High Performance Liquid Chromatographic Determination of Physostigmine and Its Degradation Products in Pharmaceutical Dosage Forms

References

• Hoover , J. E. , ed. Remington's Pharmaceutical Sciences, , 14th Ed. , 905 Easton, PA : Mack Printing Co. . 10842
   Google Scholar
• Davis , K. L. , Mohs , R. C. and Tinklenker , J. 1979 . Enhancement of Memory by Physostigmine . New Eng. J. Med. , 301 : 946c
   PubMed Web of Science ®Google Scholar
• De Wildt , D. J. , Porsius , A. J. and van Rooy , H. H. 1981 . Quantitative Determination of the Cholinesterase Inhibitor Physostigmine in Brain Tissue Samples Using Reversed-Phase High-Performance Liquid Chromatography . J. Chromatogr. , 225 : 381
   PubMed Web of Science ®Google Scholar
• 1980 . The United States Pharmacopeia, Twentieth Revision , Rockville, Md. : United States Pharmacopeial Convention, Inc. . Mack Publishing Co., Easton, PA. 10842, Physostigmine Salicylate Injection, p. 624, Physostigmine Sulfate Ophthalmic Solution and Physostigmine Sulfate Ophthalmic Ointment, p. 625
   Google Scholar
• Fletcher , G. and Davies , D. J. G. 1968 . The Effect of pH and Sodium Metabisulphite on the Stability of Physostigmine Sulphate Solutions to Heat and Ionizing Radiation . J. Pharm. Pharmacol. , 20 : 1085
   Google Scholar
• Tymes , N. W. 1982 . High Pressure Liquid Chromatographic Determination of Physostigmine Salicylate and Physostigmine Sulfate in Liquids and Ointments: A Collaborative Study . J. Ass. Off. Anal. Chem. , 68 : 132
   Google Scholar
• 1985 . The United States Pharmacopeia, Twenty-first Revision , Rockville, Md. : United States Pharmacopeial Convention, Inc. . Mack Publishing Co., Easton, PA. 18042, Physostigmine Salicylate Injection, p. 1878 and Physostigmine Sulfate Ophthalmic Ointment, p. 1979, Second Supplement
   Google Scholar
• Salway , A. H. 1912 . Researches on the Constitution of Physostigmine . J. Chem. Soc. , 101 : 978
   Google Scholar
• Ellis , S. 1943 . Studies on Physostigmine and Related Substances IV. Chemical Studies on Physostigmine Breakdown Products and Related Epinephrine Derivatives . J. Pharm. Expt. Ther. , 79 : 364
   Google Scholar