References
- Abdelmageed, M.E., et al., 2019. Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/PI3K/AKT2 pathway and AGEs/RAGE interaction. Naunyn-Schmiedeberg’s Archives of Pharmacology, 392(2), 243–258.
- Bekheet, S.H., et al., 2010. Histopathological and biochemical changes of morphine sulphate administration on the cerebellum of albino rats. Tissue and Cell, 42(3), 165–175.
- Bimonte, S., et al., 2018. The effects of naloxone on human breast cancer progression: in vitro and in vivo studies on MDA.MB231 cells. Onco Targets and Therapy, 11, 185–191.
- Bodnar, R.J., 2018. Endogenous opiates and behavior: 2016. Peptides, 101, 167–212.
- Bradford, M.M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72(1–2), 248–254.
- Cakan, M., et al., 2008. Effect of naloxone on oxidative stress and testicular injury due to spermatic vessel ligation of rat testis. Urologia Internationalis, 81(3), 279–284.
- Chou, S.H., et al., 2012. Naloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway. Synapse, 66(8), 694–704.
- D’Angelo, E., 2018. Physiology of the cerebellum. Handbook of Clinical Neurology, 154, 85–108.
- Dorri, M., Hashemitabar, S., and Hosseinzadeh, H., 2018. Cinnamon (Cinnamomum zeylanicum) as an antidote or a protective agent against natural or chemical toxicities: a review. Drug and Chemical Toxicology, 41(3), 338–351.
- Farag, M.R., Alagawany, M., and Tufarelli, V., 2017. In vitro antioxidant activities of resveratrol, cinnamaldehyde and their synergistic effect against cyadox-induced cytotoxicity in rabbit erythrocytes. Drug and Chemical Toxicology, 40(2), 196–205.
- Günther, T., et al., 2018. Targeting multiple opioid receptors - improved analgesics with reduced side effects? British Journal of Pharmacology, 175(14), 2857–2868.
- He, Y.C., et al., 2012. Histamine promotes rat motor performances by activation of H2 receptors in the cerebellar fastigial nucleus. Behavioural Brain Research, 228(1), 44–52.
- Hébert, C.D., Yuan, J., and Dieter, M.P., 1994. Comparison of the toxicity of cinnamaldehyde when administered by microencapsulation in feed or by corn oil gavage. Food and Chemical Toxicology, 32(12), 1107–1115.
- Hsu, Y.Y., et al., 2014. Nanomolar naloxone attenuates neurotoxicity induced by oxidative stress and survival motor neuron protein deficiency. Neurotoxicity Research, 25(3), 262–270.
- Huang, H. and Wang, Y., 2017. The protective effect of cinnamaldehyde on lipopolysaccharide induced acute lung injury in mice. Cellular and Molecular Biology (Biology), 63(8), 58–63.
- Jalili, C., et al., 2017. Protective effect of thymoquinone against morphine injuries to kidneys of mice. Iranian Journal of Kidney Diseases, 11(2), 142–150.
- Jawale, A., et al., 2016. Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde. Phytomedicine, 23(9), 923–930.
- Jawień, W., 2014. Searching for an optimal AUC estimation method: a never-ending task? Journal of Pharmacokinetics and Pharmacodynamics, 41(6), 655–673.
- Karkhah, A., Ataee, R., and Ataie, A., 2017. Morphine pre- and post-conditioning exacerbates apoptosis in rat hippocampus cells in a model of homocysteine-induced oxidative stress. Biomedical Reports, 7(4), 309–313.
- Kim, H.K. and Nelson, L.S., 2015. Reducing the harm of opioid overdose with the safe use of naloxone: a pharmacologic review. Expert Opinion on Drug Safety, 14(7), 1137–1146.
- Koga, S., et al., 2014. In vivo subcellular imaging of tumors in mouse model using a fluorophore-conjugated anti-carcinoembryonic antigen antibody in two-photon excitation microscopy. Cancer Science, 105(10), 1299–1306.
- Lee, S.C., et al., 2018. Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice. Journal of Food and Drug Analysis, 26(1), 211–220.
- Lekic, T., et al., 2011. Characterization of the brain injury, neurobehavioral profiles, and histopathology in a rat model of cerebellar hemorrhage. Experimental Neurology, 227(1), 96–103.
- Lv, C., et al., 2017. Protective effect of cinnamaldehyde against glutamate-induced oxidative stress and apoptosis in PC12 cells. European Journal of Pharmacology, 815, 487–494.
- Mao, J., et al., 2002. Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. The Journal of Neuroscience, 22(17), 7650–7661.
- Marsden, J.F., 2018. Cerebellar ataxia. Handbook of Clinical Neurology, 159, 261–281.
- Mereto, E., et al., 1994. Cinnamaldehyde-induced micronuclei in rodent liver. Mutation Research/Genetic Toxicology, 322(1), 1–8.
