMed Web of Science ®Google Scholar
• Raath, J.P., Quandt, S.K., Malan, J.H. (1992). Ostrich (Struthio camelus) immobilisation using carfentanil and xylazine and reversal with yohimbine and naltrexone. J S Afr Vet Assoc 63:138–140.
   PubMed Web of Science ®Google Scholar
• Rees, M., Hague, S., Oehler, M.K., Bicknell, R. (1999). Regulation of endometrial angiogenesis. Climacteric 2:52–58.
   PubMedGoogle Scholar
• Rosen, R.T., Hiserodt, R.D., Fukuda, E.K., Ruiz, R.J., Zhou, Z., Lech, J., et al. (2001). Determination of allicin, S-allylcysteine, and volatile metabolites of garlic in breath, plasma, or simulated gastric fluids. J Nutr 131:968S–971S.
   PubMed Web of Science ®Google Scholar
• Roux, P., Villes, V., Blanche, J., Bry, D., Spire, B., Feroni, I., et al. (2008). Buprenorphine in primary care: risk factors for treatment injection and implications for clinical management. Drug Alcohol Depend 97:105–113.
   PubMed Web of Science ®Google Scholar
• Ryu, K., Ide, N., Matsuura, H., Itakura, Y. (2001). N alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract. J Nutr 131:972S–976S.
   PubMed Web of Science ®Google Scholar
• Sanders, J.E., Goldstein, B.S., Leotta, D.F., Richards, K.A. (1999). Image processing techniques for quantitative analysis of skin structures. Comput.Meth Progr Biomed 59:167–180.
   PubMed Web of Science ®Google Scholar
• Sengel, P. (1955). [Effect of tyrosine on pigmentation of feather germ of embryonic chick skin cultured in vitro.]. C RSeances SocBiol Fil 149:1479–1482.
   PubMedGoogle Scholar
• Senturk, N., Keles, G.C., Kaymaz, F.F., Yildiz, L., Acikgoz, G., Turanli, A.Y. (2004). The role of ascorbic acid on collagen structure and levels of serum interleukin-6 and tumour necrosis factor-alpha in experimental lathyrism. Clin Exp Dermatol 29:168–175.
   PubMed Web of Science ®Google Scholar
• Shin, I.S., Rodgers, W.J., Gomaa, E.A., Strasburg, G.M., Gray, J.I. (2002). Inhibition of heterocyclic aromatic amine formation in fried ground beef patties by garlic and selected garlic-related sulfur compounds. J Food Prot 65:1766–1770.
   PubMed Web of Science ®Google Scholar
• Squires, G.R., Okouneff, S., Ionescu, M., Poole, A.R. (2003). The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis. Arthritis Rheum 48:1261–1270.
   PubMed Web of Science ®Google Scholar
• Swift, M.E., Kleinman, H.K., DiPietro, L.A. (1999). Impaired wound repair and delayed angiogenesis in aged mice. Lab Invest 79:1479–1487.
   PubMed Web of Science ®Google Scholar
• Szende, B., Tyihak, E., Trezl, L. (2001). Role of arginine and its methylated derivatives in cancer biology and treatment. Cancer Cell Int 1:3.
   PubMedGoogle Scholar
• Tonnesen, M.G., Feng, X., Clark, R.A. (2000). Angiogenesis in wound healing. J Invest Dermatol Symp Proc 5:40–46.
   PubMed Web of Science ®Google Scholar
• Winstock, A.R. (2008). Buprenorphine use by the smoking route in gaols in NSW. Drug Alcohol Rev 27:449–450.
   PubMed Web of Science ®Google Scholar
• Wu, C.C., Sheen, L.Y., Chen, H.W., Tsai, S.J., Lii, C.K. (2001). Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells. Food Chem Toxicol 39:563–569.
   PubMed Web of Science ®Google Scholar
• Yamaguchi, Y., Yoshikawa, K. (2001). Cutaneous wound healing: an update. J Dermatol 28:521–534.
   PubMed Web of Science ®Google Scholar
• Yamasaki, T., Lau, B.H. (1997). [Garlic compounds protect vascular endothelial cells from oxidant injury]. Nippon Yakurigaku Zasshi 110(Suppl 1):138P–141P.
   PubMedGoogle Scholar
• Zeilinger, K., Sauer, I.M., Pless, G., Strobel, C., Rudzitis, J., Wang, A., et al. (2002). Three-dimensional coculture of primary human liver cells in bioreactors for in vitro drug studies: effects of the initial cell quality on the long-term maintenance of hepatocyte-specific functions. Altern Lab Anim 30:525–538.
   PubMed Web of Science ®Google Scholar