Toxicological assessment of a bioactive extract from Triplaris gardneriana Wedd. seeds using alternative models

References

• Allegra, E., et al., 2018. Galleria mellonella larvae allow the discrimination of toxic and non-toxic chemicals. Chemosphere, 198, 469–472.
   PubMed Web of Science ®Google Scholar
• Almeida, T.S., et al., 2017. Phenolic compounds of Triplaris gardneriana can protect cells against oxidative stress and restore oxidative balance. Biomedicine & Pharmacotherapy, 93, 1261–1268.
   PubMed Web of Science ®Google Scholar
• Almeida, T.S., et al., 2020. Evaluation of seeds ethanolic extracts of Triplaris gardneriana Wedd. using in vitro and in vivo toxicological methods. Journal of Toxicology and Environmental Health. Part A, 83 (4), 135–152.
   PubMed Web of Science ®Google Scholar
• Arantes, M.R., et al., 2020. In vitro toxicological characterisation of the antifungal compound soybean toxin (SBTX). Toxicology In Vitro: An International Journal Published in Association with Bibra, 65, 104824.
   PubMed Web of Science ®Google Scholar
• Bambino, K., and Chu, J., 2017. Zebrafish in toxicology and environmental health. Current Topics in Developmental Biology, 124, 331–367.
   PubMed Web of Science ®Google Scholar
• Bazzano, F.C.O., 2006. Aspectos éticos da pesquisa científica. In: Silva, J.V. Bioética: meio ambiente, saúde e pesquisa. 1st ed. São Paulo: Iátria, 149–180.
   Google Scholar
• Braga, R., 1976. Plantas do nordeste, especialmente do Ceara. 3rd ed. Brasil: Taxonomia vegetal.
   Google Scholar
• Calixto, J.B., 2000. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas, 33 (2), 179–189.
   PubMed Web of Science ®Google Scholar
• Cartaxo, S.L., Souza, M.M.A., and Albuquerque, U.P., 2010. Medicinal plants with bioprospecting potential used in semi-arid northeastern Brazil. Journal of Ethnopharmacology, 131 (2), 326–342.
   PubMed Web of Science ®Google Scholar
• Chanaj-Kaczmarek, J., et al., 2015. Effects of plant extract antioxidative phenolic compounds on energetic status and viability of Saccharomyces cerevisiae cells undergoing oxidative stress. Journal of Functional Foods, 16, 364–377.
   Web of Science ®Google Scholar
• Costa-Lotufo, L.V., et al., 2005. Studies of the anticancer potential of plants used in Bangladeshi folk medicine. Journal of Ethnopharmacology, 99 (1), 21–30.
   PubMed Web of Science ®Google Scholar
• Farias, D.F., et al., 2013. Antibacterial, antioxidant, and anticholinesterase activities of plant seed extracts from Brazilian semiarid region. BioMed Research International, 2013, 510736–510739.
   PubMed Web of Science ®Google Scholar
• Finney, D.J., 1971. Probit Analysis. Journal of Pharmaceutical Sciences, 60, 1432.
   Google Scholar
• Gonçalves, Í.F.S., et al., 2020. Toxicity testing of pesticides in zebrafish-a systematic review on chemicals and associated toxicological endpoints. Environmental Science and Pollution Research International, 27 (10), 10185–10204.
   PubMed Web of Science ®Google Scholar
• Harishkumar, R., et al., 2019. Toxicity and selective biochemical assessment of quercetin, gallic acid, and curcumin in Zebrafish. Biological & Pharmaceutical Bulletin, 42 (12), 1969–1976.
   PubMed Web of Science ®Google Scholar
• Horie, Y., et al., 2017. Assessment of the lethal and sublethal effects of 20 environmental chemicals in zebrafish embryos and larvae by using OECD TG 212: the lethal and sublethal effects of chemicals by using OECD TG 212. Journal of Applied Toxicology, 37 (10), 1245–1253.
   PubMed Web of Science ®Google Scholar
• Howe, K., et al., 2013. The zebrafish reference genome sequence and its relationship to the human genome. Nature, 496 (7446), 498–503.
   PubMed Web of Science ®Google Scholar
• Jayasinghe, C.D., and Jayawardena, U.A., 2019. Toxicity assessment of herbal medicine using zebrafish embryos: a systematic review. Evidence-Based Complementary and Alternative Medicine, 2019, 7272808–7272817.
   PubMed Web of Science ®Google Scholar
• Kelly, F. J., and Fussell, J. C., 2020. Metabolomics as a tool to unravel the oxidative stress-induced toxicity of ambient air pollutants. In: Sies, H, ed. Oxidative Stress. Cambridge: Elsevier, 463–488.
