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Research Articles

Gallic acid ameliorates busulfan-induced testicular toxicity and damage in mature rats

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References

  • Abarikwu, S.O., et al., 2016. Curcumin protects against gallic acid-induced oxidative stress, suppression of glutathione antioxidant defenses, hepatic and renal damage in rats. Renal Failure, 38 (2), 321–329.
  • Abarikwu, S.O., 2014. Protective effect of quercetin on atrazine-induced oxidative stress in the liver, kidney, brain, and heart of adult wistar rats. Toxicology International, 21 (2), 148–155.
  • Abarikwu, S.O., et al., 2010. Changes in sperm characteristics and induction of oxidative stress in the testis and epididymis of experimental rats by a herbicide, atrazine. Archives of Environmental Contamination and Toxicology, 58 (3), 874–882.
  • Abarikwu, S.O., et al., 2011. Atrazine induces transcriptional changes in marker genes associated with steroidogenesis in primary cultures of rat Leydig cells. Toxicology In Vitro: An International Journal Published in Association with BIBRA, 25 (8), 1588–1595.
  • Abarikwu, S.O., et al., 2012. Rutin ameliorates cyclophosphamide-induced reproductive toxicity in male rats. Toxicology International, 19 (2), 207–214.
  • Abarikwu, S.O., et al., 2014. Combined administration of curcumin and gallic acid inhibits gallic acid-induced suppression of steroidogenesis, sperm output, antioxidant defenses and inflammatory responsive genes. The Journal of Steroid Biochemistry and Molecular Biology, 143, 49–60.
  • Abarikwu, S.O., et al., 2018. Oral administration of cadmium depletes intratesticular and epididymal iron levels and inhibits lipid peroxidation in the testis and epididymis of adult rats. Journal of Trace Elements in Medicine and Biology, 48, 213–223.
  • Abarikwu, S.O., et al., 2019. Effect of Fe and Cd co-exposure on testicular steroid metabolism, morphometry and spermatogenesis in mice. Biological Trace Element Research, 190 (1), 109–123.
  • Abarikwu, S.O., et al., 2019. Ethanolic extract of the seeds of fluted pumpkin restores spermatogenesis and protect against oxidative damage in mice treated with busulfan. Drug and Chemical Toxicology. https://doi.org/https://doi.org/10.1080/01480545.2019.1657885.
  • Abarikwu, S.O., Pant, A.B., and Farombi, E.O., 2013. Effects of quercetin on mRNA expression of steroidogenesis genes in primary cultures of Leydig cells treated with atrazine. Toxicology In Vitro: An International Journal Published in Association with BIBRA, 27 (2), 700–707.
  • Abd-Elrazek, A.M., and Ahmed-Farid, O.A.H., 2018. Protective effect of L-carnitine and L-arginine against busulfan-induced oligospermia in adult rat. Andrologia, 50 (1), e12806.
  • Ain, Q.U., et al., 2018. Antifertility effect of methanolic leaf extract of Chenopodium ambrosioides hook in male Sprague Dawley rats. Andrologia, 50 (10), e13129,
  • Aly, H.A.A., El-Beshbishy, H.A., and Banjar, Z.M., 2012. Mitochondrial dysfunction induced impairment of spermatogenesis in LPS-treated rats: modulatory role of lycopene. European Journal of Pharmacology, 677 (1–3), 31–38.
  • Anjum, S., Krishna, A., and Tsutsui, K., 2014. Inhibitory roles of the mammalian GnIH ortholog RFRP3 in testicular activities in adult mice. J Endocrinol, 223 (1), 79–91.
  • Aslam, H., et al., 1999. The cycle duration of the seminiferous epithelium remains unaltered during GnRH antagonist-induced testicular involution in rats and monkeys. Journal of Endocrinology, 161 (2), 281–288.
  • Atessahin, A., et al., 2006. Chemoprotective effect of melatonin against cisplatin-induced testicular toxicity in rats. Journal of Pineal Research, 41 (1), 21–27.
  • Badavi, M., et al., 2014. Effects of gallic acid and cyclosporine A on antioxidant capacity and cardiac markers of rat isolated heart after ischemia/reperfusion. Iranian Red Crescent Medical Journal, 16 (6), e16424,
  • Bertholle-Bonnet, V., et al., 2007. Influence of underlying disease on busulfan disposition in pediatric bone marrow transplant recipients: a nonparametric population pharmacokinetic study. Ther Drug Monit, 29 (2), 177–184.
  • Bian, Z., et al., 2012. Regulation of the inflammatory response: enhancing neutrophil infiltration under chronic inflammatory conditions. Journal of Immunology, 188 (2), 844–853.
  • Bordbar, H., et al., 2013. Stereological study of the effect of ginger's alcoholic extract on the testis in busulfan-induced infertility in rats. Iranian Journal of Reproductive Medicine, 11, 467–472.
  • Carbonell-Capella, J.M., et al., 2014. Analytical methods for determining bioavailability and bioaccessibility of bioactive compounds from fruits and vegetables: a review. Comprehensive Reviews in Food Science and Food Safety, 13 (2), 155–171.
