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Journal of Sex Education and Therapy Volume 26, 2001 - Issue 3: Special Issue on Cancer and Sexuality
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Original Articles

Sexuality and Chronic Pain

Megan P. FlemingBeth Israel Medical Center, New York, NYCorrespondence[email protected]
&
Judith A. PaiceNorthwestern University, Chicago, IL
Pages 204-214 | Published online: 21 Jan 2015

  • Abs, R., Verhelst, J., Maeyaert, J., Van Buyten., J. P., Oposomer, F., Adriaensen, H., Verlooy, J., Van Havenbergh, T., Smet, M. & Van Acker, K. (2000). Endocrine consequences of long-term intrathecal administration of opioids. Journal of Clinical Endocrinology & Metabolism, 85, 2215–2222.
  • American Cancer Society. (1997). The pain challenge. In G. P. Murphy, L. B. Morris & D. Lange (Eds.), Informed decisions. New York: Viking.
  • American Pain Society. (1999). Principles of analgesic use in the treatment of acute pain and cancer pain (4th edition). Glenview, IL: American Pain Society.
  • Ansari, A. (2000). The efficacy of newer antidepressants in the treatment of chronic pain: A review of current literature. Harvard Review of Psychiatry, 7 (5), 257–277.
  • Atkinson, J. H., Ingram, R. E., Kremer, E. F. & Saccuzzo, D. P. (1986). MMPI subgroups and affective disorders in chronic pain patients. Journal of Nervous and Mental Disease, 174 (7), 408–413.
  • Bartlik, B. D., Kaplan, P. & Kaplan, H. S. (1995). Psychostimulants apparently reverse sexual dysfunction secondary to selective serotonin re-uptake inhibitors. Journal of Sex & Marital Therapy, 21 (4), 264–271.
  • Basson, R., McInnes, R., Smith, M. D., Hodgson, G., Spain, T. & Koppiker, N. (2000). Efficacy and safety of sildenafil in estrogenized women with sexual dysfunction associated with female sexual arousal disorder. Obstetrics & Gynecology, 95 (4), S54.
  • Bredart, A., Didier, F., Robertson, C., Scaffidi, E., Fonzo, D., Costa, A., Goldhirsch, A. & Autier, P. (1999). Psychological distress in cancer patients attending the European Institute of Oncology in Milan. Oncology, 57, 297–302.
  • Brock, L. & Lue, T. F. (1993). Drug-induced male sexual dysfunction. Drug Safety, 8 (6), 414–426.
  • Bruera, E., Chadwick, S., Brenneis, C., Hanson, J. & MacDonald, R.N. (1987). Methylphenidate associated with narcotics for the treatment of cancer pain. Cancer Treatment Report, 71, 67–70.
  • Brunet, M., Rodamilans, M., Martinez-Osaba, M. J., Rodamilans, M., Martinez-Osaba, M. J., Santamaria, J., To-Figueras, J., Torra, M., Corbella, J. & Rivera, F. (1995). Effects of long-term antiepileptic therapy on the catabolism of testosterone. Pharmacology & Toxicology, 76, 371–375.
  • Buckley, F. P. (2001). Regional anesthesia with local anesthetics. In J. D. Loweser, S. H. Butler, C. R. Chapman & D. C. Turk (Eds.), Bonica's management of pain (pp 1893–1952). Philadelphia: Lippincott Williams & Wilkins.
  • Buffum, J. (1982). Pharmacosexology: The effects of drugs on sexual function. Journal of Psychoactive Drugs, 14 (1-2), 5–44.
  • Bush, K. & Hillier, S. (1991). A controlled study of caudal epidural injections of triamcinolone plus procaine for the management of intractable sciatica. Spine, 16, 572–575.
  • Butler, S. H. & Charlton, J. E. (2001). Neurolytic blockade and hypophysectomy. In J. D. Loweser, S. H. Butler, C. R. Chapman, & D. C. Turk (Eds.), Bonica's management of pain (pp 1967–2006). Philadelphia: Lippincott Williams & Wilkins.
  • Catlin, D. H., Poland, R.E., Gorelick, D.A., Gerner, R. H., Hui, K. K., Rubin, R. T. & Li, C. H. (1980). Intravenous infusion of β-endorphin increases serum prolactin, but not growth hormone or cortisol, in depressed subjects and withdrawing methadone addicts. Journal of Clinical Endocrinology and Metabolism, 50, 1021–1025.
  • Cherny, N. I. & Portenoy, R. K. (1994). The management of cancer pain. Cancer, 44 (5), 263–303.
  • Cherny, N. I. (1998). Cancer pain: Principles of assessment and syndromes. In Berger, A. M., Portenoy, R. K. & Weissman, D. E. (Eds), Principles and practice of supportive oncology. Philadelphia: Lippincott-Raven Publishers.
