114
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Modulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential using in silico approach

ORCID Icon, , , , &
Pages 1004-1014 | Received 22 Dec 2021, Accepted 16 Apr 2022, Published online: 29 Aug 2022

References

  • Adeoye, A.O., Olanlokun, J.O., and Bewaji, C.O., 2018. Activity of apigenin and quercetin on rat hepatic mitochondrial permeability transition pore. Pharmacologyonline, 2, 11–22.
  • Adeoye, A.O., et al., 2019. Molecular docking analysis of apigenin and quercetin from ethyl acetate fraction of Adansonia digitata with malaria-associated calcium transport protein: an in silico approach. Heliyon, 5 (9), e02248.
  • Adeoye, A.O., et al., 2021. Repurposing of chloroquine and some clinically approved antiviral drugs as effective therapeutics to prevent cellular entry and replication of coronavirus. Journal of Biomolecular Structure & Dynamics, 39 (10), 3469–3479.
  • Ahmadian, E., et al., 2016. Role of renin-angiotensin system in liver diseases: an outline on the potential therapeutic points of intervention. Expert Review of Gastroenterology & Hepatology, 10 (11), 1279–1288.
  • Appaix, F., et al., 2000. Rapid spectrophotometric method for the quantitation of cytochrome c release from isolated mitochondria or permeabilized cells revisited. Biochimica et Biophysica Acta, 1457 (3), 175–181.
  • Banerjee, P., et al., 2018. ProTox-II: a webserver for the prediction of toxicity of chemicals. Nucleic Acids Research, 46 (W1), W257–W263.
  • Barry, M., and Bleackley, R.C., 2002. Cytotoxic T lymphocytes: all roads lead to death. Nature Reviews. Immunology, 2 (6), 401–409.
  • Berman, H.M., et al., 2000. The protein data bank. Nucleic Acids Research, 28 (1), 235–242.
  • Bernardi, P., et al., 2015. The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction and role in pathophysiology. Physiological Reviews, 95 (4), 1111–1155.
  • Bridi, R., et al., 2019. Honeybee pollen load: phenolic composition and antimicrobial activity and antioxidant capacity. Journal of Natural Products, 82 (3), 559–565.
  • Cai, H., Griendling, K.K., and Harrison, D.G., 2003. The vascular NAD (P) H oxidases as therapeutic targets in cardiovascular diseases. Trends in Pharmacological Sciences, 24 (9), 471–478.
  • Daina, A., Michielin, O., and Zoete, V., 2017. SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness, and medicinal chemistry friendliness of small molecules. Scientific Reports, 7, 42717.
  • Daniel, O.O., et al., 2018. Inhibition of liver mitochondrial membrane permeability transition pore opening by quercetin and vitamin E in streptozotocin-induced diabetic rats. Biochemical and Biophysical Research Communications, 504 (2), 460–469.
  • Dargan, P.I., et al., 2003. Case report: severe mercuric sulfate poisoning treated with 2, 3-dimercaptopropane-1-sulphonate and haemodiafiltration. Critical Care, 7 (3), R1–6.
  • Deepak, S., et al., 2016. Myricetin: a dietary molecule with diverse biological activities. Nutrients, 8 (2), 90.
  • Drwal, M.N., et al., 2014. ProTox: a web server for the in silico prediction of rodent oral toxicity. Nucleic Acids Research, 10, 1–6.
  • Dubois, M., et al., 2007. Glucotoxicity inhibits late steps of insulin exocytosis. Endocrinology, 148 (4), 1605–1614.
  • Enmozhi, S.K., et al., 2020. Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach. Journal of Biomolecular Structure and Dynamics, 39 (9). 92–98.
  • Fan, X.Y., et al., 2018. Mitochondrial toxicity: membrane permeability transition pore opening and respiratory dysfunction. Toxicology Research, 7 (2), 191–200.
  • Fonteh, P., et al., 2015. Impedance technology reveals correlations between cytotoxicity and lipophilicity of mono and bimetallic phosphine complexes. BioMetals, 28 (4), 653–667.
  • Garcia, C.R.S., 1999. Calcium homeostasis and signaling in the blood-stage malaria parasite. Parasitology Today, 15 (12), 488–491.
  • Hajnóczky, G., Csordás, G., and Yi, M., 2002. Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria. Cell Calcium, 32 (5-6), 363–377.
