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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 44, 2022 - Issue 8
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Original Research Paper

LncRNA HAND2-AS1 attenuates glioma cell proliferation, invasion and migration by targeting CDK6

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Pages 677-683 | Received 20 Jun 2021, Accepted 26 Jan 2022, Published online: 12 May 2022

References

  • Bayat N, Ebrahimi-Barough S, Norouzi-Javidan A, et al. Apoptotic effect of atorvastatin in glioblastoma spheroids tumor cultured in fibrin gel. Biomed Pharmacothe. 2016;84:1959–1966.
  • Rousseau A, Mokhtari K, Duyckaerts C. The 2007 WHO classification of tumors of the central nervous system - what has changed?. Curr Opin Neurol. 2008;21:720–727.
  • Barnholtz-Sloan JS, Ostrom QT, Cote D. Epidemiology of brain tumors. Neurol Clin. 2018;36:395–419.
  • Darlix A, Zouaoui S, Rigau V, et al. Epidemiology for primary brain tumors: a nationwide population-based study. J Neurooncol. 2017;131:525–546.
  • McNeill KA. Epidemiology of brain tumors. Neurol Clin. 2016;34:981–998.
  • Carninci P, Kasukawa T, Katayama S, et al. The transcriptional landscape of the mammalian genome. Science. 2005;309:1559–1563.
  • Feng S, Yao J, Chen Y, et al. Expression and functional role of reprogramming-related long noncoding RNA (lincRNA-ROR) in Glioma. J Mol Neurosci. 2015;56:623–630.
  • Hung T, Chang HY. Long noncoding RNA in genome regulation: prospects and mechanisms. RNA Biol. 2010;7:582–585.
  • Peng Z, Liu C, Wu M. New insights into long noncoding RNAs and their roles in glioma. Mol Cancer. 2018;17:61.
  • Wang Y, Wang Y, Li J, et al. CRNDE, a long-noncoding RNA, promotes glioma cell growth and invasion through mTOR signaling. Cancer Lett. 2015;367:122–128.
  • Chen J, Lin Y, Jia Y, et al. LncRNA HAND2-AS1 exerts anti-oncogenic effects on ovarian cancer via restoration of BCL2L11 as a sponge of microRNA-340-5p. J Cell Physiol. 2019;234:23421–23436.
  • Kang Y, Zhu X, Xu Y, et al. Energy stress-induced lncRNA HAND2-AS1 represses HIF1alpha-mediated energy metabolism and inhibits osteosarcoma progression. Am J Cancer Res. 2018;8:526–537.
  • Wang Y, Zhu P, Luo J, et al. LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling. EMBO J. 2019;38:e101110.
  • Zhou J, Lin J, Zhang H, et al. LncRNA HAND2-AS1 sponging miR-1275 suppresses colorectal cancer progression by upregulating KLF14. Biochem Biophys Res Commun. 2018;503:1848–1853.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402–408.
  • Mattick JS. The genetic signatures of noncoding RNAs. PLoS Genet. 2009;5:e1000459.
  • Wilusz JE, Sunwoo H, Spector DL. Long noncoding RNAs: functional surprises from the RNA world. Genes Dev. 2009;23:1494–1504.
  • Gupta RA, Shah N, Wang KC, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010;464:1071–1076.
  • Jiang Z, Li L, Hou Z, et al. LncRNA HAND2-AS1 inhibits 5-fluorouracil resistance by modulating miR-20a/PDCD4 axis in colorectal cancer. Cell Signal. 2020;66:109483.
  • Xu Z, Lv H, Wang Y, et al. HAND2-AS1 inhibits gastric adenocarcinoma cells proliferation and aerobic glycolysis via miRNAs sponge. Cancer Manag Res. 2020;12:3053–3068.
  • Chen S, Wang J. HAND2-AS1 inhibits invasion and metastasis of cervical cancer cells via microRNA-330-5p-mediated LDOC1. Cancer Cell Int. 2019;19:353.
  • Li Z, Zhang J, Zheng H, et al. Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme. J Exp Clin Cancer Res. 2019;38:380.
  • Chen X, Li Y, Zuo C, et al. Long non-coding RNA H19 regulates glioma cell growth and metastasis via miR-200a-Mediated CDK6 and ZEB1 expression. Front Oncol. 2021;11:757650.
  • Zhang Q, Wang G, Xu L, et al. Long non-coding RNA LINC00473 promotes glioma cells proliferation and invasion by impairing miR-637/CDK6 axis. Artif Cells Nanomed Biotechnol. 2019;47:3896–3903.
  • Tadesse S, Yu M, Kumarasiri M, et al. Targeting CDK6 in cancer: state of the art and new insights. Cell Cycle. 2015;14:3220–3230.
  • Raleigh DR, Choksi PK, Krup AL, et al. Hedgehog signaling drives medulloblastoma growth via CDK6. J Clin Invest. 2018;128:120–124.
  • Thomson DW, Dinger ME. Endogenous microRNA sponges: evidence and controversy. Nat Rev Genet. 2016;17:272–283.

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