- Metz, G.A., et al., 1998. The effects of unilateral pyramidal tract section on hindlimb motor performance in the rat. Behavioural Brain Research, 96(1–2), 37–46.
- Mirzakhani, N., et al., 2018. Carnosine improves functional recovery and structural regeneration after sciatic nerve crush injury in rats. Life Sciences, 215, 22–30.
- Mohamed, H.M. and Mahmoud, A.M., 2019. Chronic exposure to the opioid tramadol induces oxidative damage, inflammation and apoptosis, and alters cerebral monoamine neurotransmitters in rats. Biomedicine & Pharmacotherapy, 110, 239–247.
- Ni, Y.Q., et al., 2008. Neuroprotective effects of naloxone against light-induced photoreceptor degeneration through inhibiting retinal microglial activation. Investigative Opthalmology & Visual Science, 49(6), 2589–2598.
- Noori, S.A., et al., 2019. Nonopioid versus opioid agents for chronic neuropathic pain, rheumatoid arthritis pain, cancer pain and low back pain. Pain Management, 9(2), 205–216.
- Overstreet, D.H., et al., 1999. Suppression of alcohol intake by chronic naloxone treatment in P rats: tolerance development and elevation of opiate receptor binding. Alcoholism: Clinical & Experimental Research, 23(11), 1761–1771.
- Pan, J., et al., 2017. Activating autophagy in hippocampal cells alleviates the morphine-induced memory impairment. Molecular Neurobiology, 54(3), 1710–1724.
- Peng, J., Sarkar, S., and Chang, S.L., 2012. Opioid receptor expression in human brain and peripheral tissues using absolute quantitative real-time RT-PCR. Drug and Alcohol Dependence, 124(3), 223–228.
- Prastiwi, D., Djunaidi, A., and Partadiredja, G., 2015. High dosage of monosodium glutamate causes deficits of the motor coordination and the number of cerebellar Purkinje cells of rats. Human & Experimental Toxicology, 34(11), 1171–1179.
- Rao, P.V. and Gan, S.H., 2014. Cinnamon: a multifaceted medicinal plant. Evidence-Based Complementary and Alternative Medicine, 2014, 1.
- Salahshoor, M.R., et al., 2018. Genistein improves liver damage in male mice exposed to morphine. Chinese Medical Journal, 131(13), 1598–1604.
- Shahid, M., et al., 2017. Neuroprotective effect of Bacopa monnieri against morphine-induced histopathological changes in the cerebellum of rats. Pakistan Journal of Pharmaceutical Sciences, 30(6), 2067–2074.
- Skolnick, P., 2018. On the front lines of the opioid epidemic: rescue by naloxone. European Journal of Pharmacology, 835, 147–153.
- Stoodley, C.J. and Schmahmann, J.D., 2018. Functional topography of the human cerebellum. Handbook of Clinical Neurology, 154, 59–70.
- Subash-Babu, P., Alshatwi, A.A., and Ignacimuthu, S., 2014. Beneficial antioxidative and antiperoxidative effect of cinnamaldehyde protect streptozotocin-induced pancreatic β-cells damage in wistar rats. Biomolecules & Therapeutics, 22(1), 47–54.
- Sui, F., et al., 2010. Cinnamaldehyde up-regulates the mRNA expression level of TRPV1 receptor potential ion channel protein and its function in primary rat DRG neurons in vitro. Journal of Asian Natural Products Research, 12(1), 76–87.
- Taati, M. and Tamaddonfard, E., 2018. Ventrolateral orbital cortex oxytocin attenuates neuropathic pain through periaqueductal gray opioid receptor. Pharmacological Reports, 70(3), 577–583.
- Tamaddonfard, E. and Hamzeh-Gooshchi, N., 2010. Effect of crocin on the morphine-induced antinociception in the formalin test in rats. Phytotherapy Research, 24(3), 410–413.
- Tanaka, K., et al., 2019. Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts. Life Sciences, 22, 232–240.
- Vieira, C.M.P., et al., 2019. Pain polymorphisms and opioids: an evidence based review. Molecular Medicine Reports, 19(3), 1423–1434.
- Wang, T.Y., et al., 2014. Anti-inflammation effects of naloxone involve phosphoinositide 3-kinase delta and gamma. Journal of Surgical Research, 192(2), 599–606.
- Wang, X., et al., 2019. Naloxone attenuates ischemic brain injury in rats through suppressing the NIK/IKKα/NF-κB and neuronal apoptotic pathways. Acta Pharmacologica Sinica, 40(2), 170–179.
- Wecker, L., et al., 2013. Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia. Neuropharmacology, 73, 75–86.
- Zhao, H., et al., 2016. Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: the regulation of autophagy and ROS production. Journal of Molecular and Cellular Cardiology, 101, 11–24.
- Zhao, J., et al., 2015. Cinnamaldehyde inhibits inflammation and brain damage in a mouse model of permanent cerebral ischaemia. British Journal of Pharmacology, 172(20), 5009–5023.