  • Hajnóczky, G., et al., 2000. The machinery of local Ca2+ signaling between sarco‐endoplasmic reticulum and mitochondria. The Journal of Physiology, 529 (1), 69–81.
  • Han, Y., et al., 2019. In silico ADME and toxicity prediction of ceftazidime and its impurities. Frontiers in Pharmacology, 10, 434.
  • Ichiye, T., and Karplus, M., 1991. Collective motions in proteins: a covariance analysis of atomic fluctuations in molecular dynamics and normal mode simulations. Proteins, 11 (3), 205–217.
  • Igbokwe, I.O., Igwenagu, E., and Igbokwe, N.A., 2019. Aluminium toxicosis: a review of toxic actions and effects. Interdisciplinary Toxicology, 12 (2), 45–70.
  • Johnson, D., and Lardy, H., 1967. Isolation of liver or kidney mitochondria. Methods in Enzymology, 10, 94–96.
  • Lapidus, R.G., and Sokolove, P.M., 1993. Spermine inhibition of the permeability transition of isolated rat liver mitochondria: an investigation of mechanism. Archives of Biochemistry and Biophysics., 306 (1), 246–253.
  • Li, C., et al., 2011. Effects of myricetin, an anticancer compound, on the bioavailability and pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats. European Journal of Drug Metabolism and Pharmacokinetics, 36 (3), 175–182.
  • Lin, S.C., and Way, E.L., 1984. A high-affinity calcium, ATPase enriched nerve ending plasma membrane activated ATPase of brain nerve ending. Journal of Neurochemistry, 42 (6), 1697–1706.
  • Lipinski, C.A., et al., 2001. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews, 46 (1–3), 3–26.
  • López-Blanco, J.R., et al., 2014. iMODS: internal coordinates normal mode analysis server. Nucleic Acids Research, 42 (Web Server issue), W271–276.
  • Lowry, O.H., et al., 1951. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry., 193, 262–275.
  • McKenzie, B.A., et al., 2020. Activation of the executioner caspase 3 and 7 promotes microglial pyroptosis in Models of multiple sclerosis. Journal of Neuroinflammation, 17 (1), 1–25.
  • Nardini, M., and Garaguso, I., 2020. Characterization of bioactive compounds and antioxidant activity of fruit beers. Food Chemistry, 305, 125437.
  • O’Boyle, N.M., et al., 2011. Open Babel: an open chemical toolbox. Journal of Cheminformatics, 3 (10), 33.
  • Oso, B.J., Adeoye, A.O., and Olaoye, I.F., 2022. Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases. Journal of Biomolecular Structure & Dynamics, 40 (1), 389–400.
  • Ruberto, G., et al., 2000. Antioxidant and antimicrobial activity of Foeniculum vulgare and Crithmum maritimum essential oils. Planta Medica, 66 (8), 687–693.
  • Sartor, L., et al., 2002. Inhibition of matrix-proteases by polyphenols: chemical insights for anti-inflammatory and anti-invasion drug design. Biochemical Pharmacology, 64 (2), 229–237.
  • Seal, A., et al., 2011. Docking study of HIV-1 reverse transcriptase with phytochemicals. Bioinformation, 5 (10), 430–439.
  • Senthilvel, P., et al., 2013. Flavonoid from Carica papaya inhibits NS2B-NS3 protease and prevents Dengue 2 viral assembly. Bioinformation, 9 (18), 889–895.
  • Song, X., et al., 2021. Myricetin: a review of the most recent research. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 134, 111017.
  • Sorkun, M.C., Khetan, A., and Er, S., 2019. AqSolDB, a curated reference set of aqueous solubility and 2D descriptors for a diverse set of compounds. Scientific Data, 6 (1), 143.
  • Sousa, M.C., et al., 2013. In silico metabolism studies of dietary flavonoids by CYP1A2 and CYP2C9. Food Research International., 50 (1), 102–110.
  • Srinivasan, B., 2012. Mitochondrial permeability transition pore: an enigmatic gatekeeper. New Horizons for Science, Technology, 1, 47–51.
  • Suleman, M., et al., 2011. Effect of lead acetate administered orally at different dosage levels in broiler chicks. African Journal of Environmental Science and Technology, 5 (12), 1017–1026.
  • Trott, O., and Olson, A.J., 2010. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. Journal of Computational Chemistry, 31 (2), 455–461.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.