Role of aluminum exposure on Alzheimer’s disease and related glycogen synthase kinase pathway

References

• Abeliovich, A., and Gitler, A.D., 2016. Defects in trafficking bridge Parkinson's disease pathology and genetics. Nature, 539 (7628), 207–216.
   PubMed Web of Science ®Google Scholar
• Ali, A.A., et al., 2019. Vinpocetine mitigates aluminum-induced cognitive impairment in socially isolated rats. Physiology & Behavior, 208, 112571.
   PubMed Web of Science ®Google Scholar
• Alzheimer Association 2020. 2020 Alzheimer’ s disease facts and figures. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 16 (3), 391–460. https://doi.org/10.1002/alz.12068
   Web of Science ®Google Scholar
• Alzheimer Society of Canada 2021. Risk factors for dementia | Alzheimer Society of Canada. Alzheimer Society of Canada. https://alzheimer.ca/en/about-dementia/how-can-i-prevent-dementia/risk-factors-dementia?__cf_chl_captcha_tk__=pmd_Ixrfs_MeVBISBPF1.cRIJZ2shOBMpF9oYwZy0nCO1BQ-1632065882-0-gqNtZGzNAzujcnBszQi9 [Accessed 12 April 2022].
   Google Scholar
• Armstrong, R.A., 2019. Risk factors for alzheimer disease. Folia Neuropathologica, 57 (2), 87–105. https://doi.org/10.5114/fn.2019.85929
   PubMed Web of Science ®Google Scholar
• Baydar, T., Aydin, A., and Sahin, G., 2007. Urinary profile of 6β-hydroxycortisol in workers exposed to aluminum. Biological Trace Element Research, 120 (1-3), 36–41.
   PubMed Web of Science ®Google Scholar
• Benyettou, I., et al., 2017. Aluminium-induced behavioral changes and oxidative stress in developing rat brain and the possible ameliorating role of omega-6/omega-3 ratio. Journal of Biological Sciences, 17 (3), 106–117.
   Google Scholar
• Beurel, E., Grieco, S.F., and Jope, R.S., 2015. Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases. Pharmacology & Therapeutics, 148, 114–131.
   PubMed Web of Science ®Google Scholar
• Bhat, R.V., et al., 2018. The conundrum of GSK3 inhibitors: is it the dawn of a new beginning? Journal of Alzheimer's Disease: JAD, 64 (s1), S547–S554.
   PubMed Web of Science ®Google Scholar
• Bondy, S.C., 2016. Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration. Neurotoxicology, 52, 222–229.
   PubMed Web of Science ®Google Scholar
• Chen, X.Q., and Mobley, W.C., 2019. Exploring the pathogenesis of Alzheimer disease in basal forebrain cholinergic neurons: converging insights from alternative hypotheses. Frontiers in Neuroscience, 13 (MAY), 446–418.
   PubMed Web of Science ®Google Scholar
• Cipriani, G., et al., 2011. Alzheimer and his disease: a brief history. Neurological Sciences: Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 32 (2), 275–279.
   PubMed Web of Science ®Google Scholar
• Corkins, M.R., Committee on Nutrition., et al., 2019. Aluminum effects in infants and children. Pediatrics, 144 (6), 2019–3148.
   Web of Science ®Google Scholar
• Dernegi, A. (2021). Türkiye’de 600.000 aile Alzheimer hastalığı ile mücadele ediyor. Türkiye Alzheimer Derneği. https://www.alzheimerdernegi.org.tr/2020/08/29/turkiyede-600-000-aile-alzheimer-hastaligi-ile-mucadele-ediyor/ [Accessed 12 April 2022].
   Google Scholar
• Dey, M., and Singh, R.K., 2022. Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer’s disease. Pharmacological Reports. Advance online publication. https://doi.org/10.1007/s43440-022-00353-4
   PubMed Web of Science ®Google Scholar
• Drago, D., Bolognin, S., and Zatta, P., 2008. Role of metal ions in the abeta oligomerization in Alzheimer's disease and in other neurological disorders. Current Alzheimer Research, 5 (6), 500–507.
   PubMed Web of Science ®Google Scholar
• Duggan, J.M., et al., 1992. Aluminium beverage cans as a dietary source of aluminium. The Medical Journal of Australia, 156 (9), 604–605.