  • Cicero, T. H., Bell, R. D., Wiest, W. G., Allison, J. H., Polakoski, K. & Robins, E. (1975). Function of the male sex organs in heroin and methadone users. New England Journal of Medicine, 292, 882–887.
  • Clark, D. J. & Elliott, J. (1999). Gabapentin-induced anorgasmia. Neurology, 53 (9), 2209.
  • Davis, S. R. (1999). Androgen treatment in women. Medical Journal of Australia, 170 (11), 545–549.
  • De Leon, G. & Wexler, H. K. (1973). Heroin addiction: Its relation to sexual behavior and sexual experience. Journal of Abnormal Psychology, 81, 36–38.
  • Delitala, G., Grossman, A. & Besser, G. M. (1983). The participation of hypothalamic dopamine in morphine-induced prolactin release in man. Clinical Endocrinology, 19, 437–444.
  • Derogatis, L. R. & Kourlesis, S. M. (1981). An approach to the evaluation of sexual problems in the cancer patient. Cancer, 31, 46–50.
  • Derogatis, L. R., Morrow, G. R., Fetting, J., Penman, D., Schmale, A.M., Henrichs, M. & Carnicke, C. L. Jr. (1983). Prevalence of psychiatric disorders among cancer patients. Journal of the American Medical Association, 249, 751–757.
  • Derogatis, L. R., Fleming, M. P., Sudler, N. & Dellapietra, L. (1995). Psychological assessment in chronic illness. In P. Nicassio & T. W. Smith (Eds.), Psychological management of chronic illness. Washington, DC: American Psychological Association.
  • Devor, M., Govrin-Lippmann, R. & Raber, P. (1985). Corticosteroids suppress ectopic neural discharge originating in experimental neuromas. Pain, 22, 127–137.
  • Eckstein, K. L., Vicente-Eckstein, A. & Lanz, E. (1992). Sexuality following spinal anesthesia: A retrospective study of young men (less than 55 years old). Anaesthetist, 41, 63–70.
  • Ellingboe, J., Mendelson, J. H. & Kuehnle, J. C. (1980). Effects of heroin and naltrexone on plasma prolactin levels in man. Pharmacology, Biochemistry & Behavior, 12, 163–165.
  • Fava, M., Rankin, M. A., Alpert, J. E., Nierenberg, A. A. & Worthington, J. J. (1998). An open trial of oral sildenafil in antidepressant-induced sexual dysfunction. Psychotherapy & Psychosomatics, 67, 328–331.
  • Ferrante, F. M., Paggioli, J., Cherukuri, S. Arthur, G. R. (1986). The analgesic response to intravenous lidocaine in the treatment of neuropathic pain. Anesthesia & Analgesia, 82, 91–97.
  • Finch, P. M., Roberts, L. J., Price, L., Hadlow, N. C. & Pullan, P. T. (2000). Hypogonadism in patients treated with intrathecal morphine. Clinical Journal of Pain, 16, 251–254.
  • Fine, P. G. & Bubela, C. (1985). Chylothorax following celiac plexus block. Anesthesiology, 63, 454–456.
  • Herzog, A. G., Klein, P. & Jacobs, A. R. (1998). Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism. Neurology, 50, 782–784.
  • Husain, A. M., Carwile, S. T., Miller, P. P. & Radtke, R. A. (2000). Improved sexual function in three men taking lamotrigine for epilepsy. Southern Medical Journal, 93, 335–336.
  • Johnson, J. H. & Rosecrans, J. A. (1980). Blockade of ovulation by methadone in the rat: A central nervous system-mediated acute event. Journal of Pharmacology and Experimental Therapeutics, 213, 110–113.
  • Kaplan, H. S. (1974). The new sex therapy. New York: Brunner/Mazel.
  • Kaplan, S. A., Reis, R. B., Kohn, I. J., Ikeguchi, E. F., Laor, E., Te, A. E. & Martins, A. C. (1999). Safety and efficacy of sildenafil in postmenopausal women with sexual dysfunction. Urology, 53, 481–486.
  • Kuch, K., Cox, B., Evans, R. J., Watson, P. C. & Bubela, C. (1993). To what extent do anxiety and depression interact with chronic pain? Canadian Journal of Psychiatry, 38, 36–38.
  • Labbate, L. A. & Rubey, R. N. (1999). Gabapentin-induced ejaculatory failure and anorgasmia. American Journal of Psychiatry, 156, 972.
  • Leris, A. C., Stephens, J., Hines, J.E. & McNicholas, T. A. (1997). Carbamazepine-related ejaculatory failure. British Journal of Urology, 79, 485.
