Specific Determination of Hydroquinidine and Its Major Metabolites in Biological Fluids by High Performance Liquid Chromatography

References

• Flouvat , B. , Delhotal , B. , Kahn , J. C. , Crouzette , J. , Dubourg , O. , Roux , A. , Fodor , F. and Bourdarias , J. P. 1984 . Etude pharmacocinétique chez l'homme d'une formulation d'hydroquinidine à libération prolongée : administration unique et chronique . Thérapie , 39 : 337 – 344 .
   Google Scholar
• Ueda , C. T. , Williamson , B. J. and Dzindzio , B. S. 1970 . Disposition kinetics of dihydroquinidine following quinidine administration . Res. Commun. Chem. Pathol. Pharmacol. , 14 : 215 – 225 .
   Google Scholar
• Regazzi Bonora , M. , Salerno , J. A. , Rondanelli , R. , Cristiani , D. and Chimienti , M. 1982 . The bioavailability and kinetics of dihydroquinidine in patients with heart desease . Int. J. Clin. Pharmacol. , 20 : 212 – 218 .
   Google Scholar
• Camsonne , R. , Moulin , M. A. , Albessard , F. and Perault , M. 1984 . A simple fluorescence high-performance liquid chromatographic assay for dihydroquinidine in serum . Ther. Drug Monit. , 6 : 471 – 473 .
   Google Scholar
• Guentert , T. W. , Coates , P. E. , Upton , R. A. , Combs , D. L. and Riegelman , S. 1979 . Determination of quinidine and its major metabolites by high-performance liquid chromatography . J. Chromatogr. , 162 : 59 – 70 .
   PubMed Web of Science ®Google Scholar
• Guentert , T. W. , Rakhit , A. , Upton , R. A. and Riegelman , S. 1980 . An integrated approach to measurements of quinidine and metabolites in biological fluids . J. Chromatogr. , 183 : 514 – 518 .
   PubMedGoogle Scholar
• Leroyer , R. , Jarreau , C. and Pays , M. 1982 . Specific determination of quinidine and metabolites in biological fluids by reversed-phase high-performance liquid chromatography . J. Chromatogr. , 228 : 366 – 371 .
   PubMedGoogle Scholar
• Rakhit , A. , Kunitani , M. , Holford , N. H. G. and Riegelman , S. 1982 . Improved liquid-chromatographic assay of quinidine and its metabolites in biological fluids . Clin. Chem. , 28 : 1505 – 1509 .
   PubMed Web of Science ®Google Scholar
• Resplandy , G. , Mahuteau , J. , Viel , C. , Flouvat , B. and Plat , M. Synthèse des métabolites de la dihydroquinidine . Eur. J. Med. Chem. , submitted for publication
   Google Scholar
• Resplandy , G. , Mahuteau , J. , Flouvat , B. , Viel , C. and Plat , M. Identification des métabolites de la dihydroquinidine chez l'homme . Ann. Pharm. Fr. , submitted for publication
   Google Scholar
• Drayer , D. E. , Restivo , K. and Reidenberg , M. M. 1977 . Specific determination of quinidine and (3S)-3-hydroxyqui-nidine in human serum by high-pressure liquid chromatography . J. Lab. Clin. Med. , 90 : 816 – 822 .
   PubMedGoogle Scholar
• Ueda , C. T. and Nickols , J. G. 1980 . Comparative pharmacokinetics of quinidine and its O-desmethyl metabolite in rabbits . J. Pharm. Sci. , 69 : 1400 – 1403 .
   PubMed Web of Science ®Google Scholar
• Flouvat , B. , Resplandy , G. , Roux , A. , Viel , C. and Plat , M. Métabolites de la dihydroquinidine observés après administration à l'homme d'une formulation à libération prolongée . Thérapie , in press
   Google Scholar