   PubMed Web of Science ®Google Scholar
• Exley, C., and Clarkson, E., 2020. Aluminum in human brain tissue from donors without neurodegenerative disease: a comparison with Alzheimer’s disease, multiple sclerosis and autism. Scientific Reports, 10 (1), 1–7.
   PubMed Web of Science ®Google Scholar
• Exley, C., and House, E.R., 2011. Aluminum in the human brain. Monatshefte Für Chemie - Chemical Monthly, 142 (4), 357–363.
   Google Scholar
• Exley, C., and Vickers, T., 2014. Elevated brain aluminium and early onset Alzheimer's disease in an individual occupationally exposed to aluminium: a case report. Journal of Medical Case Reports, 8 (1), 41–44.
   PubMedGoogle Scholar
• Ferreira-Vieira, T.H., et al., 2016. Alzheimer’s disease: targeting the cholinergic system. Current Neuropharmacology, 14 (1), 101–115. https://doi.org/10.1016/j.exger.2021.111336
   PubMed Web of Science ®Google Scholar
• Flaten, T.P., 1990. Geographical associations between aluminium in drinking water and death rates with dementia (including Alzheimer's disease), Parkinson's disease and amyotrophic lateral sclerosis in Norway. Environmental Geochemistry and Health, 12 (1-2), 152–167.
   PubMed Web of Science ®Google Scholar
• Forster, D.P., et al., 1995. Risk factors in clinically diagnosed presenile dementia of the Alzheimer type: a case-control study in northern England. Journal of Epidemiology and Community Health, 49 (3), 253–258.
   PubMed Web of Science ®Google Scholar
• Gillette-Guyonnet, S., et al., 2005. Cognitive impairment and composition of drinking water in women: findings of the EPIDOS study. The American Journal of Clinical Nutrition, 81 (4), 897–902.
   PubMed Web of Science ®Google Scholar
• Gitler, A.D., Dhillon, P., and Shorter, J., 2017. Neurodegenerative disease: models, mechanisms, and a new hope. Disease Models & Mechanisms, 10 (5), 499–502.
   PubMed Web of Science ®Google Scholar
• Gu, Y., et al., 2019. GSK-3β at the crossroads in regulating protein synthesis and lipid deposition in Zebrafish. Cells, 8 (3), 205.
   PubMed Web of Science ®Google Scholar
• Gupta, V.B., et al., 2005. Aluminium in Alzheimer's disease: are we still at a crossroad? Cellular and Molecular Life Sciences: CMLS, 62 (2), 143–158.
   PubMed Web of Science ®Google Scholar
• Hampel, H., et al., 2018. The cholinergic system in the pathophysiology and treatment of Alzheimer's disease. Brain: A Journal of Neurology, 141 (7), 1917–1933.
   PubMed Web of Science ®Google Scholar
• Hampel, H., et al., 2019. Revisiting the cholinergic hypothesis in Alzheimer's disease: emerging evidence from translational and clinical research. The Journal of Prevention of Alzheimer's Disease, 6 (1), 2–15.
   PubMed Web of Science ®Google Scholar
• Hardisson, A., Universidad de La Laguna., et al., 2017. Aluminium exposure through the diet. Food Science & Nutrition, 3 (2), 1–10.
   Google Scholar
• Heemels, M.T., 2016. Neurodegenerative diseases. Nature Insight, 539 (7628), 179–179.
   Google Scholar
• Hoffmeister, L., et al., 2020. GSK3: a kinase balancing promotion and resolution of inflammation. Cells, 9 (4), 820.
   PubMed Web of Science ®Google Scholar
• House, E., et al., 2012. Aluminium, iron and copper in human brain tissues donated to the Medical Research Council's Cognitive Function and Ageing Study. Metallomics: Integrated Biometal Science, 4 (1), 56–65.
   PubMed Web of Science ®Google Scholar
• Inan-Eroglu, E., and Ayaz, A., 2018. Is aluminum exposure a risk factor for neurological disorders? Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 23 (1), 51.
   PubMed Web of Science ®Google Scholar
• Jagust, W., 2016. Is amyloid-β harmful to the brain? Insights from human imaging studies. Brain: A Journal of Neurology, 139 (Pt 1), 23–30.
   PubMed Web of Science ®Google Scholar
• John, M., et al., 2021. Aluminum and tau in neurofibrillary tangles in familial Alzheimer’ s disease. Journal of Alzheimer's Disease Reports, 5 (1), 283–294.
