258
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Phytochemical analysis, in silico study and toxicity profile of Cycas pectinata Buch.-Ham seed in mice

, , , &
Pages 330-342 | Received 24 Aug 2021, Accepted 15 Jan 2022, Published online: 03 Feb 2022

References

  • Al-Afifi, N.A., et al., 2018. Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats. BMC Complementary and Alternative Medicine, 18 (1), 1–14.
  • Aneela, S., et al., 2011. Acute oral toxicity studies of Pongamia pinnata and Annona squamosa on albino Wister rats. International Journal of Research in Pharmacy and Chemistry, 1 (4), 820–824.
  • Bancroft, J.D. and Gamble, M., 2002. Theory and practice of histological techniques. 5th ed. Vol. 172. Edinburgh: Churchill Livingstone Pub, 593–620.
  • Bariweni, M.W., Yibala, O.I., and Ozolua, R.I., 2018. Toxicological studies on the aqueous leaf extract of Pavetta crassipes (K. Schum) in rodents. Journal of Pharmacy &Pharmacognosy Research, 6 (1), 1–16.
  • Boas, G.R.V., et al., 2018. Preclinical safety evaluation of the ethanolic extract from guavira fruits (Campomanesia pubescens (DC) O. BERG) in experimental models of acute and short-term toxicity in rats. Food and Chemical Toxicology, 118, 1–12.
  • Brondani, J.C., et al., 2017. Evaluation of acute and subacute toxicity of hydroethanolic extract of Dolichandra unguis-cati L. leaves in rats. Journal of Ethnopharmacology, 202, 147–153.
  • Chebaibi, M., et al., 2019. Acute toxicity of plants mixture used in traditional treatment of edema and colic renal in Morocco. Scientific African, 6, e00152.
  • Cos, P., et al., 2006. Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'. Journal of Ethnopharmacology, 106 (3), 290–302.
  • Filimonov, D.A., et al., 2014. Prediction of the biological activity spectra of organic compounds using the PASS online web resource. Chemistry of Heterocyclic Compounds, 50 (3), 444–457.
  • Greenwell, M. and Rahman, P.K.S.M., 2015. Medicinal plants: their use in anticancer treatment. International Journal of Pharmaceutical Sciences and Research, 6 (10), 4103–4112.
  • Hancock, J.T., Desikan, R., and Neill, S.J., 2001. Role of reactive oxygen species in cell signalling pathways. Biochemical Society Transactions, 29 (Pt 2), 345–349.
  • Ismail, A., et al., 2020. Chemical composition and therapeutic potential of three Cycas species in brain damage and pancreatitis provoked by γ-radiation exposure in rats. Journal of Radiation Research and Applied Sciences, 13 (1), 200–214.
  • Khuraijam, J. and Singh, R., 2015. Ethnobotany of Cycas pectinata Buch. Ham. Northeast India. Encephalartos, 119, 18–23.
  • Koutsoukis, C., et al., 2019. The variation of the chemical composition of the main plant species in a subalpine grassland in northwestern Greece. Legume Science, 1 (1), e23.
  • Laishram, S., et al., 2015. Anti-diabetic molecules from Cycas pectinata Griff. traditionally used by the Maiba-Maibi. Phytomedicine, 22 (1), 23–26.
  • Leong, L.P. and Shui, G., 2002. An investigation of antioxidant capacity of fruits in Singapore markets. Food Chemistry, 76 (1), 69–75.
  • Maity, P., et al., 2009. Biological activities of crude extracts and chemical constituents of Bael. Aegle marmelos (L.) Corr. Indian Journal of Experimental Biology, 47 (11), 849–861.
  • Mukinda, J.T. and Eagles, P.F., 2010. Acute and sub-chronic oral toxicity profiles of the aqueous extract of Polygala fruticosa in female mice and rats. Journal of Ethnopharmacology, 128 (1), 236–240.
  • Nair, J.J. and van Staden, J., 2012. Isolation and quantification of the toxic methylazoxymethanol glycoside macrozamin in selected South African cycad species. South African Journal of Botany, 82, 108–112.
  • Nasri, H., et al., 2015. Antioxidant plants and diabetes mellitus. Journal of Research in Medical Sciences, 20 (5), 491–502.
  • Ng, V.A.S., et al., 2015. Chemical constituents of Cycas sancti-lasallei. Journal of Applied Pharmaceutical Science, 5 (Suppl 1), 12–17.
  • Ngaha Njila, M.I., et al., 2019. Sperm parameters quality and reproductive effects of methanolic extract of Alchornea cordifolia leaves on senescent male rats. Andrologia, 51 (9), e13359.
  • Porwal, M., et al., 2020. Evaluation of toxicity and antihyperlipidemic activity of Spondias mombin L. leaves methanolic extract in laboratory rats. Cardiovascular & Hematological Disorders Drug Targets, 20 (4), 289–296.
  • Prakash, V., et al., 2021. Phytochemicals and biological studies on Cycas revoluta Thunb.: a review. Advances in Traditional Medicine, 21 (3), 316–389.
  • Ramaiah, S.K., 2011. Preclinical safety assessment: current gaps, challenges, and approaches in identifying translatable biomarkers of drug-induced liver injury. Clinics in Laboratory Medicine, 31 (1), 161–172.
  • Tareq, A.M., et al., 2020. Chemical profiles, pharmacological properties, and in silico studies provide new insights on Cycas pectinata. Heliyon, 6 (6), e04061.
  • Teo, S., et al., 2002. A 90-day oral gavage toxicity study of d-methylphenidate and d, l-methylphenidate in Sprague–Dawley rats. Toxicology, 179 (3), 183–196.
  • Tousson, E., El-Moghazy, M., and El-Atrsh, E., 2011. The possible effect of diets containing Nigella sativa and Thymus vulgaris on blood parameters and some organs structure in rabbit. Toxicology and Industrial Health, 27 (2), 107–116.
  • Turan, Z., et al., 2019. Plant use as a traditional method by women against vaginal discharge in western Anatolia, Turkey: a qualitative research study. Journal of Herbal Medicine, 17–18, 100272.
  • Ugwah-Oguejiofor, C.J., et al., 2019. Acute and sub-acute toxicity of aqueous extract of aerial parts of Caralluma dalzielii NE Brown in mice and rats. Heliyon, 5 (1), p.e01179.
  • Zhang, J., et al., 2015. The safety of herbal medicine: from prejudice to evidence. Evidence-Based Complementary and Alternative Medicine, 2015, 1–3.
  • Zheleva-Dimitrova, D., et al., 2019. In vivo toxicity assessment of Clinopodium vulgare L. water extract characterized by UHPLC-HRMS. Food and Chemical Toxicology, 134, 110841.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.