   Google Scholar
• Koenig, J.A., et al., 2016. Zebrafish as a model for acetylcholinesterase-inhibiting organophosphorus agent exposure and oxime reactivation. Annals of the New York Academy of Sciences, 1374 (1), 68–77.
   PubMed Web of Science ®Google Scholar
• Li, Y.H., Wang, Y.F., and Zhu, Y., 2016. [Recent advances in anti-aging study of 2,3,5,4’-tetrahydroxystilbene-2-O-beta-D-glucopyranoside-a main component of Polygonum multiflorum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 41 (2), 182–185.
   PubMedGoogle Scholar
• Lisboa, T., et al., 2019. Toxicity and antitumor activity of a thiophene–acridine hybrid. Molecules, 25 (1), 64.
   Web of Science ®Google Scholar
• Lopes Neto, J.J., et al., 2017. Impact of bioaccessibility and bioavailability of phenolic compounds in biological systems upon the antioxidant activity of the ethanolic extract of Triplaris gardneriana seeds. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 88, 999–1007.
   PubMed Web of Science ®Google Scholar
• Lopes Neto, J.J., et al., 2020a. Triplaris gardneriana seeds extract exhibits in vitro anti-inflammatory properties in human neutrophils after oxidative treatment. Journal of Ethnopharmacology, 250, 112474.
   PubMed Web of Science ®Google Scholar
• Lopes Neto, J.J., et al., 2020b. Metabolic aspects of phenolic compounds from Triplaris gardneriana seeds in the management of oxidative stress. Drug Development and Industrial Pharmacy, 46 (6), 1026–1026.
   PubMed Web of Science ®Google Scholar
• Macedo, S.K.S., et al., 2015. Identification of flavonol glycosides and in vitro photoprotective and antioxidant activities of Triplaris gardneriana Wedd. Journal of Medicinal Plants Research, 9 (7), 207–215.
   Google Scholar
• Maguire, R., Duggan, O., and Kavanagh, K., 2016. Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents. Cell Biology and Toxicology, 32 (3), 209–216.
   PubMed Web of Science ®Google Scholar
• Makarova, K., et al., 2016. Screening of toxic effects of bisphenol A and products of its degradation: Zebrafish (Danio Rerio) embryo test and molecular docking. Zebrafish, 13 (5), 466–474.,
   PubMed Web of Science ®Google Scholar
• Mandimika, T., et al., 2007. Induction of the cholesterol biosynthesis pathway in differentiated Caco-2 cells by the potato glycoalkaloid alpha-chaconine. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 45 (10), 1918–1927.
   PubMed Web of Science ®Google Scholar
• Mann, R.S., and Kaufman, P.E., 2012. Natural product pesticides: their development. Delivery and Use against Insect Vectors, 9 (2), 185–202.
   Google Scholar
• Matos, F. J. A., 1988. Introdução à Fitoquímica Experimental. Fortaleza: UFC edições.
   Google Scholar
• Maukonen, J., and Saarela, M., 2015. Human gut microbiota: does diet matter? The Proceedings of the Nutrition Society, 74 (1), 23–36.
   PubMed Web of Science ®Google Scholar
• Meng, D., et al., 2017. Antioxidant activity evaluation of dietary phytochemicals using Saccharomyces cerevisiae as a model. Journal of Functional Foods, 38, 36–44.
   Web of Science ®Google Scholar
• Mustafa, G., et al., 2017. Bioactive compounds from medicinal plants and their importance in drug discovery in Pakistan. Matrix Science Pharma, 1 (1), 17–26.
   Google Scholar
• Nagpal, I., and Abraham, S.K., 2017. Ameliorative effects of gallic acid, quercetin and limonene on urethane-induced genotoxicity and oxidative stress in Drosophila melanogaster. Toxicology Mechanisms and Methods, 27 (4), 286–292.
   PubMed Web of Science ®Google Scholar
• Nichols, C.D., 2006. Drosophila melanogaster neurobiology, neuropharmacology, and how the fly can inform central nervous system drug discovery. Pharmacology & Therapeutics, 112 (3), 677–700.
   PubMed Web of Science ®Google Scholar
• OECD. 2013. Test No. 236, Fish Embryo Acute Toxicity (FET) Test. OECD Guidelines for the Testing of Chemicals, Section 2. Paris: OECD Publishing.
   Google Scholar
• Olejnik, A., et al., 2003. New rapid method of Caco-2 cell differentiation. Methodology Food Evaluation. Polish Journal of Food and Nutrition Sciences, 12, 60–64.
