A Rapid Separation of Ten Carotenoids, Three Retinoids, Alpha-Tocopherol and d-Alpha-Tocopherol Acetate by High Performance Liquid Chromatography and its Application to Serum and Vegetable Samples

References

• Peto , R. , Doll , R. , Buckley , J. D. and Sporn , M. B. 1981 . Can dietary beta-carotene materially reduce human cancer rates? . Nature , 290 : 201
   PubMed Web of Science ®Google Scholar
• Willet , W. C. , Polk , B. F. , Underwood , B. A. , Stampfer , M. J. , Pressel , S , Rosner , B , Taylor , J. O. , Schneider , K and Hames , C. G. 1984 . Relation of serum vitamins A and E and carotenoids to the risk of cancer . N. Eng. J. Med. , 310 : 430
   PubMed Web of Science ®Google Scholar
• Ziegler , R. G. , Mason , T. J. , Stemhagen , A , Hoover , R , Schoenberg , J. B. , Gridley , G , Virgo , P. W. , Altman , R and Fraumeni , J. F. 1984 . Dietary carotene and vitamin A and risk of lung cancer among men in New Jersey . J.N.C.I. , 73 : 1429
   PubMed Web of Science ®Google Scholar
• Hennekens , C. H. , Mayrent , S. L. and Willet , W . 1986 . Vitamin A, carotenoids and retinoids . Cancer , 58 : 1837
   PubMed Web of Science ®Google Scholar
• Bendich , A. and Olson , J. A. 1989 . Biological actions of carotenoids . FASEB J. , 3 : 1927
   PubMed Web of Science ®Google Scholar
• Burney , P. G.J. , Comstock , G. W. and Morris , J. S. 1989 . Serologic precursors of cancer: serum micronutrients and the subsequent risk of pancreatic cancer . Am. J. Clin. Nutr. , 49 : 895
   PubMed Web of Science ®Google Scholar
• Comstock , G. W. , Bush , T. L. and Helzlsouer , K. J. Prediagnostic serum carotenoids and subsequent cancer in Washington county . Abstracts: International Conference “Antioxidant vitamins and beta-carotene in disease prevention” . Maryladn, USA. October 2–4 , London
   Google Scholar
• Cutler , R. G. 1989 . Potential role of the antioxidant vitamins and carotenoids in governing human aging rate . Abstracts: Internationsl Conference “Antioxidant vitamins and beta-carotene in disease prevention” . October 2–4 1989 , London.
   Google Scholar
• Krinsky , N. I. 1989 . Effects of carotenoids in cellular and animal systems . Abstracts: International Conference -Antioxidant vitamins and beta-carotene in disease prevention” . October, 2–4 1989 , London.
   Google Scholar
• Robertson , J. , Donner , A. P. and Trevithick , J. R. 1989 . A possible role for vitamins C and E in cataract prevention . Abstracts: International Conference “Antioxidant vitamins and beta-carotene in disease prevention” . October 2–4 1989 , London.
   Google Scholar
• Tangney , C. C. 1984 . Individual carotenoid determinations in human plasma by high-performance liquid chromatography . J. Liq. Chromatog , 7 : 2611
   Web of Science ®Google Scholar
• Bureau , J. L. and Bushway , R. J. 1986 . HPLC determination of carotenoids in fruits and vegetables in the United States . J. Food Science , 51 : 128
   Web of Science ®Google Scholar
• Stacewicz-Sapuntzakis , M , Bowen , P. E. , Kikendall , J. W. and Burgess , M. 1987 . Simultaneous determination of serum retinol and various carotenoids: their distribution in middle-aged men and women . J. Micronut. Anal. , 3 : 27
   Web of Science ®Google Scholar
• Heinonen , M. I. , Ollilainen , V. , Linkola , E. K. , Varo , P. T. and Koivistoinen , P. E. 1989 . Carotenoids in Finnish foods: vegetables, fruits, and berries . J. Agric. Food Chem. , 37 : 655
   Web of Science ®Google Scholar
• Krinsky , N. and Deneke , S. M. 1982 . Interaction of oxygen and oxy-radicals with carotenoids . J.N.C.I , 69 : 205
   PubMed Web of Science ®Google Scholar
• Khachik , F. , Beecher , G. R. and Whittaker , N. F. 1986 . Separation, identification, and quantification of the major carotenoid and chlorophyll constituents in extracts of several green vegetables by liquid chromatography . J. Agric. Food Chem. , 34 : 603
   Web of Science ®Google Scholar
• Mathews-Roth , M. M. 1982 . Antitumor activity of beta-carotene, canthaxanthin and phytoene . Oncology , 39 : 33
   PubMed Web of Science ®Google Scholar
• Simpson , K. L. and Chichester , C. O. 1981 . Metabolism and nutritional significance of carotnoids . Ann. Rev. Nutr. , 1 : 351
   PubMed Web of Science ®Google Scholar
• Peto , R. 1989 . Methodological difficulties in the interpretation of prevention trials and epidemiological studies . Abstracts: International Conference “Antioxidant vitamins and beta-carotene in disease prevention” . October 2–4 1989 , London.