  • Liu, S. S. & Benzon, H. T. (2000). Outcomes and complications of acute pain management. In Practical management of pain (3rd. ed.), pp 871–889. St. Louis: Mosby.
  • Malek, C. J. & Brower, S. A. (1984). Rheumatoid arthritis: How does it influence sexuality? Rehabilitation Nursing, 9, 26–28.
  • Massie, M. J., Spiegel, L., Ledeerberg, M. S. & Holland, J. C. (1995). Psychiatric complications in cancer patients. In G. P. Murphy, W. Lawrence, Jr., & Lenhard, R. E., Jr. (Eds.), American Cancer Society textbook of clinical oncology (2nd ed.). Washington, DC: American Cancer Society.
  • Max, M. B. & Gilron, I. H. (2001). Antidepressants, muscle relaxants, and N-methyl-D-aspartate receptor antagonists. In J. D. Loweser, S. H. Butler, C. R. Chapman & D. C. Turk (Eds.), Bonica's management of pain (pp 1710–1726). Philadelphia: Lippincott Williams & Wilkins.
  • McCullough, A. (1999). Sildenafil (Viagra™) one year later: A retrospective. Sexual Dysfunction in Medicine, 1 (1), 2–7.
  • Medical Letter. (1992). Drugs that cause sexual dysfunction. New Rochelle, NY: Medical Letter, Inc.
  • Mendelson, J. H. & Mello, N. K. (1975). Plasma testosterone levels during chronic heroin use and protracted abstinence: A study of Hong Kong addicts. Clinical Pharmacology and Therapeutics, 17, 529–533.
  • Mendelson, J. H., Meyer, R. E., Ellingboe, J., Mirin, S. M. & McDougle, M. (1975). Effects of heroin and methadone on plasma cortisol and testosterone. Journal of Pharmacology and Experimental Therapeutics, 195, 296–302.
  • Monga, T. N., Tan, G., Ostermann, H. J, Monga, U. & Grabois, M. (1998). Sexuality and sexual adjustment of patients with chronic pain. Disability and Rehabilitation, 20, 317–329.
  • Montejo-Gonzalez, A. L., Llorca, G., Izquierdo, J. A., Ledesma, A., Bousono, M., Calcedo, A., Carrasco, J. L., Daniel, E., De la Gandara, J., Derecho, J., Franco, M., Gomez, M. J., Macias, J. A., Martin, T., Perez, V., Sanchez, S. & Vicens, E. (1997). SSRI-induced dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, mulicenter, and descriptive clinical study of 344 patients. Journal of Sex & Marital Therapy, 23 (3), 176–194.
  • Morrell, M. J., Sarto, G. E., Shafer, P. O., Borda, E. A., Herzog, A. & Callanan, M. (2000). Health issues for women with epilepsy: A descriptive survey to assess knowledge and awareness among healthcare providers. Journal of Women's Health & Gender Based Medicine, 9 (9), 959–965.
  • Nurnberg, H. G., Lauriello, J., Hensley, P. L., Parker, L. M. & Keith, S. J. (1999). Sildenafil for iatrogenic serotonergic antidepressant medication-induced sexual dysfunction in 4 patients. Journal of Clinical Psychiatry, 60 (1), 33–35.
  • Nurnberg, G. H., Hensley, P. L. & Lauriello, J. (2000). Sildenafil in the treatment of sexual dysfunction induced by selective serotonin reuptake inhibitors: An overview. CNS Drugs, 13 (5), 321–335.
  • Osborne, D. & Maruta, T. (1980). Sexual adjustment and chronic back pain. Medical Aspects of Human Sex, 14, 94–113.
  • Packman, P. M. & Rothchild, J. A. (1976). Morphine inhibition of ovulation: Reversal by naloxone. Endocrinology, 99, 7–10.
  • Paice, J. A. & Penn, R. D. (1995). Amenorrhea associated with intraspinal morphine (letter). Journal of Pain and Symptom Management, 10, 582–583.
  • Paice, J. A., Penn, R. D. & Ryan, W. (1994). Altered sexual function and decreased testosterone in patients receiving intraspinal opioids. Journal of Pain and Symptom Management, 9, 126–131.
  • Payne, R. (1998). Pharmacologic management of pain. In Berger, A. M., Portenoy, R. K. & Weissman, D. E. (Eds), Principles and practice of supportive oncology. Philadelphia: Lippincott-Raven Publishers.
  • Pelosi, M. A., Sama, J. C., Caterini, H. & Kaminetzky, H. A. (1974). Galactorrhea-amenorrhea syndrome associated with heroin addiction. American Journal of Obstetrics and Gynecology, 118, 966–970.
  • Penovich, P. E. (2000). The effects of epilepsy and its treatment on sexual and reproductive function. Epilepsia, 41 (suppl 2), S53–S61.
