Cytotoxicity, mutagenicity, and antimutagenicity of the gentisic acid on HTC cells

References

• Acevedo, H.R., et al., 2006. Effect of 6-nonadecyl salicylic acid and its methyl ester on the induction of micronuclei in polychromatic erythrocytes in mouse peripheral blood. Mutation Research, 609, 43–46.
   PubMed Web of Science ®Google Scholar
• Almeida, I.V., Cavalcante, F.M.L., and Vicentini, V.E.P., 2016. Different responses of vanillic acid, a phenolic compound, in HTC cells: cytotoxicity, antiproliferative activity, and protection from DNA-induced damage. Genetics and Molecular Research, 15, 1–12.
   Web of Science ®Google Scholar
• Ashidate, K., et al., 2005. Gentisic acid, an aspirin metabolite, inhibits oxidation of low-density lipoprotein and the formation of cholesterol ester hydroperoxides in human plasma. European Journal of Pharmacology, 513, 173–179.
   PubMed Web of Science ®Google Scholar
• Belles, J.M., et al., 1999. Gentisic acid as a pathogen-inducible signal, additional to salicylic acid for activation of plant defenses in tomato. Molecular Plant-Microbe Interactions, 12, 227–235.
   Web of Science ®Google Scholar
• Bochner, F., et al., 1981. Salicylate metabolite kinetics after several salicylates. Clinical Pharmacology & Therapeutics, 30, 266–275.
   PubMed Web of Science ®Google Scholar
• Broinizi, P.R.B., et al., 2007. Avaliação da atividade antioxidante dos compostos fenólicos naturalmente presentes em subprodutos do pseudofruto de caju (Anacardium occidentale L.). Ciência e Tecnologia de Alimentos, 27 (4), 902–908.
   Google Scholar
• Carbonneau, M.A., et al., 1997. Supplementation with wine phenolic compounds increases the antioxidant capacity of plasma and vitamin E of low-density lipoprotein without changing the lipoprotein Cu2+ oxidizability: possible explanation by phenolic location. European Journal of Clinical Nutrition, 51 (10), 682–690.
   PubMed Web of Science ®Google Scholar
• Exner, M., et al., 2000. The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein. FEBS Letters, 470, 47–50.
   PubMed Web of Science ®Google Scholar
• Giri, A.K., Adhikari, N., and Khan, K.A., 1996. Comparative genotoxicity of six salicylic acid derivatives in bone marrow cells of mice. Mutation Research, 370, 1–9.
   PubMed Web of Science ®Google Scholar
• Godoy-Caballero, M.P., Acedo-Valenzuela, M.I., and Galeano-Diaz, T., 2012. Simple quantification of phenolic compounds present in the minor fraction of virgin olive oil by LC-DAD-FLD. Talanta, 101, 479–487.
   PubMed Web of Science ®Google Scholar
• Gomes-Rochette, N.F., et al., 2016. Fruit as potent natural antioxidants and their biological effects. Current Pharmaceutical Biotechnology, 17, 986–993.
   PubMed Web of Science ®Google Scholar
• Harris, C.S., et al., 2007. Plant phenolics regulate neoplastic cell growth and survival: a quantitative structure–activity and biochemical analysis. Canadian Journal of Physiology and Pharmacology, 85, 1124–1138.
   PubMed Web of Science ®Google Scholar
• Hermann, M., et al., 1999. Salicylate inhibits LDL oxidation initiated by superoxide/nitric oxide radicals. FEBS Letters, 445, 212–214.
   PubMed Web of Science ®Google Scholar
• Hutt, A.J., Caldwell, J., and Smith, R.T., 1986. The metabolism of aspirin in man: a population study. Xenobiotica, 16, 239–249.
   PubMed Web of Science ®Google Scholar
• Hyun-Jung, K., Hyang-Sook, C., and Yang, R., 2000. Inhibition of benzo[a]pyrene-induced cytotoxicity and cytochrome P4501A activity by dietary flavonoids in human liver cell model: structure–activity relationship. Biotechnology Letters, 22, 1941–1946.