   Google Scholar
• Beecher , G. R. and Khachik , F. 1984 . Evaluation of vitamin A and carotenoid data in Food Composition Tables . J.N.C.I. , 73 : 1397
   PubMed Web of Science ®Google Scholar
• Khachik , F. and Beecher , G. R. 1988 . Separation and identification of carotenoids and carotenol fatty acid esters in some squash products by liquid chromatography. 1. Quantification of carotenoids and related esters by HPLC . J. Agric. Food Chem , 36 : 929
   Web of Science ®Google Scholar
• Katrangi , N , Kaplan , L. A. and Stein , E. A. 1984 . Separation and quantitation of serum beta-carotene and other carotenoids by high performance liquid chromatography . J. Lipid Research , 25 : 400
   PubMed Web of Science ®Google Scholar
• Bieri , J. G. , Brown , E. D. and Smith , J. C. 1985 . Determination of individual carotenoids in human plasma by high performance liquid chromatography . J. Liq. Chromatog. , 8 : 473
   Web of Science ®Google Scholar
• Nierenberg , D. W. 1985 . Serum and plasma beta-carotene levels measured with an improved method of high-performance liquid chromatography . J. Chromatog. , 339 : 273
   PubMedGoogle Scholar
• Gatautis , V. J. and Pearson , K. H. 1987 . Separation of plasma carotenoids and quantitation of beta-carotene using HPLC . Clin Chim Acta , 166 : 195
   PubMedGoogle Scholar
• Ito , Y , Sasaki , R , Minohara , M , Otani , M and Aoki , K . 1987 . Quantitation of srum carotenoid concentrations in healthy inhabitants by high performance liquid chromatography . Clin Chim Acta , 169 : 197
   PubMedGoogle Scholar
• Cavina , G. , Gallinella , B. , Porr , R. , Pecora , P. and Suraci , C . 1988 . Carotenoids, retinoids and alpha-tocopherol in human serum: identification and determination by reversed-phase HPLC . J. Pharm. Biomed. Anal , 6 : 259
   PubMedGoogle Scholar
• Sowell , A. L. , Huff , D. L. , Gunter , E. W. and Driskell , W. J. 1988 . Identification of cis-carotenoids in human sera analyzed by reversed-phase high-performance liquid chromatography with diode array detection . J. Chromatog , 431 : 424
   PubMed Web of Science ®Google Scholar
• De Ritter , E. and Purcell , A. E. 1981 . Carotenoids as colorants and vitamin A precursors , Edited by: Bauernfeind , J. C. 883 London : Academic Press .
   Google Scholar
• Windholz , M. , Budavari , E. , Blumetti , R. F. and Otterbein , E. O. , eds. 1983 . The Merck Index
   Google Scholar
• Bushway , R. J. and Wilson , A. M. 1982 . Determination of alpha and beta-carotene in fruit and vegetables by high performance liquid chromatography . Can. Inst. Food Sci. Technol. J. , 15 : 165
   Web of Science ®Google Scholar
• Khachik , F. and Beecher , G. R. 1988 . Separation of carotenol fatty acid esters by high-performance liquid chromatography . J. Chromatog , 449 : 119
   PubMedGoogle Scholar
• Ohmacht , R , Tath , Gy. and Voigt , G. 1986 . HPLC determination of carotenoids in human serum by gradient elution technique . Chromatog , 22 : 189
   Google Scholar
• Ohmacht , R , Tath , Gy. and Voight , G. 1987 . Separation of serum carotenoids and vitamin A on chromsil-amino and -cyano phases by a bi-directional gradient elution technique . J. Chromatog , 395 : 609
   PubMedGoogle Scholar
• Krinsky , N. I. and Welankiwar , S. 1984 . Assay of carotenoids . Methods in enzimology , 105 : 155
   PubMed Web of Science ®Google Scholar
• Broich , C. R. , Gerber , L. E. and Erdman , J. W. 1983 . Determination of lycopene, alpha and beta-carotene and retinyl esters in human srum by reversed-phase high performance liquid chromatography . Lipids , 18 : 253
   PubMed Web of Science ®Google Scholar
• Peng , Y and Beaudry . 1983 . High-performance liquid chromatography of the provitamin A beta-carotene in plasma . J. Chromatog , 273 : 410
   PubMed Web of Science ®Google Scholar
• Driskell , W. J. , Bashor , M. M. and Neese , J. W. 1983 . Beta-carotene determined in serum by liquid chromatography with an internal standard . Clin. Chem , 29 : 1042
   PubMed Web of Science ®Google Scholar
• Nelis , H. J.C.F. and De Leenheer , A. P. 1983 . Isocratic nonaqueous reversed-phase liquid chromatography of carotenoids . Anal. Chem. , 55 : 270
   Web of Science ®Google Scholar
• Driskell , W. J. , Neese , J. W. , Bryant , C. C. and Bashor , M. M. 1982 . Measurenebt if vutanub A and vitamin E in human serum by HPLC . J. Chromatog , 231 : 439
   PubMed Web of Science ®Google Scholar
• Ziegler , R. G. 1989 . Carotenoid intake and risk of cancer . Abstracts: International confrence “Antioxidant vitamins and beta-carotene in disease prevention” . October 2–4 1989 , London.
   Google Scholar