  • Chance, B., and Maehly, A.C., 1955. Assay of catalases and peroxidases. Methods in Enzymology, 2, 764–775.
  • Chi, H., et al., 2013. Effect of genistein administration on the recovery of spermatogenesis in the busulfan-treated rat testis. Clinical and Experimental Reproductive Medicine, 40 (2), 60–66.
  • Choi, H.J., et al., 2010. Anti-human rhinovirus activity of gallic acid possessing antioxidant capacity. Phytotherapy Research: PTR, 24 (9), 1292–1296.
  • Dehghani, F., et al., 2013. Protective effects of L-carnitine and homogenized testis tissue on the testis and sperm parameters of busulfan-induced infertile male rats. Iranian Journal of Reproductive Medicine, 11 (9), 693–704.
  • Ezirim, C.Y., et al., 2019. Protective effects of Anthocleista djalonensis A. Chev root extracts against induced testicular inflammation and impaired spermatogenesis in adult rats. Molecular Biology Reports, 46 (6), 5983–5994.
  • Fernandez, C.D.B., et al., 2008. Effects of altered epididymal sperm transit time on sperm quality. International Journal of Andrology, 31 (4), 427–437.
  • Ganguli, N., et al., 2016. An efficient method for generating a germ cell depleted animal model for studies related to spermatogonial stem cell transplantation. Stem Cell Research & Therapy, 7 (1), 142,
  • Ghezzi, P., et al., 2018. Oxidative stress and inflammation induced by environmental and psychological stressors: a biomarker perspective. Antioxid Redox Signal, 28 (9), 852–872.
  • Hassan, M., et al., 1988. Pharmacokinetic and metabolic studies of busulfan in rat plasma and brain. European Journal of Drug Metabolism and Pharmacokinetics, 13 (4), 301–305.
  • Hosseini, A.N., et al., 2014. The effect of busulfan on body weight, testis weight and MDA enzymes in male rats. International Journal of Fertility and Womens’ Medicine, 2, 316–319.
  • Huang, J., et al., 2016. Methods for measuring myeloperoxidase activity toward assessing inhibitor efficacy in living systems. Journal of Leukocyte Biology, 99 (4), 541–548.
  • Huang, Y., et al., 2019. Comparative pharmacokinetics of gallic acid, protocatechuic acid, and quercitrin in normal and pyelonephritis rats after oral administration of a polygonum capitatum extract. Molecules, 24 (21), 3873.
  • Ighodaro, O.M., and Akinloye, O.A., 2018. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid. Alexandria Journal of Medicine, 54 (4), 287–293.
  • Jiang, M., et al., 2014. Characterization of nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction. Cell Research, 24 (12), 1466–1485.
  • Jung, S.W., et al., 2015. Effects of Korean Red Ginseng extract on busulfan-induced dysfunction of the male reproductive system. Journal of Ginseng Research, 39 (3), 243–249.
  • Kanatsu-Shinohara, M., et al., 2003. Functional assessment of self-renewal activity of male germline stem cells following cytotoxic damage and serial transplantation. Biology of Reproduction, 68 (5), 1801–1807.
  • Kang, Z., et al., 2017. Expression patterns and changes of the LCN2 gene in the testes of induced cryptorchidism and busulfan-treated mice. Systems Biology in Reproductive Medicine, 63 (6), 364–369.
  • Kartkaya, K., et al., 2013. Investigation of the possible protective role of gallic acid on paraoxanase and arylesterase activities in livers of rats with acute alcohol intoxication. Cell Biochemistry and Function, 31 (3), 208–213.
  • Konishi, Y., Zhao, Z., and Shimizu, M., 2006. Phenolic acids are absorbed from the rat stomach with different absorption rates. Journal of Agricultural and Food Chemistry, 54 (20), 7539–7543.
  • Lafay, S., and Gil-Izquierdo, A., 2008. Bioavailability of phenolic acids. Phytochemistry Reviews, 7 (2), 301–311.
  • Léger, F., Nguyen, L., and Puozzo, C., 2009. Exposure equivalence between IV (0.8 mg/kg) and oral (1 mg/kg) busulfan in adult patients. European Journal of Clinical Pharmacology, 65 (9), 903–911.
  • Lowry, O.H., et al., 1951. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193 (1), 265–275.
  • Misra, H.P., and Fridovich, I., 1972. The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. Journal of Biological Chemistry, 247 (10), 3170–3175.
  • Montiel, E.E., Huidobro, C.C., and Castellon, E.A., 2003. Glutathione-related enzymes in cell cultures from different regions of human epididymis. Archives of Andrology, 49 (2), 95–105.
  • Morais, M.C., et al., 2010. Suppression of TNF-α induced NFkB activity by Gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Natural Product Research, 24 (18), 1758–1765.
  • Moron, M.S., Depierre, J.W., and Mannervik, B., 1979. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochimica et biophysica acta, 582 (1), 67–78.
  • Mullane, K.M., Kraemer, R., and Smith, B., 1985. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. Journal of Pharmacological Methods, 14 (3), 157–167.
