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Research Articles

Effect of carvedilol versus propranolol on acute and chronic liver toxicity in rats

Pages 101-111 | Received 30 Sep 2018, Accepted 16 Jan 2019, Published online: 27 Feb 2019

References

  • Alatsakis, M., et al., 2009. Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. European Surgical Research, 42 (1), 11–16.
  • Bañares, R., et al., 1999. Carvedilol, a new nonselective beta-blocker with intrinsic anti- Alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis. Hepatology, 30 (1), 79–83.
  • Bataller, R., and Brenner, D.A., 2005. Liver fibrosis. The Journal of Clinical Investigation, 115 (2), 209–218.
  • Bedossa, P., and Poynard, T., 1996. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group Hepatology, 24, 289–293.
  • Buege, J.A., and Aust, S.D., 1978. Microsomal lipid peroxidation. Methods in Enzymology, 52, 302–310.
  • Cao, B.-Q., et al., 2007. Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats. World Journal of Gastroenterology, 13 (12), 1851–1856.
  • Cheung, P.-Y., et al., 2006. Effect of WeiJia on carbon tetrachloride induced chronic liver injury. World Journal of Gastroenterology, 28 (12), 1912–1917.
  • Dubuisson, L., et al., 2002. Inhibition of rat liver fibrogenesis through noradrenergic antagonism. Hepatology (Baltimore, Md.), 35 (2), 325–331.
  • Esler, M., et al., 1992. Increased sympathetic nervous activity and the effects of its inhibition with clonidine in alcoholic cirrhosis. Annals of Internal Medicine, 116 (6), 446–455.
  • Fiorucci, S., et al., 2001. NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proceedings of the National Academy of Sciences of the United States of America, 98 (15), 8897–8902.
  • Flohé, L., and Günzler, W.A., 1984. Assays of glutathione peroxidase. Methods in Enzymology, 105, 114–121.
  • Fortune, B.E., et al., 2009. Vapreotide: a somatostatin analog for the treatment of acute variceal bleeding. Expert Opinion on Pharmacotherapy, 10 (14), 2337–2342.
  • Frautschy, S.A., et al., 2001. Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology. Neurobiology of Aging, 22 (6), 993–1005.
  • Greenwel, P., et al., 2000. Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells. Hepatology, 31 (1), 109–116.
  • Groszmann, R.J., et al., 2005. Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. New England Journal of Medicine, 353 (21), 2254–2261.
  • Hamilton, R.L., et al., 1974. A simple and inexpensive membrane "lung" for small organ perfusion. Journal of Lipid Research, 15 (2), 182–186.
  • Hoebe, K.H., et al., 2004. Endotoxin-induced liver damage in rats is minimized by beta 2-adrenoceptor stimulation. Inflammation Research, 53 (3), 93–99.
  • Lin, H.C., et al., 2004. Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis. The American Journal of Gastroenterology, 99 (10), 1953–1958.
  • Lysko, P.G., et al., 1998. Neuroprotective activitiesof carvedilol and a hydroxylated derivative, role of membrane biophysical interactions. Biochemical pharmacology, 56 (12), 1645–1656.
  • Marra, F., 1999. Hepatic stellate cells and the regulation of liver inflammation. Journal of Hepatology, 31 (6), 1120–1130.
  • Marteau, P., et al., 1989. Effect of vasodilators on hepatic microcirculation in cirrhosis: a study in the isolated perfused rat liver. Hepatology, 9 (6), 820-823.
  • Matei, V., et al., 2006. The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis. Hepatology (Baltimore, Md.), 44 (1), 44–52.
  • Matsumoto, H., et al., 2000. Role of kuppfer cells in the release of nitric oxide and change of portal pressure after ethanol perfusion in the rat liver. Alcohol and Alcoholism, 35 (1), 31–34.
  • Merrick, B.A., et al., 2006. Alterations in the rat serum proteome during liver injury from acetaminophen exposure. The Journal of Pharmacology and Experimental Therapeutics, 318 (2), 792–802.
  • Moal, F., et al., 2006. Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats. World Journal of Gastroenterology, 7 (41), 6639. 6645
  • Morishita, K., et al., 2006. Gene expression profile in liver of differing ages of rats after single oral administration of acetaminophen. The Journal of Toxicological Sciences, 31 (5), 491–507.
  • Oben, J.A., and Diehl, A.M., 2004. Sympathetic nervous system regulation of liver repair. The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 (1), 874–883.
  • Oben, J.A., et al., 2003. Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells. Biochemical and Biophysical Research Communications, 302 (4), 685–690.
  • Pérez Tamayo, R., 1983. Is cirrhosis of the liver experimentally produced by CCl4 and adequate model of human cirrhosis? Hepatology, 3, 112–120.
  • Rahman, T.M., and Hodgson, H.J., 2000. Animal models of acute hepatic failure. International Journal of Experimental Pathology, 81 (2), 145–157.
  • Ramos, B.P., et al., 2005. The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys. Biological Psychiatry, 58 (11), 894–900.
  • Randle, L.E., et al., 2008. A1-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice. British Journal of Pharmacology, 153 (4), 820–830.
  • Reynaert, H., et al., 2002. Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension. Gut, 50 (4), 571–581.
  • Rössig, L., et al., 2000. Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol. Journal of the American College of Cardiology, 36 (7), 2081–2089.
  • Sancho-Bru, P., et al., 2006. Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. American Journal of Physiology. Gastrointestinal and Liver Physiology, 291 (5), G877–G884.
  • Singh, A., et al., 2002. Effect of natural and synthetic antioxidants in a mouse model of chronic fatigue syndrome. Journal of Medicinal Food, 5 (4), 211–220.
  • Trim, N., et al., 2000. Hepatic stellate cells express the low affinity nerve growth factor receptor p75 and undergo apoptosis in response to nerve growth factor stimulation. The American Journal of Pathology, 156 (4), 1235–1243.
  • Tripathi, D., and Hayes, P.C., 2010. The role of carvedilol in the management of portal hypertension. European Journal of Gastroenterology and Hepatology, 22 (8), 905–911.
  • Tsochatzis, E.A., Triantos, C.K., and Burroughs, A.K., 2009. Gastrointestinal bleeding: carvedilol-the best beta-blocker for primary prophylaxis? Nature Reviews. Gastroenterology and Hepatology, 6 (12), 692–694.
  • Vom Dahl, S., et al., 1999. Release of osmolytes from perfused rat liver on perivascular nerve stimulation: alpha-adrenergic control of osmolyte efflux from parenchymal and nonparenchymal liver cells. Hepatology (Baltimore, Md.), 29 (1), 195–204.
  • Walldorf, J., et al., 2010. Propranolol impairs liver regeneration after partial hepatectomy in C57Bl/6-mice by transient attenuation of hepatic lipid accumulation and increased apoptosis. Scandinavian Journal of Gastroenterology, 45 (4), 468–476.
  • Wang, R., et al., 2006. Pleiotropic effects of the B adrenoceptor blocker carvedilol on calcium regulation during oxidative stress-induced apoptosis in cardiomyocytes. The Journal of Pharmacology and Experimental Therapeutics, 318 (1), 45–52.
  • Yue, T.L., et al., 1995. Carvedilol, a new vasodilating beta-adrenoceptor blocker, inhibits oxidation of low-density lipoproteins by vascular smooth muscle cells and prevents leukocyte adhesion to smooth muscle cells. The Journal of Pharmacology and Experimental Therapeutics, 273 (3), 1442–1449.
  • Yue, T.L., et al., 1998. Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circulation Research, 82 (2), 166–174.

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