A Simple and Rapid Reversed Phase High Performance Liquid Chromatographic Method for Quantification of Alprazolam and α-Hydroxyalprazolam in Plasma

References

• Dawson , G. W. , Jue , S. G. and Brogden , R. N. 1984 . Alprazolam a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression . Drugs , 27 : 132 – 147 .
   PubMed Web of Science ®Google Scholar
• Rickels , K. 1981 . Recent advances in anxiolytic therapy . J. Clin. Psychiatry , 42 : 40 – 43 .
   PubMedGoogle Scholar
• Feighner , J. P. , Aden , G. C. Fabre , L. F. 1983 . Comparison of alprazolam, imipramine and placebo in the treatment of depression . J. Am. Med. Assoc. , 249 : 3057 – 3064 .
   PubMed Web of Science ®Google Scholar
• Feighner , J. P. 1983 . The-new generation of antidepressants . J. Clin. Psychiatry , 44 : 49 – 55 .
   PubMed Web of Science ®Google Scholar
• Fabre , L. F. and McLendon , D. M. 1980 . A double-blind study comparing the efficacy and safety of alprazolam with imipramine and placebo in primary depression Curr . Ther. Res. , 21 : 474 – 482 .
   Google Scholar
• Gonzalez , E. R. 1982 . Panic disorder may respond to new antidepressants . J. Am. Med. Assoc. , 248 : 3077 – 3087 .
   PubMedGoogle Scholar
• McCormick , S. R. , Nielsen , J. and Jatlow , P. 1984 . Quantification of alprazolam in serum or plasma by liquid chromatography . Clin. Chem. , 30 ( 10 ) : 1652 – 1655 .
   PubMed Web of Science ®Google Scholar
• Adams , W. J. , Bombardt , P. A. and Brewer , J. E. 1984 . Normal-phase liquid chromatographic determination of alprazolam in human serum . Anal. Chem. , 56 : 1590 – 1594 .
   PubMedGoogle Scholar
• Greenblatt , D. J. , Divoll , M. , Moschitto , L. J. and Shader , R. I. 1981 . Electron-capture gas chromatographic analysis of the triazolobenzodiazepines alprazolam and triazolam . J. Chromatogr. (Biomedical Applications) , 225 : 202 – 207 .
   PubMedGoogle Scholar
• Miller , R. L. and DeVane , C. L. 1988 . Alprazolam, a-hydroxy-and 4-hydroxyalprazolam analysis in plasma by high-performance liquid chromatography . J. Chromatogr. (Biomedical Applications) , 430 : 180 – 186 .
   PubMedGoogle Scholar
• Adams , W. J. 1979 . Specific and sensitive high performance liquid chromatographic determination of alprazolam or triazolam . Anal. Lett. , 12 ( B6 ) : 657 – 671 .
   Google Scholar
• Theis , D. L. and Bowman , P. B. 1983 . Development of a liquid chromatographic method for the determination of triazolo-benzodiazepines . J. Chromatogr. , 268 : 92 – 98 .
   Google Scholar
• Fraser , A. D. 1987 . Urinary screening for alprazolam, triazolam, and their metabolites with the EMIT(R) d. a. u. T M benzodiazepine metabolite assay . J. Anal. Toxicol. , 11 ( 6 ) : 263 – 266 .
   PubMed Web of Science ®Google Scholar
• Fraser , A. D. and Bryan , W. 1991 . Evaluation of the Abbott ADx and TDx serum benzodiazepine immunoassays for analysis of alprazolam . J. Anal. Toxicol. , 15 ( 2 ) : 63 – 65 .
   PubMed Web of Science ®Google Scholar
• Cho , M. J. , Scahill , T. A. and Hester , J. B. 1983 . Kinetics and equilibrium of the reversible alprazolam ring-opening reaction . J. Pharm. Sci. , 72 : 356 – 361 .
   PubMed Web of Science ®Google Scholar
• Abernethy , D. R. , Greenblatt , D. J. , Divoll , M. and Shader , R. I. 1983 . Pharmacokinetics of alprazolam . J. Clin. Psychiatry , 44 : 45 – 47 .
   PubMedGoogle Scholar
• Greenblatt , D. J. , Divoll , M. , Abernethy , D. R. and Shader , R. I. 1983 . Clinical pharmacokinetics of alprazolam, a triazolo benzodiazepine. Chap. 26 in The Affective Disorders , Edited by: Davis , JM and Maas , JW . 367 – 378 . Washington, DC : American Psychiatric Press, Inc .
   Google Scholar
• Eberts , F. S. , Philopaulos , Y. , Reineke , L. M. and Vliek , R. W. 1980 . Disposition of 14C-alprazolam, a new anxiolytic antidepressant in man . Pharmacologist , 22 : 279
   Google Scholar
• Edinboro , L. E. and Backer , R. C. 1985 . Preliminary report on the application of a high performance liquid chromatographic method for alprazolam in postmortem blood specimens . J. Anal. Toxicol. , 9 ( 5 ) : 207 – 208 .
   PubMed Web of Science ®Google Scholar