   Web of Science ®Google Scholar
• Juurlink, B.H.J., et al., 2014. Hydroxybenzoic acid isomers and the cardiovascular system. Nutrition Journal, 13, 63–73.
   PubMed Web of Science ®Google Scholar
• Kada, T., Morita, K., and Inoue, T., 1978. Anti-mutagenic action of vegetable factor(s) on the mutagenic principle of tryptophan pyrolysate. Mutation Research, 53 (3), 351–353.
   PubMed Web of Science ®Google Scholar
• Krizková, L., et al., 2000. Phenolic acids inhibit chloroplast mutagenesis in Euglena gracilis. Mutation Research, 469, 107–114.
   PubMed Web of Science ®Google Scholar
• Li, H., et al., 2014. Antioxidant and anti-inflammatory activities of methanol extracts of Tremella fuciformis and its major phenolic acids. Journal of Food Science, 79, 460–468.
   PubMed Web of Science ®Google Scholar
• Liu, S., and Edwards, D.S., 2001. Stabilization of (90)y-labeled DOTA-Biomolecule conjugates using gentisic acid and ascorbic acid. Bioconjugation Chemistry, 12 (4), 554–558.
   PubMed Web of Science ®Google Scholar
• Mosmann, T., 1983. Rapid Colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods, 65, 55–56.
   PubMed Web of Science ®Google Scholar
• Nardini, M., et al., 1997. Effect of caffeic acid dietary supplementation on the antioxidant defense system in rat: an in vivo study. Archives of Biochemistry and Biophysic, 342 (1), 157–160.
   PubMed Web of Science ®Google Scholar
• Niikawa, M., Shin, S., and Nagase, H., 2007. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomedicine & Pharmacotherapy, 61, 113–119.
   PubMed Web of Science ®Google Scholar
• Salvadori, D.M.F., Ribeiro, L.R., and Fenech, M., 2003. Teste do micronúcleo em células humanas in vitro. In: L.R. Ribeiro, D.M.F. Salvadori, and E.K. Marques, eds. Mutagênese Ambiental. Canoas: Editora ULBRA, 201–224.
   Google Scholar
• Sharma, S., Khan, N., and Sultana, S., 2004a. Study on prevention of two-stage skin carcinogenesis by Hibiscus rosa sinensis extract and the role of its chemical constituent, gentisic acid, in the inhibition of tumor promotion response and oxidative stress in mice. European Journal of Cancer Prevention, 13, 53–63.
   PubMed Web of Science ®Google Scholar
• Sharma, S., Khan, N., and Sultana, S., 2004b. Modulatory effect of gentisic acid on the augmentation of biochemical events of tumor promotion stage by benzoyl peroxide and ultraviolet radiation in Swiss albino mice. Toxicology Letters, 153, 293–302.
   PubMed Web of Science ®Google Scholar
• Taner, G., et al., 2016. Use of in vitro assays to assess the potential cytotoxic, genotoxic and antigenotoxic effects of vanillic and cinnamic acid. Drug and Chemical Toxicology, 16, 1–8.
   Web of Science ®Google Scholar
• Visioli, F., and Galli, C., 1998. The effect of minor constituents of olive oil on cardiovascular disease: new findings. Nutrition Reviews, 56, 142–147.
   PubMed Web of Science ®Google Scholar
• Wang, L., and Sweet, D.H., 2012. Potential for food–drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8) and 4 (SLC22A11). Biochemical Pharmacology, 84, 1088–1095.
   PubMed Web of Science ®Google Scholar
• Zahin, M., Ahmad, I., and Aqil, F., 2016. Antioxidant and antimutagenic potential of Psidium guajava leaf extracts. Drug and Chemical Toxicology, 7, 1–8.
   Google Scholar