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Original Articles

Determination of Chlormezanone in Plasma and Urine by High Performance Liquid Chromatography

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Pages 1747-1755 | Received 09 Jan 1991, Accepted 01 Mar 1991, Published online: 23 Oct 2006

References

  • McChesney , E. W. , Banks , W. F. , Portmann , G. A. and Grain , A. V. R. 1967 . Metabolism of chlormezanone in man and laboratory animals . Biochem. Pharmacol. , 16 : 813
  • Hakusui , H. , Tachizawa , H. and Sano , M. 1978 . Biotransformation of Chlormezanone, 2- (4-chloro-phenyl)-3-methyl-4-metathiazanone-1, 1-dioxide, a muscle-relaxing and tranquillizing agent: the effect of combination with aspirin on its metabolic fate in rats and mice . Xenobiotica , 8 : 229
  • Köppel , C. , Tenczer , J. and Wagemann , A. 1986 . Metabolism of chlormezanone in man . Arzneim.-Forsch./Drug Res. , 36 : 1116
  • Ali , S. L. and Blume , H. 1987 . Determination of chlormezanone in human plasma after administration of chlormezanone formulations . Arzneim.- Forsch./ Drug Res. , 37 : 1396
  • Gautier , V. , Vinčon , G. , Demotes-Mainard , F. and Albin , H. 1990 . Pharmacocinetique de la chlormezanone chez le volontaire sain . Therapie , 45 : 315
  • Dixon , L. and Furey , E. 1980 . an automated high pressure liquid chromatographic method for estimating 0–8 μg ml-1 chlormezanone in plasma - assay validation. Confidential report from Sterling Winthrop laboratories .

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