   PubMedGoogle Scholar
• Jope, R.S., et al., 2017. Stressed and inflamed, can GSK3 be blamed? Trends in Biochemical Sciences, 42 (3), 180–192.
   PubMed Web of Science ®Google Scholar
• Kamali, S., Sanajou, S., and Tazehzadeh, M.N., 2019. Nanomaterials in construction and their potential impacts on human health and the environment. Environmental Engineering and Management Journal, 18 (11), 2305–2318.
   Web of Science ®Google Scholar
• Kandimalla, R., et al., 2016. Understanding aspects of aluminum exposure in Alzheimer's disease development. Brain Pathology, 26 (2), 139–154.
   PubMed Web of Science ®Google Scholar
• Karran, E., and Strooper, B.D., 2021. The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics. Nature Reviews Drug Discovery, 21, 306–318. https://doi.org/10.1038/s41573-022-00391-w
   Google Scholar
• Kitagishi, Y., et al., 2014. Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease. Research and Therapy, 6 (3), 1–7. https://doi.org/10.1186/alzrt265
   Google Scholar
• Klotz, K., et al., 2017. The health effects of aluminum exposure. Deutsches Arzteblatt International, 114 (39), 653–659. https://doi.org/10.3238/arztebl.2017.0653
   PubMed Web of Science ®Google Scholar
• Krupinska, I., 2020. Aluminium drinking water treatment residuals and their toxic impact on human health. Molecules, 25 (3), 13.
   Web of Science ®Google Scholar
• Lane, C.A., Hardy, J., and Schott, J.M., 2018. Alzheimer's disease. European Journal of Neurology, 25 (1), 59–70.
   PubMed Web of Science ®Google Scholar
• Lauretti, E., et al., 2022. Glycogen synthase kinase-3 signaling in Alzheimer’s disease. Neural Regeneration Research, 1867 (8), 1666.
   Google Scholar
• Liaquat, L., et al., 2019. Acute aluminum chloride toxicity revisited: study on DNA damage and histopathological, biochemical and neurochemical alterations in rat brain. Life Sciences, 217, 202–211.
   PubMed Web of Science ®Google Scholar
• Luque, N.B., et al., 2014. Mapping the affinity of aluminum(III) for biophosphates: interaction mode and binding affinity in 1 : 1 complexes. Physical Chemistry Chemical Physics: PCCP, 16 (37), 20107–20119.
   PubMed Web of Science ®Google Scholar
• Ly, P.T.T., et al., 2013. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes. The Journal of Clinical Investigation, 123 (1), 224–235.
   PubMed Web of Science ®Google Scholar
• Ma, X., et al., 2017. MicroRNA-322 attenuates aluminum maltolate-induced apoptosis in the human SH-SY5Y neuroblastoma cell line. Molecular Medicine Reports, 16 (2), 2199–2204.
   PubMed Web of Science ®Google Scholar
• Makin, S., 2018. The amyloid hypothesis on trial. Nature, 559 (7715), S4–S7.
   PubMed Web of Science ®Google Scholar
• Martyn, C.N., et al., 1989. Geographical relation between Alzheimer’s disease and aluminum in drinking water. Lancet, 1 (8629), 59–62.
   PubMed Web of Science ®Google Scholar
• Martyn, C.N., et al., 1997. Aluminum concentrations in drinking water and risk of Alzheimer’s. Epidemiology, 8 (3), 281–286.
   PubMed Web of Science ®Google Scholar
• Maya, S., et al., 2016. Multifaceted effects of aluminium in neurodegenerative diseases: a review. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 83, 746–754.
   PubMed Web of Science ®Google Scholar
• McLachlan, D.R.C., et al., 1996. Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology, 46 (2), 401–405.
   PubMed Web of Science ®Google Scholar
• McLachlan, D.R.C., et al., 2019. Retracted article: aluminum in neurological and neurodegenerative disease. Molecular Neurobiology, 56 (2), 1531–1538.
   PubMed Web of Science ®Google Scholar
• Mendez, M.F., 2017. Early-onset Alzheimer disease. Neurologic Clinics, 35 (2), 263–281.
   PubMed Web of Science ®Google Scholar
• Mirza, A., et al., 2017. Aluminium in brain tissue in familial Alzheimer’s disease. Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements (GMS), 40, 30–36.
