Hypercapnic hypoxia improves cognitive and motor functions of children with cerebral palsy

References

• Satriotomo I, Dale EA, Dahlberg JM, et al. Repetitive acute intermittent hypoxia increases expression of proteins associated with plasticity in the phrenic motor nucleus. Exp Neurol. 2012;237(1):103–115.
   PubMed Web of Science ®Google Scholar
• Yatsenko KV, Berezovskii VA, Deyeva JV. Effects of intermittent normobaric hypoxia on the state of the CNS and cerebral circulation in children with cerebral palsy. Fiziol Zh. 2012;58(3):77–84.
   PubMedGoogle Scholar
• Sharp FR, Ran R, Lu A, et al. Hypoxic preconditioning protects against ischemic brain injury. NeuroRx. 2004;1(1):26–35.
   PubMedGoogle Scholar
• Zhou Q, Cao B, Niu L. Effects of permissive hypercapnia on transient global cerebral ischemia–reperfusion injury in rats. Anesthesiology. 2010;112(2):288–297.
   PubMed Web of Science ®Google Scholar
• Brambrink A, Orfanakis A. Therapeutic hypercapnia” after ischemic brain injury: is there a potential for neuroprotection?//. Anesthesiology. 2010;112(2):274–276.
   PubMed Web of Science ®Google Scholar
• Tao T, Liu Y, Zhang J. Therapeutic hypercapnia improves functional recovery and attenuates injury via antiapoptotic mechanisms in a rat focal cerebral ischemia/reperfusion model. Brain Res. 2013;1533:52–62.
   PubMed Web of Science ®Google Scholar
• Vannucci RC, Towfighi J, Heitjan DF, et al. Carbon dioxide protects the perinatal brain from hypoxic-ischemic damage: an experimental study in the immature rat. Pediatrics 1995;95(6):868–874.
   PubMed Web of Science ®Google Scholar
• Doman RJ, Spitz EB, Zucman E, et al. Children with severe brain injuries. Neurological organization in terms of mobility. JAMA. 1960;174(3):257–262.
   PubMed Web of Science ®Google Scholar
• Ziring PR, Brazdziunas D, Cooley WC, et al. American academy of pediatrics. Committee on children with disabilities. The treatment of neurologically impaired children using patterning. Pediatrics. 1999;104(5 Pt 1):1149–1151.
   PubMed Web of Science ®Google Scholar
• Kuznetsova DV, Kulikov VP. Cerebrovascular and systemic hemodynamic response to carbon dioxide in humans. Blood Press Monit. 2014;19(2):81–89.
   PubMed Web of Science ®Google Scholar
• Kulikov VP, Bespalov AG, Yakushev NN. The effectiveness of training with hypercapnic hypoxia in the rehabilitation of ischemic brain damage in the experiment. Bulletin of Restorative Medicine. 2008, 2:59–61. Russian.
   Google Scholar
• Alekseeva TM, Kovzelev PD, Topuzova MP, et al. Hypercapnic-hypoxic respiratory training as a method of post-conditioning in stroke suvivors. Arterial Hypertension. 2019, 25(2):134–142. Russian.
   Google Scholar
• Smirnov KV, Smirnova YV, Kulikov VP, et al. Respiratory hypercapnic-hypoxic training is an effective component of complex therapy of polyneuropathy in children with diabetes type 1. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(3):32–38. Russian.
   PubMedGoogle Scholar
• Russell DJ, Avery LM, Walter SD, et al. Development and validation of item sets to improve efficiency of administration of the 66-item gross motor function measure in children with cerebral palsy. Dev Med Child Neurol. 2010;52(2):48–54.
   PubMed Web of Science ®Google Scholar
• Palisano RJ, Rosenbaum P, Bartlett D, et al. Content validity of the expanded and revised gross motor function classification system. Dev Med Child Neurol. 2008 Oct;50(10):744–750.