  • Portenoy, R. K. & Foley, K. M. (1990). Management of cancer pain. In Holland, J. & Rowland, A. (Eds.), Handbook of psychooncology. New York: Oxford University Press.
  • Raj, P. P. (2000). Epidural steriod injections. In P. P. Raj (Ed.), Practical management of pain (3rd edition), pp 732–743. St. Louis: Mosby.
  • Rako, S. (1999). Testosterone deficiency and supplementation for women: Matters of sexuality and health. Psychiatric Annals, 29 (1), 23–26.
  • Rosen, R. C., Lane, R. M. & Menza, M. (1999). Effects of SSRIs on sexual function. Journal of Clinical Psychopharmacology, 19, 67–85.
  • Rothschild, A. J. (2000). New directions in the treatment of anti-depressant-induced sexual dysfunction. Clinical Therapeutics, 22 (suppl A), A42–A61.
  • Rowbotham, M. C. & Petersen, K. L. (2001). Anticonvulsants and local anesthetic drugs. In J. D. Loweser, S. H. Butler, C. R. Chapman & D. C. Turk (Eds.), Bonica's management of pain (pp 1727–1735). Philadelphia: Lippincott Williams & Wilkins.
  • Rowbotham, M. C., Reisner-Keller, L. A. & Fields, H. L. (1991). Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia. Neurology, 41, 1024–1028.
  • Saberski, L., Fitzgerald, J. & Ahmad, M. (2000). Cryoneurolysis and radiofrequency lesioning. In P. P. Raj (Ed.), Practical management of pain (3rd edition), pp 753–767. St. Louis: Mosby.
  • Salerian, A. J., Deibler, W. E., Vittone, B. J., Geyer, S. P., Drell, L., Mirmirani, N., Mirczak, J. A., Byrd, W., Tunick, S. B., Wax, M. & Fleisher, S. (2000). Sildenafil for psychotropic-induced sexual dysfunction in 31 women and 61 men. Journal of Sex & Marital Therapy, 26 (2), 133–140.
  • Santen, R. J., Sofsky, J., Bilic, N. & Lippert, R. (1975). Mechanism of action of narcotics in the production of menstrual dysfunction in women. Fertility & Sterility, 26, 538–548.
  • Schover, L.R. (1998a). Sexuality & cancer: For the woman who has cancer, and her partner. New York: American Cancer Society.
  • Schover, L.R. (1998b). Sexuality & cancer: For the man who has cancer, and his partner. New York: American Cancer Society.
  • Spark, R. F. (2000). Sexual health for men: The complete guide. Cambridge, MA: Perseus Books Group.
  • Steers, W. D. (1999). Viagra—After one year. Urology, 54, 12–17.
  • Syrjala, K. L. & Roth-Roemer, S. L. (1998). Nonpharmacologic approaches to pain. In Berger, A. M., Portenoy, R. K. & Weissman, D. E. (Eds), Principles and practice of supportive oncology. Philadelphia: Lippincott-Raven Publishers.
  • Su, C. F., Liu, M. Y. & Lin, M. T. (1987). Intraventricular morphine produces pain relief, hypothermia, hyperglycaemia and increased prolactin and growth hormone levels in patients with cancer pain. Journal of Neurology, 235, 105–108.
  • Wang, C., Chan, V. & Yeung, R. T. (1978). The effect of heroin addiction on pituitary-testicular function. Clinical Endocrinology, 9, 455–461.
  • Wang, C., Swerdloff, R. S., Iranmanesh, A., Dobs, A., Snyder, P. J., Cunningham, G., Matsumoto, A. M., Weber, T. & Berman, N. (2000). Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. Journal of Clinical Endocrinology & Metabolism, 85 (8), 2839–2853.
  • Wein, A. J. & Van Arsdalen, K. N. 1988. Drug-induced male sexual dysfunction. Urology Clinics of North America, 15 (1), 23–31.
  • Wiesenfeld-Hallin, Z. & Södersten, P. (1984). Spinal opiates affect sexual behavior in rats. Nature, 309, 257–258.
  • Yamada, K., Ushio, Y., Hayakawa, T., Arita, N., Yamada, N. & Mogami, H. (1983). Effects of methylprednisolone on peritumoral brain edema: A quantification autoradiographic study. Journal of Neurosurgery, 59, 612–619.
  • Zis, A. P., Haskett, R. F., Albala, A. A. & Carroll, B. J. (1984). Morphine inhibits cortisol and stimulates prolactin secretion in man. Psychoneuroimmunology, 9, 423–427.
  • Zylicz, Z. & Mudde, A. H. (2000). Painful gynecomastia: An unusual toxicity of gabapentin. Journal of Pain & Symptom Management, 20, 2–3.

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