   PubMed Web of Science ®Google Scholar
• Miu, A.C., and Benga, O., 2006. Aluminum and Alzheimer’s disease: a new look. Journal of Alzheimer's Disease : JAD, 10 (2-3), 179–201. https://doi.org/10.3233/JAD-2006-102-306
   PubMed Web of Science ®Google Scholar
• Mold, M., et al., 2020. Aluminum and amyloid-β in familial Alzheimer's disease. Journal of Alzheimer's Disease: JAD, 73 (4), 1627–1635.
   PubMed Web of Science ®Google Scholar
• Nie, J., 2018. exposure to aluminum in daily life and Alzheimer’s disease. Advances in Experimental Medicine and Biology, 1091, 99–111. https://doi.org/10.1007/978-981-13-1370-7_6
   PubMed Web of Science ®Google Scholar
• Niu, Q., 2018. Overview of the relationship between aluminum exposure and health of human being. In Advances in experimental medicine and biology. Vol. 1091. New York LLC: Springer, 1–31. https://doi.org/10.1007/978-981-13-1370-7_1
   Google Scholar
• OECD, 2018. "Dementia prevalence", in Health at a Glance: Europe 2018: State of Health in the EU Cycle, OECD Publishing, Paris, 108-109. https://doi.org/10.1787/health_glance_eur-2018-19-en.
   Google Scholar
• Pascual, B., and Masdeu, J.C., 2016. Tau, amyloid, and hypometabolism in the logopenic variant of primary progressive aphasia. Neurology, 86 (5), 487–488.
   PubMed Web of Science ®Google Scholar
• Peineau, S., et al., 2009. A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases. Molecular Brain, 2 (1), 22. https://doi.org/10.1186/1756-6606-2-22
   PubMed Web of Science ®Google Scholar
• Pogue, A.I., et al., 2017. Selective targeting and accumulation of aluminum in tissues of C57BL/6J mice fed aluminum sulfate activates a pro- inflammatory NF-kB-microRNA-146a signaling program. Journal of Neurology and Neuro Toxicology, 1 (1), 1-10.
   Google Scholar
• Praticò, D., et al., 2002. Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 16 (9), 1138–1140.
   PubMed Web of Science ®Google Scholar
• Prema, A., et al., 2016. Fenugreek seed powder nullified aluminium chloride induced memory loss, biochemical changes, Aβ burden and apoptosis via regulating Akt/GSK3β signaling pathway. PLOS One, 11 (11), e0165955.
   PubMed Web of Science ®Google Scholar
• Rahimzadeh, M.R., et al., 2022. Aluminum poisoning with emphasis on its mechanism and treatment of intoxication. Emergency Medicine International, 2022, 1480553–1480513.
   PubMed Web of Science ®Google Scholar
• Roda, A., et al., 2022. Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease. Neural Regeneration Research, 17 (8), 1666–1674. https://doi.org/10.4103/1673-5374.332127
   PubMed Web of Science ®Google Scholar
• Rogers, M.A.M., and Simon, D.G., 1999. A preliminary study of dietary aluminium intake and risk of Alzheimer’s disease. Age and Ageing, 28 (2), 205–209.
   PubMed Web of Science ®Google Scholar
• Rondeau, V., et al., 2000. Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study. American Journal of Epidemiology, 152 (1), 59–66.
   PubMed Web of Science ®Google Scholar
• Rondeau, V., et al., 2009. Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort . American Journal of Epidemiology, 169 (4), 489–496.
   PubMed Web of Science ®Google Scholar
• Russ, T.C., et al., 2020. Aluminium and fluoride in drinking water in relation to later dementia risk. The British Journal of Psychiatry, 216 (1), 29–34.
   PubMed Web of Science ®Google Scholar
• Sanabria-Castro, A., Alvarado-Echeverría, I., and Monge-Bonilla, C., 2017. Molecular pathogenesis of Alzheimer's disease: an update. Annals of Neurosciences, 24 (1), 46–54.
   PubMed Web of Science ®Google Scholar
• Sanajou, S., Şahin, G., and Baydar, T., 2021. Aluminum in cosmetics and personal care products. Journal of Applied Toxicology, 41 (11), 1704–1718.
   PubMed Web of Science ®Google Scholar
• Sayas, C.L., and Ávila, J., 2021. GSK-3 and tau: a key duet in Alzheimer’s disease. Cells, 10 (4), 721.
