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Original Articles

Solute Retention in Column Liquid Chromatography. XI. Exposition of the Minor-Disturbance Method of Measurement of the Void Volume

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Pages 327-332 | Published online: 16 Apr 2008

References

  • Berridge , J. C. 1986 . Techniques for the Automated Optimization of HPLC Separations , New York : Wiley .
  • Schoenmakers , P. J. 1986 . Optimization of Chromatographic Selectivity: A Guide to Method Development , Journal of Chromatography Library Vol. 35 , Amsterdam : Elsevier .
  • Laub , R. J. 1983 . “ Ch. 4 ” . In Physical Methods in Modern Chemical Analysis , Edited by: Kuwana , T. Vol. 3 , New York : Academic Press . Optimization need not in fact be carried out with capacity factors for example, Laub has pointed out that the Jones-Wellington separation factor cast solely in terms of raw retentions can be used in place of absolute as well as relative k' data for system optimization e.g. with window diagrams:,in;in Inorganic Chromatographic Analysis, MacDonald, J. C., Wiley-Interscience, New York, 1985, Ch. 2. Jones, P., and Wellington, C. A., J. Chromatogr., 213, 357 (1981)
  • Djerki , R. A. and Laub , R. J. 1987 . J. Liq. Chromatogr. , 10 : 1749 submitted for review
  • McCormick , R. M. and Karger , B. L. 1980 . Anal. Chem. , 52 : 2249
  • Slaats , E. H. , Markovski , W. , Fekete , J. and Poppe , H. 1981 . J. Chromatogr. , 207 : 299
  • Melander , W. R. , Erard , J. F. and Horvath , Cz. 1983 . J. Chromatogr. , 282 : 211
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  • Engelhardt , H. , Muller , H. and Dreyer , B. 1983 . Chromatographia , 19 : 240
  • For example, for a carrier composed of 90% methanol + 10% water . KR(i) = Ci S/Ci M (= 90% Me + 10% W)
  • Just the opposite would be true for solutes that exhibit positive deviations from Raoult's law
  • Franks , F. and Ives , D. J. G. 1966 . Quart. Rev. Chem. Soc. , 20 : 1
  • Karger , B. L. , Gant , J. R. , Hartkopf , A. and Weiner , P. H. 1976 . J. Chromatogr. , 128 : 65

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