  • Myers, A.L., et al., 2017. Clarifying Busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review. Expert Opinion on Drug Metabolism & Toxicology, 13 (9), 901–923.
  • Naghizadeh, B., and Mansouri, M.T., 2015. Protective effects of gallic acid against streptozotocin-induced oxidative damage in rat striatum. Drug Research, 65 (10), 515–520.
  • Nandi, A., et al., 2019. Role of catalase in oxidative stress- and age-associated degenerative diseases. Oxidative Medicine and Cellular Longevity, 2019, 9613090.
  • Nasimi, P., et al., 2016. Cytoprotective and anti-apoptotic effects of Satureja khuzestanica essential oil against busulfan-mediated sperm damage and seminiferous tubules destruction in adult male mice. Andrologia, 48 (1), 74–81.
  • Nasimi, P., Tabandeh, M.R., and Roohi, S., 2018. Busulfan-mediated oxidative stress and genotoxicity decrease in sperm of Satureja Khuzestanica essential oil-administered mice. Systems Biology in Reproductive Medicine, 64 (5), 348–357.
  • Nayeem, N., et al., 2016. Gallic acid: a promising lead molecule for drug development. Journal of Applied Pharmacy, 08 (02), 213–217.
  • Nelson, S.K., et al., 2006. The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy. Free Radical Biology and Medicine, 40 (2), 341–347.
  • Nguyen, L., et al., 2006. Intravenous busulfan in adults prior to haematopoietic stem cell transplantation: a population pharmacokinetic study. Cancer Chemother Pharmacol, 57 (2), 191–198.
  • Njoku, R.-C.C., et al., 2019. Dietary fluted pumpkin seeds induce reversible oligospermia and androgen insufficiency in adult rats. Systems Biology in Reproductive Medicine, 65 (6), 437–450.
  • O’Shaughnessy, P.J., Hu, L., and Baker, P.J., 2008. Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells. Reproduction, 135 (6), 839–850.
  • Ohkawa, H., Ohishi, N., and Yagi, K., 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry, 95 (2), 351–358.
  • Olayinka, E., et al., 2015. Ameliorative effect of gallic acid on cyclophosphamide-induced oxidative injury and hepatic dysfunction in rats. Medical Sciences, 3 (3), 78–92.
  • Olusoji, M.J., et al., 2017. Protective effect of gallic acid on doxorubicin‐induced testicular and epididymal toxicity. Andrologia, 49 (4), e12635.
  • Oyagbemi, A.A., et al., 2016. Gallic acid protects against cyclophosphamide‐induced toxicity in testis and epididymis of rats. Andrologia, 48 (4), 393–401.
  • Panahi, M., et al., 2015. Busulfan induced azoospermia: stereological evaluation of testes in rat. Veterinary Research Forum, 6, 273–278.
  • Perrard, M.-H., et al., 2016. Compete human and rat ex vivo spermatogenesis from fresh or frozen testicular tissue. Biology of Reproduction, 95 (4), 89–10.
  • Prasad, L., et al., 2006. Effect of gallic acid on renal biochemical alterations in male Wistar rats induced by ferric nitriloacetic acid. Human & Experimental Toxicology, 25 (9), 523–529.
  • Qin, Y., et al., 2016. Testicular busulfan injection in mice to prepare recipients for spermatogonial stem cell transplantation is safe and non-toxic. PLoS One, 11 (2), e0148388.
  • Qu, N., Itoh, M., and Sakabe, K., 2019. Effects of chemotherapy and radiotherapy on spermatogenesis: the role of testicular immunology. International Journal of Molecular Sciences, 20 (4), 957.
  • Ribeiro, C.T., et al., 2014. Effect of antioxidants on outcome of testicular torsion in rats of different ages. The Journal of Urology, 191 (5 Suppl), 1578–1584.
  • Saygin, M., et al., 2016. Impact of 2.45 GHz microwave radiation on the testicular inflammatory pathway biomarkers in young rats: the role of gallic acid. Environmental Toxicology, 31 (12), 1771–1784.
  • Vahdati, A., et al., 2015. Busulfan induces apoptotic and cytotoxic effects on testis and epididymal sperm of adult male mouse following low dose treatment. International Journal of Biosciences, 5, 70–78.
  • Verma, S., Singh, A., and Mishra, A., 2013. Gallic acid: molecular rival of cancer. Environmental Toxicology and Pharmacology, 35 (3), 473–485.
  • Vijaya Padma, P., et al., 2011. Protective effect of gallic acid against lindane induced toxicity in experimental rats. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 49 (4), 991–998.
  • Yigitturk, G., et al., 2017. The antioxidant role of agomelatine and gallic acid on oxidative stress in STZ induced type I diabetic rat testes. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 87, 240–246.
  • Zangoie, R., et al., 2020. Melatonin synergistically enhances protective effect of atorvastatin against busulfan-induced spermatogenesis injuries in a rat model. Comparative Clinical Pathology, 29 (1), 161–166.
  • Zhang, H., and Forman, H.J., 2009. Redox regulation of gamma-glutamyl transpeptidase. American Journal of Respiratory Cell and Molecular Biology, 41 (5), 509–515.

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