   PubMed Web of Science ®Google Scholar
• Singh, A., et al., 2019. Oxidative stress: a key modulator in neurodegenerative diseases. Molecules, 24 (8), 1583–1520.
   PubMed Web of Science ®Google Scholar
• Skalny, A. v., et al., 2021. Molecular mechanisms of aluminum neurotoxicity: update on adverse effects and therapeutic strategies. Advances in Neurotoxicology, 5, 1–34.
   Google Scholar
• Thenmozhi, A.J., et al., 2015. Neuroprotective Effect of hesperidin on aluminium chloride induced Alzheimer’s disease in Wistar rats. Neurochemical Research, 40 (4), 767–776.
   PubMed Web of Science ®Google Scholar
• Tietz, T., et al., 2019. Aggregated aluminium exposure: risk assessment for the general population. Archives of Toxicology, 93 (12), 3503–3521.
   PubMed Web of Science ®Google Scholar
• Toral-Rios, D., et al., 2020. GSK3β and tau protein in Alzheimer's disease and epilepsy. Frontiers in Cellular Neuroscience, 14 (March), 19–19.
   PubMed Web of Science ®Google Scholar
• Van Dyke, N., et al., 2021. Association between aluminum in drinking water and incident Alzheimer's disease in the Canadian Study of Health and Aging cohort. Neurotoxicology, 83, 157–165.
   PubMed Web of Science ®Google Scholar
• Walz, A., et al., 2017. Molecular pathways: revisiting glycogen synthase kinase-3β as a target for the treatment of cancer. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 23 (8), 1891–1897.
   PubMed Web of Science ®Google Scholar
• Wang, X., et al., 2018. Mechanisms underlying aluminum neurotoxicity related to 14-3-3ζ protein. Toxicological Sciences: An Official Journal of the Society of Toxicology, 163 (1), 45–56.
   PubMed Web of Science ®Google Scholar
• Wang, Y., et al., 2021. Effect of aluminum combined with ApoEε4 on Tau phosphorylation and Aβ deposition. Journal of Trace Elements in Medicine and Biology, 64 (October 2020), 126700.
   PubMed Web of Science ®Google Scholar
• Wettstein, A., et al., 1991. Failure to find a relationship between mnestic skills of octogenarians and aluminum in drinking water. International Archives of Occupational and Environmental Health, 63 (2), 97–103.
   PubMed Web of Science ®Google Scholar
• WHO. (2021). WHO EMRO | Dementia | Health topics. WHO. http://www.emro.who.int/health-topics/dementia/index.html [Accessed 12 April 2022].
   Google Scholar
• Wyss-Coray, T., 2016. Ageing, neurodegeneration and brain rejuvenation. Nature, 539 (7628), 180–186.
   PubMed Web of Science ®Google Scholar
• Yumoto, S., et al., 2009. Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer’s disease. Journal of Inorganic Biochemistry, 103 (11), 1579–1584.
   PubMed Web of Science ®Google Scholar
• Yumoto, S., Kakimi, S., and Ishikawa, A., 2018. Colocalization of aluminum and iron in nuclei of nerve cells in brains of patients with Alzheimer's Disease. Journal of Alzheimer's Disease, 65 (4), 1267–1281.
   PubMed Web of Science ®Google Scholar
• Zhang, H., et al., 2016. Caspase-3 is involved in aluminum-induced impairment of long-term potentiation in rats through the Akt/GSK-3β pathway. Neurotoxicity Research, 29 (4), 484–494.
   PubMed Web of Science ®Google Scholar
• Zhang, H., et al., 2018. Aluminum trichloride-induced hippocampal inflammatory lesions are associated with IL-1β-activated IL-1 signaling pathway in developing rats. Chemosphere, 203, 170–178.
   PubMed Web of Science ®Google Scholar
• Zhang, H., et al., 2021. The GSK-3β/β-catenin signaling-mediated brain-derived neurotrophic factor pathway is involved in aluminum-induced impairment of hippocampal LTP in vivo. Biological Trace Element Research, 199 (12), 4635–4645.
   PubMed Web of Science ®Google Scholar
• Zhao, H., et al., 2013. Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation. Behavioural Brain Research, 241 (1), 228–234.
   PubMed Web of Science ®Google Scholar