   PubMed Web of Science ®Google Scholar
• Hidecker MJ, Paneth N, Rosenbaum PL, et al. Developing and validating the communication function classification system for individuals with cerebral palsy. Dev Med Child Neurol. 2011 Aug;53(8):704–710. Epub 2011 Jun 27. PMID: 21707596; PMCID: PMC3130799.
   PubMed Web of Science ®Google Scholar
• Eliasson A, Krumlinde-Sundholm L, Rösblad B, et al. The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability. Dev Med Child Neurol. 2007;48(7):549–554.
   Web of Science ®Google Scholar
• Kulikov VP, Smirnova Yu V, Smirnov KV. Evaluation of the excitability of motor neurons of the human cerebral cortex by the method of magnetic stimulation. Human Physiol. 2004;30(3):133–135. Russian.
   Google Scholar
• Van Der Werf YD, Paus T. The neural response to transcranial magnetic stimulation of the human motor cortex. I. Intracortical and cortico-cortical contributions. Exp Brain Res. 2006;175(2):231–245.
   PubMed Web of Science ®Google Scholar
• Tregub P, Kulikov V, Motin Y, et al. Combined exposure to hypercapnia and hypoxia provides its maximum neuroprotective effect during focal ischemic injury in the brain. J Stroke Cerebrovascular Dis. 2015;24(2):381–387.
   PubMed Web of Science ®Google Scholar
• Zhou W, Liu W. Hypercapnia and hypocapnia in neonates. World J Pediatr. 2008;4(3):192–196.
   PubMed Web of Science ®Google Scholar
• Ma J, Ye H. Effects of permissive hypercapnia on pulmonary and neurodevelopmental sequelae in extremely low birth weight infants: a meta-analysis. Springerplus. 2016;5(1):764.
   PubMedGoogle Scholar
• Obrenovitch TP. Molecular physiology of preconditioning-induced brain tolerance to ischemia. Physiol Rev. 2008;88(1):211–247.
   PubMed Web of Science ®Google Scholar
• Siafakas NM, Jordan M, Wagner H. Diaphragmatic angiogenic growth factor mRNA responses to increased ventilation caused by hypoxia and hypercapnia. Eur Respir J. 2001;17(4):681–687.
   PubMed Web of Science ®Google Scholar
• Zakynthinos S, Katsaounou P, Karatza MH. Antioxidants increase the ventilatory response to hyperoxic hypercapnia. Am J Respir Crit Care Med. 2007;175(1):62–68.
   PubMed Web of Science ®Google Scholar
• Vermeulen TD, Benbaruj J, Brown CV, et al. Acute intermittent hypercapnic hypoxia and cerebral neurovascular coupling in males and females. Exp Neurol. 2020 Dec;334: 113441. Epub 2020 Sep 3. PMID: 32890469
   PubMed Web of Science ®Google Scholar
• Serebrovskaya TV, Xi L. Intermittent hypoxia in childhood: the harmful consequences versus potential benefits of therapeutic uses. Front Pediatr. 2015;19(3):44.
   Google Scholar
• Welch JF. Intermittent hypercapnic hypoxia: a model to study human respiratory motor plasticity? J Physiol. 2021 Apr;599(7):1951–1953. Epub 2021 Jan 25. PMID: 33480443.
   PubMed Web of Science ®Google Scholar
• Deacon NL, McEvoy RD, Stadler DL, et al. Intermittent hypercapnic hypoxia during sleep does not induce ventilatory long-term facilitation in healthy males. J Appl Physiol. 2017 Sep 1;123(3):534–543. (1985). Epub 2017 Jun 15. PMID: 28620058.
   PubMed Web of Science ®Google Scholar
• Kulikov VP, Tregub PP, Osipov IS, et al. Hypercapnic hypoxia as a potential means to extend life expectancy and improve physiological activity in mice. Biogerontology. 2019 Oct;20(5):677–686. Epub 2019 Jul 15.
   PubMed Web of Science ®Google Scholar