187
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Effects of hyperbilirubinemia on markers of genotoxicity and total oxidant and antioxidant status in newborns

ORCID Icon, &
Pages 451-455 | Received 03 Oct 2019, Accepted 23 Dec 2019, Published online: 06 Jan 2020

References

  • Altuner Torun, Y., et al., 2017. Reduction in serum paraoxonase level in newborns with hyperbilirubinemia as a marker of oxidative stress. The Journal of Maternal-Fetal & Neonatal Medicine, 30 (19), 2297–2300.
  • American Academy of Pediatrics Subcommittee on Hyperbilirubinemia, 2004. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, 114 (1), 297–316.
  • Aycicek, A., et al., 2008. Phototherapy causes DNA damage in peripheral mononuclear leukocytes in term infants. Journal de Pediatria, 84 (2), 141–146.
  • Basu, S., et al., 2014. Lipid peroxidation, DNA damage and total antioxidant status in neonatal hyperbilirubinemia. Journal of Perinatology, 34 (7), 519–523.
  • Dani, C., et al., 2003. Plasma bilirubin level and oxidative stress in preterm infants. Archives of Disease in Childhood. Fetal and Neonatal Edition, 88 (2), F119–F123.
  • Dani, C., et al., 2004. Role of heme oxygenase and bilirubin in oxidative stress in preterm infants. Pediatric Research, 56 (6), 873–877.
  • Davutoglu, M., et al., 2008. Oxidative stress and antioxidant status in neonatal hyperbilirubinemia. Saudi Medical Journal, 29 (12), 1743–1748.
  • Dennery, P.A., et al., 1995. Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia. Free Radical Biology and Medicine, 19 (4), 395–404.
  • El-Abdin, M.Y.Z., et al., 2012. Phototherapy and DNA changes in full term neonates with hyperbilirubinemia. Egyptian Journal of Medical Human Genetics, 13 (1), 29–35.
  • Erel, O., 2004. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clinical Biochemistry, 37 (4), 277–285.
  • Erel, O., 2005. A new automated colorimetric method for measuring total oxidant status. Clinical Biochemistry, 38 (12), 1103–1111.
  • Gathwala, G., and Sharma, S., 2000. Oxidative stress, phototherapy and the neonate. The Indian Journal of Pediatrics, 67 (11), 805–808.
  • Gopinathan, V., et al., 1994. Bilirubin and ascorbate antioxidant activity in neonatal plasma. FEBS Letters, 349 (2), 197–200.
  • Halliwell, B., 1999. Establishing the significance and optimal intake of dietary antioxidants: the biomarker concept. Nutrition Reviews, 57 (4), 104–113.
  • Hirano, T., et al., 1996. 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associated with age. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 51 (5), B303–B307.
  • Kaplan, M., Bromiker, R., and Hammerman, C., 2011. Severe neonatal hyperbilirubinemia and kernicterus: are these still problems in the third millennium? Neonatology, 100 (4), 354–362.
  • Karadag, A., et al., 2009. A chromosomal-effect study of intensive phototherapy versus conventional phototherapy in newborns with jaundice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 676 (1–2), 17–20.
  • Karakukcu, C., et al., 2009. Assessment of DNA damage and plasma catalase activity in healthy term hyperbilirubinemic infants receiving phototherapy. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 680 (1–2), 12–16.
  • Kumar, A., et al., 2007. Oxidative stress in neonatal hyperbilirubinemia. Journal of Tropical Pediatrics, 53 (1), 69–71.
  • Mesbah-Namin, S.A., Shahidi, M., and Nakhshab, M., 2017. An increased genotoxic risk in lymphocytes from phototherapy-treated Hyperbilirubinemic neonates. Iranian Biomedical Journal, 21 (3), 182–189.
  • Mireles, L.C., Lum, M.A., and Dennery, P.A., 1999. Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes. Pediatric Research, 45 (3), 355–362.
  • Mohamed, W.W., and Niazy, W.H., 2012. Genotoxic effect of phototherapy in term newborn infants with hyperbilirubinemia. Journal of Neonatal-Perinatal Medicine, 5 (4), 381–387.
  • Nag, N., et al., 2009. Role of bilirubin as antioxidant in neonatal jaundice and effect of ethanolic extract of sweet lime peel on experimentally induced jaundice in rat. Indian Journal of Biochemistry & Biophysics, 46 (1), 73–78.
  • Porter, M.L., and Dennis, B.L., 2002. Hyperbilirubinemia in the term newborn. American Family Physician, 65 (4), 599–606.
  • Shahab, M.S., et al., 2008. Evaluation of oxidant and antioxidant status in term neonates: a Plausible protective role of bilirubin. Molecular and Cellular Biochemistry, 317 (1–2), 51–59.
  • Stocker, R., and Ames, B.N., 1987. Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile. Proceedings of the National Academy of Sciences of Sciences, 84 (22), 8130–8134.
  • Stocker, R., et al., 1987. Bilirubin is an antioxidant of possible physiological importance. Science, 235 (4792), 1043–1046.
  • Wiedemann, M., et al., 2003. Neonatal blood plasma is less susceptible to oxidation than adult plasma owing to its higher content of bilirubin and lower content of oxidizable fatty acids. Pediatric Research, 53 (5), 843–849.
  • Yahia, S., et al., 2015. Influence of hyperbilirubinemia and phototherapy on markers of genotoxicity and apoptosis in full-term infants. European Journal of Pediatrics, 174 (4), 459–464.
  • Yamaguchi, T., et al., 1996. Role of bilirubin as an antioxidant in an ischemia–reperfusion of rat liver and induction of heme oxygenase. Biochemical and Biophysical Research Communications, 223 (1), 129–135.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.