   Google Scholar
• Oliveira, M.R.C., et al., 2019. GC-MS Chemical characterization and in vitro evaluation of antioxidant and toxic effects using Drosophila melanogaster model of the essential oil of Lantana montevidensis (Spreng) Briq. Medicina, 55, 194.
   Google Scholar
• Oliveira, P.V., et al., 2010. Larvicidal activity of 94 extracts from ten plant species of northeastern of Brazil against Aedes aegypti L. (Diptera: Culicidae). Parasitology Research, 107 (2), 403–407.
   PubMed Web of Science ®Google Scholar
• Pacheco-Ordaz, R., et al., 2018. Effect of phenolic compounds on the growth of selected probiotic and pathogenic bacteria. Letters in Applied Microbiology, 66, 25–31.
   PubMed Web of Science ®Google Scholar
• Panchal, K., and Tiwari, A.K., 2017. Drosophila melanogaster “a potential model organism” for identification of pharmacological properties of plants/plant-derived components. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 89, 1331–1345.
   PubMed Web of Science ®Google Scholar
• Pandey, U.B., and Nichols, C.D., 2011. Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacological Reviews, 63 (2), 411–436.
   PubMed Web of Science ®Google Scholar
• Pessoa, I.P., et al., 2016. Polyphenol composition, antioxidant activity and cytotoxicity of seeds from two underexploited Wild Licania Species: L. rigida and L. tomentosa. Molecules, 21, 1755.
   Web of Science ®Google Scholar
• Raies, A.B., and Bajic, V.B., 2016. In silico toxicology: computational methods for the prediction of chemical toxicity: computational methods for the prediction of chemical toxicity. Wiley Interdisciplinary Reviews. Computational Molecular Science, 6 (2), 147–172.
   PubMed Web of Science ®Google Scholar
• Rapeanu, G., et al., 2014. Chapter 38 – microorganism metabolic activity stimulation by polyphenols. In: Ronald Ross Watson., et al. eds, Polyphenols in Human Health and Disease. Cambridge: Elsevier, 513–521.
   Google Scholar
• Ribeiro, S.F.F., et al., 2007. A new peptide of melon seeds which shows sequence homology with vicilin: partial characterization and antifungal activity. Scientia Horticulturae, 111 (4), 399–405.
   Web of Science ®Google Scholar
• Sarmah, R., et al., 2020. Toxicity of a Synthetic Phenolic Antioxidant, Butyl Hydroxytoluene (BHT), in Vertebrate Model Zebrafish Embryo (Danio Rerio). Aquaculture Research, 51 (9), 3839–3846.
   Web of Science ®Google Scholar
• Shyur L-F., Lau A.S.Y., editor. 2012. Recent trends in medicinal plants research. 1. ed. Amsterdam: Elsevier [u.a.].
   Google Scholar
• Silva, M.Z.R., et al., 2020. Biotechnological potential of a cysteine protease (CpCP3) from Calotropis procera latex for cheesemaking. Food Chemistry, 307, 125574.
   PubMed Web of Science ®Google Scholar
• Souza, T.M., et al., 2011. Toxicity of Brazilian plant seed extracts to two strains of Aedes aegypti (Diptera: Culicidae) and nontarget animals. Journal of Medicne Entomology, 48 (4), 846–851.
   PubMed Web of Science ®Google Scholar
• Van der Zande, M., et al., 2016. Different responses of Caco-2 and MCF-7 cells to silver nanoparticles are based on highly similar mechanisms of action. Nanotoxicology, 10 (10), 1431–1441.
   PubMed Web of Science ®Google Scholar
• Yahfoufi, N., et al., 2018. The immunomodulatory and anti-inflammatory role of polyphenols. Nutrients, 10 (11), 1618.
   PubMed Web of Science ®Google Scholar
• Yang, J.B., et al., 2018. Acute toxicity screening of different extractions, components and constituents of Polygonum multiflorum Thunb. on zebrafish (Danio rerio) embryos in vivo. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 99, 205–213.
   PubMed Web of Science ®Google Scholar
• Zhang, J., et al., 2017. Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval Zebrafish (Danio Rerio). Toxicology and Applied Pharmacology, 327, 30–38.
   PubMed Web of Science ®Google Scholar
• Zwart, D., and Posthuma, L., 2005. Complex mixture toxicity for single and multiple species: proposed methodologies. Environmental Toxicology and Chemistry, 24 (10), 2665–2676.
   PubMed Web of Science ®Google Scholar