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Research Articles

In vitro cytogenetic analysis of two different anti-phosphates (sevelamer hydrochloride and calcium carbonate) agents used by patients with hyperphosphatemia

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Pages 699-707 | Received 24 Mar 2022, Accepted 22 May 2022, Published online: 07 Jun 2022

References

  • Agodoa, L.Y., Jones, C.A., and Held, P.J., 1996. End-stage renal disease in the USA: data from the United States Renal Data System. American Journal of Nephrology, 16 (1), 7–16.
  • Ames, B.N., McCann, J., and Yamasaki, E., 1975. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutation Research, 31 (6), 347–364.
  • Atalay, H., Çeli̇k, A., and Ayaz, F., 2018. Investigation of genotoxic and apoptotic effects of zirconium oxide nanoparticles (20 nm) on L929 mouse fibroblast cell line. Chemico-Biological Interactions, 296, 98–104.
  • Behets, G.J., et al., 2004. Lanthanum carbonate: a new phosphate binder. Current Opinion in Nephrology and Hypertension, 13 (4), 403–409.
  • Block, G.A., et al., 2007. Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney International, 71 (5), 438–441.
  • Burke, S.K., Slatopolsky, E.A., and Goldberg, D.I., 1997. RenaGel, a novel calcium- and aluminium-free phosphate binder, inhibits phosphate absorption in normal volunteers. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 12 (8), 1640–1644.
  • Chutia, R., et al., 2021. Modulation of phosphate deficiency-induced metabolic changes by iron availability in Arabidopsis thaliana. International Journal of Molecular Sciences, 22 (14), 7609.
  • CIR, 2016. Safety assessment of carbonate salts as used in cosmetics [online]. Available from: https://www.cir-safety.org/sites/default/files/carbon122016rep.pdf. [Accessed 05 May 2022].
  • Damment, S.J., Beevers, C., and Gatehouse, D.G., 2005. Evaluation of the potential genotoxicity of the phosphate binder lanthanum carbonate. Mutagenesis, 20 (1), 29–37.
  • D'Haese, P.C., et al., 2003. A multicenter study on the effects of lanthanum carbonate (Fosrenol) and calcium carbonate on renal bone disease in dialysis patients. Kidney International, 63 (85), S73–S78.
  • EFSA, 2011. Scientific opinion on re-evaluation of calcium carbonate (E 170) as a food additive [online]. Available from: https://www.efsa.europa.eu/en/efsajournal/pub/2318. [Accessed 05 May 2022].
  • EMEA, 2005. Renagel [online]. Available from: (https://www.ema.europa.eu/en/documents/scientific-discussion/renagel-epar-scientific-discussion_en.pdf). [Accessed 05 May 2022].
  • EMEA, 2009. CHMP ASSESSMENT REPORT FOR Renvela [online]. EMEA. Available from: (http://www.ema.europa.eu/docs/en…/WC500052615.pdf. [Accessed 05 May 2022].
  • İla, H.B., et al., 2015. Evaluation of the genotoxic or mutagenic effects of thermal stress on cultured human lymphocytes. Turkish Journal of Biology, 39 (1), 98–103.
  • Kamba, A.S., et al., 2014. Biocompatibility of bio based calcium carbonate nanocrystals aragonite polymorph on NIH 3T3 fibroblast cell line. African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM, 11 (4), 31–38.
  • Li, M., et al., 2016. Phosphorus deficiency inhibits cell division but not growth in the dinoflagellate Amphidinium carterae. Frontiers in Microbiology, 7, 826–826.
  • Maron, D.M., and Ames, B.N., 1983. Revised methods for the Salmonella mutagenicity test. Mutation Research, 113 (3-4), 173–215.
  • NKF, 2003. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. American Journal of Kidney Diseases, 42 (4 Suppl 3), S1–S201.
  • OECD, 2016. Test no. 473: in vitro mammalian chromosomal aberration test. OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris, https://doi.org/10.1787/9789264264649-en.
  • Pastor, S., et al., 2018. Influence of Carnicor, Venofer, and Sevelamer on the levels of genotoxic damage in end-stage renal disease patients. Environmental and Molecular Mutagenesis, 59 (4), 302–311.
  • Peres, A.T., et al., 2009. Effect of phosphate binders on oxidative stress and inflammation markers in hemodialysis patients. Hemodialysis International. International Symposium on Home Hemodialysis, 13 (3), 271–277.
  • Pitarque, M., et al., 1999. Examination of various biomarkers measuring genotoxic endpoints from Barcelona airport personnel. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 440 (2), 195–204.
  • Rencüzoğullari, E., Parlak, S., and Ila, H.B., 2008. The effects of food protector biphenyl on sister chromatid exchange, chromosome aberrations, and micronucleus in human lymphocytes. Drug and Chemical Toxicology, 31 (2), 263–274.
  • Rodriguez-Ribera, L., 2014. Time in hemodialysis modulates the levels of genetic damage in hemodialysis patients. Environmental and Molecular Mutagenesis., 55 (4), 363–368.
  • Rothfuss, A., et al., 2000. Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families. Cancer Research, 60 (2), 390–394.
  • Russo, A., et al., 2000. Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors. Cell Biology and Toxicology, 16 (2), 91–98.
  • Sandoval, S.B., et al., 2010. Genetic damage in chronic renal failure patients is associated with the glomerular filtration rate index. Mutagenesis, 25 (6), 603–608.
  • Sandoval, S.B., et al., 2012. Genomic instability in chronic renal failure patients. Environmental and Molecular Mutagenesis, 53 (5), 343–349.
  • Schucker, J.J., and Ward, K.E., 2005. Hyperphosphatemia and phosphate binders. American Journal of Health-System Pharmacy: AJHP: Official Journal of the American Society of Health-System Pharmacists, 62 (22), 2355–2361.
  • Singh, N.P., et al., 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Experimental Cell Research, 175 (1), 184–191.
  • Spinelli, R., et al., 2020. Molecular basis of ageing in chronic metabolic diseases. Journal of Endocrinological Investigation, 43 (10), 1373–1389.
  • Stoyanova, E., et al., 2010. Oxidative DNA damage in chronic renal failure patients. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 25 (3), 879–885.
  • Stoyanova, E., et al., 2014. Base excision repair capacity in chronic renal failure patients undergoing hemodialysis treatment. Cell Biochemistry and Function, 32 (2), 177–182.
  • TUIK, 2020. Life tables, 2017-2019 [online]. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Hayat-Tablolari-2017-2019-33711  [Accessed 05 May 2022].
  • Wang, M., et al., 2017. Evaluation of the toxicity of nano-calcium carbonates and their effects on anti-heat stress in laying hens.  Journal of the Chinese Society of Animal Science, 46, 223–234.
  • WHO, 2021. Ageing and health [online]. Available from: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health. [Accessed 05 May 2022].

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