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Archives of Andrology
Journal of Reproductive Systems
Volume 49, 2003 - Issue 2
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Research Article

RELATION BETWEEN IMMUNOSUPPRESSIVE PGE 2 AND IL-10 TO PRO-INFLAMMATORY IL-6 IN SEMINAL PLASMA OF INFERTILE AND FERTILE MEN

M.I. CAMEJO Universidad Simón Bolívar, Departamento de Biología de Organismos, Caracas, Venezuela
Pages 111-116 | Published online: 09 Jul 2009

  • Alexander NJ, Anderson DJ (1987): Immunology of semen. Fertil Steril 47:192-205.
  • Alexander RB, Ponniah S, Hasday J, Hebel R (1998): Elevated levels of proinflammatory cytokines in the semen of patients with chronic prostatitis/chronic pelvic pain syndrome. Urology 52:744-749.
  • Camejo MI, Segnini A, Proverbio F (2001): Interleukin-6 (IL-6) in seminal plasma of infertile men, and lipid peroxidation of their sperm. Arch Androl 47:97-101.
  • Depuydt CE, Bosnians E, Zalata A, Schooonjans F, Comhaire FU (1996): The relation between reactive oxygen species and cytokines in andrological patients with or without male accessory gland infection. J Androl 17:699-707.
  • Ding L, Linsley PS, Huang LY (1993): IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up regulation of B7 expression. J Immunol 151:1224-1234.
  • Egger-Kruse W, Boit R, Rohr G, Aufenanger J, Hund M, Strowitzki T (2001): Relationship of seminal plasma interleukin (IL)-S and IL-6 with semen quality. Hum Reprod 16:517-528.
  • Groux H, Bigler M, de Vries JE, Roncarolo MG (1996): Interleukin-10 induces a long term antigen-specific anergic stated in human CD4+ T cells. J Exp Med 184:19-29.
  • Gruschwitz MS, Brezinschek R, Brezinschek HP (1996): Cytokine levels in the seminal fluid of infertile men. J Androl 17:158-163.
  • Huleihel M, Levy A, Lunenfeld E, Horowitz S, Potashnik G, Glezerman M (1997): Distinct expression of cytokines and mitogenic inhibitory factors in semen of fertile and infertile men. Am J Reprod Immunol 37:304-309.
  • Huleihel M, Lunenfeld E, Horowitz S, Levy A, Potashnik G, Mazor M, Glezerman M (1999): Expression of IL-12, IL-10, PGE2, sIL-2R and sIL-6R in seminal plasma of fertile and infertile men. Andrologia 31:283-288.
  • Imade GE, Baker HWG, de Kretser DM, Hedger MP (1997): Immunosuppressive activities in the seminal plasma of infertile men: relationship to sperm antibodies and auto immunity. Hum Reprod 12:256-262.
  • Kelly RW, Critchley HOD (1997): Immunomodulation by human seminal plasma: a benefit for spermatozoon and pathogen. Hum Reprod 12:2200-2207.
  • Kelly RW, Holland P, Skibinski G, Harrison C, McMillan L, Hargreave T, James K (1991): Extracellular organelles (prostasomas) are immunosuppressive components of human semen. Clin Exp Immunol 86:550-556.
  • Lord EM, Sensabaugh GF, Stites DP (1977): Immunosuppressive activity of human seminal plasma, I: inhibition of in vitro Lymphocyte activation. J Immunol 118:1704-1711.
  • Metalliotakis I., Kiriakou D, Fragouli I, Sifakis S, Eliopoulos G, Koumantakis E (1998): Interleukin-6 in seminal plasma of fertile and infertile men. Arch Androl 41:43-50.
  • Naz RK, Evans L (1998): Presence and modulation of interleukin-12 in seminal plasma of infertile and fertile me. J Androl 19:302-307.
  • Nocera M, Chu TM (1993): Transforming growth ß as an immunosuppressive protein in human seminal plasma. Am J Reprod Immunol 30:1-8.
  • Purvis K, Christiansen E (1996): The impact of infection on sperm quality. Hum Reprod 11:31-41.
  • Qualyle AJ, Kelly RW, Hargreave TB, James K (1989): Immunosuppression by seminal prostaglandins. Clin Exp Immunol 75:387-391.
  • Quan CP, Roux C, Pillot J, Bouvet JP (1990): Delineation between T and B suppressive molecules from human seminal plasma: spermine is the major suppressor of T lymphocytes in vitro. Am J Reprod Immunol 22:62-69.
  • Rajasekaran M, Hellstrom W, Sikka S (1996): Quantitative assessment of cytokines (GROa and IL-10) in human seminal plasma during genitourinary inflammation. Am J Reprod Immunol 36:90-95.
  • Rajasekaran M, Hellstrom WJG, Naz RK, Sikka SC (1995): Oxidative stress and interleukins in seminal plasma during leukocytospermia. Fertil Steril 64:166-171.
  • Robertson SA, Sharkey DJ (2001): The role of semen in induction of maternal immune tolerance to pregnancy. Semin Inmunol 13:243-254.
  • Saez JM (1994): Leydig cells: endocrine, paracrine and autocrine regulation. Endocr Rev 15:574-626.
  • Sakin-Kaindl F, Wagenknecht DR, Strowitzki T, Mclntyre JA, Thaler CJ (2001): Decreased suppression of antibody-dependent cellular cytotoxicity by seminal plasma in unexplained infertility. Fertil Steril 75:581-587.
  • Zalata A, Hafez T, Van Hoecke MJ, Comhaire F (1995): Evaluation of ß-endorphin and interleukin-6 in seminal plasma of patients with certain andrological diseases. Hum Reprod 10:3161-3165.

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