Protective effect of thymoquinone, the main component of Nigella Sativa, against diazinon cardio-toxicity in rats

References

• Abdel-Daim, M.M., et al., 2015. Synergistic ameliorative effects of sesame oil and alpha-lipoic acid against subacute diazinon toxicity in rats: hematological, biochemical, and antioxidant studies. Canadian Journal of Physiology and Pharmacology, 94 (1), 81–88.
   PubMed Web of Science ®Google Scholar
• Aboul-Ela, E.I., 2002. Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 516 (1), 11–17.
   PubMed Web of Science ®Google Scholar
• Al-Attar, A.M. and Al-Taisan, W., 2010. Preventive effects of black seed (Nigella sativa) extract on Sprague Dawley rats exposed to diazinon. Australian Journal of Basic and Applied Sciences, 4 (5), 957–968.
   Google Scholar
• Al-Attar, A.M., Elnaggar, M.H., and Almalki, E.A., 2016. Physiological study on the influence of some plant oils in rats exposed to a sublethal concentration of diazinon. Saudi Journal of Biological Sciences, 24 (6), 1162–1171.
   PubMed Web of Science ®Google Scholar
• Al-Haj, M., Nasser, A., and Anis, A., 2005. Survey of pesticides used in Qat cultivation in Dhale and Yafe and their adverse effects. Journal of Natural and Applied Science, 9, 103–110.
   Google Scholar
• Ali, B. and Blunden, G., 2003. Pharmacological and toxicological properties of Nigella sativa. Phytotherapy Research, 17 (4), 299–305.
   PubMed Web of Science ®Google Scholar
• Bachowski, S., et al., 1997. Role of oxidative stress in the mechanism of dieldrin’s hepatotoxicity. Annals of Clinical & Laboratory Science, 27 (3), 196–209.
   PubMed Web of Science ®Google Scholar
• Badary, O.A., et al., 1997. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Canadian Journal of Physiology and Pharmacology, 75 (12), 1356–1361.
   PubMed Web of Science ®Google Scholar
• Banerjee, B., et al., 1999. Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers. Toxicology Letters, 107 (1), 33–47.
   PubMed Web of Science ®Google Scholar
• Basarslan, F., et al., 2012. Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats. Human & Experimental Toxicology, 31 (7), 726–733.
   PubMed Web of Science ®Google Scholar
• Beydilli, H., et al., 2015. Evaluation of the protective effect of silibinin against diazinon induced hepatotoxicity and free-radical damage in rat liver. Iranian Red Crescent Medical Journal, 17 (4), e25310.
   PubMed Web of Science ®Google Scholar
• Bhatti, G., et al., 2014. Ameliorative role of melatonin against cypermethrin induced hepatotoxicity and impaired antioxidant defense system in Wistar rats. IOSR Journal of Environmental Science, Toxicology and Food Technology ( Technology), 8 (1), 39–48.
   Google Scholar
• Boroushaki, M.T., et al., 2013. Protective effect of pomegranate seed oil against acute toxicity of diazinon in rat kidney. Iranian Journal of Pharmaceutical Research: IJPR, 12 (4), 821.
   PubMed Web of Science ®Google Scholar
• Cakici, O. and Akat, E., 2013. Effects of oral exposure to diazinon on mice liver and kidney tissues: biometric analyses of histopathologic changes. Analytical and Quantitative Cytopathology and Histopathology, 35 (1), 7–16.
   PubMed Web of Science ®Google Scholar
• Danaei, G.H. and Karami, M., 2017. Protective effect of thymoquinone against diazinon-induced hematotoxicity, genotoxicity and immunotoxicity in rats. Environmental Toxicology and Pharmacology, 55, 217–222.
   PubMed Web of Science ®Google Scholar
• Darakhshan, S., et al., 2015. Thymoquinone and its therapeutic potentials. Pharmacological Research, 95, 138–158.
   PubMed Web of Science ®Google Scholar
• El-Demerdash, F.M. and Nasr, H.M., 2014. Antioxidant effect of selenium on lipid peroxidation, hyperlipidemia and biochemical parameters in rats exposed to diazinon. Journal of Trace Elements in Medicine and Biology, 28 (1), 89–93.
   PubMed Web of Science ®Google Scholar
• Ellman, G.L., et al., 1961. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7 (2), 88–90.
   PubMed Web of Science ®Google Scholar
• Flesar, J., et al., 2010. In vitro growth-inhibitory effect of plant-derived extracts and compounds against Paenibacillus larvae and their acute oral toxicity to adult honey bees. Veterinary Microbiology, 145 (1), 129–133.
   PubMed Web of Science ®Google Scholar
• Fortunato, J.J., et al., 2006. Lipid peroxidative damage on malathion exposure in rats. Neurotoxicity Research, 9 (1), 23–28.
   PubMed Web of Science ®Google Scholar
• Gali-Muhtasib, H., El-Najjar, N., and Schneider-Stock, R., 2006. The medicinal potential of black seed (Nigella sativa) and its components. Advances in Phytomedicine, 2, 133–153.
   Google Scholar
• Goreja, W., 2003. Black seed: nature’s miracle remedy. New York: Karger Publishers.
   Google Scholar
• Gultekin, F., Ozturk, M., and Akdogan, M., 2000. The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Archives of Toxicology, 74 (9), 533–538.
   PubMed Web of Science ®Google Scholar
• Hariri, A.T., et al., 2010. Sub-acute effects of diazinon on biochemical indices and specific biomarkers in rats: protective effects of crocin and safranal. Food and Chemical Toxicology, 48 (10), 2803–2808.
   PubMed Web of Science ®Google Scholar
• Isik, I. and Celik, I., 2008. Acute effects of methyl parathion and diazinon as inducers for oxidative stress on certain biomarkers in various tissues of rainbowtrout (Oncorhynchus mykiss). Pesticide Biochemistry and Physiology, 92 (1), 38–42.
   Web of Science ®Google Scholar
• Ismail, M., Al-Naqeep, G., and Chan, K.W., 2010. Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats. Free Radical Biology and Medicine, 48 (5), 664–672.
   PubMed Web of Science ®Google Scholar
• Khaksar, M.R., et al., 2017. Protective effects of cerium oxide and yttrium oxide nanoparticles on reduction of oxidative stress induced by sub-acute exposure to diazinon in the rat pancreas. Journal of Trace Elements in Medicine and Biology, 41, 79–90.
   PubMed Web of Science ®Google Scholar
• Lari, P., et al., 2015. Evaluation of diazinon-induced hepatotoxicity and protective effects of crocin. Toxicology and Industrial Health, 31 (4), 367–376.
   PubMed Web of Science ®Google Scholar
• Lotti, M., 2001. Clinical toxicology of anticholinesterase agents in humans. Handbook of Pesticide Toxicology, 2, 1043–1085.
   Google Scholar
• Marchand, M., et al., 2009. Histopathological alterations in the liver of the sharptooth catfish Clarias gariepinus from polluted aquatic systems in South Africa. Environmental Toxicology, 24 (2), 133–147.
   PubMed Web of Science ®Google Scholar
• Mehri, N., et al., 2016. Hepatoprotective effect of the root extract of green tea against malathion-induced oxidative stress in rats. Journal of Herbmed Pharmacology, 5 (3), 116–119.
   Google Scholar
• Mossa, A.-T.H., Refaie, A.A., and Ramadan, A., 2011. Effect of exposure to mixture of four organophosphate insecticides at no observed adverse effect level dose on rat liver: the protective role of vitamin C. Research Journal of Environmental Toxicology, 5 (6), 323.
   Google Scholar
• Ogutcu, A., et al., 2006. The effects of organophosphate insecticide diazinon on malondialdehyde levels and myocardial cells in rat heart tissue and protective role of vitamin E. Pesticide Biochemistry and Physiology, 86 (2), 93–98.
   Web of Science ®Google Scholar
• Oruç, E.Ö. and Usta, D., 2007. Evaluation of oxidative stress responses and neurotoxicity potential of diazinon in different tissues of Cyprinus carpio. Environmental Toxicology and Pharmacology, 23 (1), 48–55.
   PubMed Web of Science ®Google Scholar
• Razavi, B.M., et al., 2013. Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure. Chemico-Biological Interactions, 203 (3), 547–555.
   PubMed Web of Science ®Google Scholar
• Roegge, C.S., et al., 2008. Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Research Bulletin, 75 (1), 166–172.
   PubMed Web of Science ®Google Scholar
• Sayed‐Ahmed, M.M. and Nagi M.N., 2007. Thymoquinone supplementation prevents the development of gentamicin‐induced acute renal toxicity in rats. Clinical and Experimental Pharmacology and Physiology, 34 (5–6), 399–405.
   PubMed Web of Science ®Google Scholar