Black Tea-Induced Decrease in IL-10 and TGF-β of Tumor Cells Promotes Th1/Tc1 Response in Tumor Bearer

References

• Yang , L and Carbone , D P . 2004 . Tumor-host immune interactions and dendritic cell dysfunction . Adv Cancer Res , 92 : 13 – 27 .
   PubMed Web of Science ®Google Scholar
• Sheu , B C , Lin , R H , Lien , H C , Ho , H N , Hsu , S M and Huang , S C . 2001 . Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer . J Immunol , 167 : 2972 – 2978 .
   PubMed Web of Science ®Google Scholar
• Kidd , P . 2003 . Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease . Altern Med Rev , 8 : 8223 – 8246 .
   Google Scholar
• Smith , K A . 1988 . Interleukin-2: inception, impact, and implications . Science , 240 : 1169 – 1176 .
   PubMed Web of Science ®Google Scholar
• Knutson , K L and Disis , M L . 2005 . Tumor antigen-specific T helper cells in cancer immunity and immunotherapy . Cancer Immunol Immunother , 54 : 721 – 728 .
   PubMed Web of Science ®Google Scholar
• Li , R , Ruttinger , D , Li , R , Si , L S and Wang , Y L . 2003 . Analysis of the immunological microenvironment at the tumor site in patients with non-small cell lung cancer . Langenbecks Arch Surg , 388 : 406 – 412 .
   PubMedGoogle Scholar
• Zhang , Q , Yang , X , Pins , M , Javonovic , B Kuzel , T . 2005 . Adoptive transfer of tumor-reactive transforming growth factor-beta-insensitive CD8+ T cells: eradication of autologous mouse prostate cancer . Cancer Res , 65 : 1761 – 1769 .
   PubMed Web of Science ®Google Scholar
• Beauchamp , R D , Sheng , H M , Bascom , C C , Miller , D A Lyons , R M . 1992 . Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-β 1 . Endocrinology , 130 : 2476 – 2486 .
   PubMedGoogle Scholar
• Lüscher , U , Filgueira , L , Juretic , A , Zuber , M Lüscher , N J . 1994 . The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumor-in-filtrating lymphocytes . Int J Cancer , 57 : 612 – 619 .
   PubMed Web of Science ®Google Scholar
• Merogi , A J , Marrogi , A J , Ramesh , R , Robinson , W R Fermin , C D . 1997 . Tumor-host interaction: analysis of cytokines, growth factors, and tumor-infiltrating lymphocytes in ovarian carcinoma . Hum Pathol , 28 : 321 – 331 .
   PubMed Web of Science ®Google Scholar
• Huang , M , Wang , J , Lee , P , Sharma , S Mao , J T . 1995 . Human non-small cell lung cancer cells express a type 2 cytokine pattern . Cancer Res , 55 : 3847 – 3853 .
   PubMed Web of Science ®Google Scholar
• Kanazawa , M , Yoshihara , K , Abe , H , Iwadate , M Watanabe , K . 2005 . Effects of PSK on T and dendritic cells differentiation in gastric or colorectal cancer patients . Anticancer Res , 25 : 443 – 449 .
   PubMedGoogle Scholar
• Mukherjee , P , Ginardi , A R , Madsen , C S , Tinder , T L Jacobs , F . 2001 . MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment . Glycoconj J , 18 : 931 – 942 .
   PubMed Web of Science ®Google Scholar
• Arteaga , C L , Hurd , S D , Winnier , A R , Johnson , M D Fendly , B M . 1993 . Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity: implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression . J Clin Invest , 92 : 2569 – 2576 .
   PubMed Web of Science ®Google Scholar
• Hoefer , M and Anderer , F A . 1995 . Anti-(transforming growth factor beta) antibodies with predefined specificity inhibit metastasis of highly tumorigenic human xenotransplants in nu/nu mice . Cancer Immunol Immunother , 41 : 302 – 308 .
   PubMed Web of Science ®Google Scholar
• Won , J , Kim , H , Park , E J , Hong , Y Kim , S J . 1999 . Tumorigenicity of mouse thymoma is suppressed by soluble type II transforming growth factor beta receptor therapy . Cancer Res , 59 : 1273 – 1277 .
   PubMed Web of Science ®Google Scholar
• Yang , Y A , Dukhanina , O , Tang , B , Mamura , M Letterio , J J . 2002 . Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects . J Clin Invest , 109 : 1607 – 1615 .
   PubMed Web of Science ®Google Scholar
• Gorelik , L and Flavell , R A . 2001 . Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells . Nat Med , 7 : 1118 – 1122 .
   PubMed Web of Science ®Google Scholar
• Carter , L L and Dutton , R W . 1996 . Type 1 and type 2: a fundamental dichotomy for all T-cells . Curr Opin Immunol , 8 : 336 – 342 .
   PubMed Web of Science ®Google Scholar
• Tsuji , T , Yasukawa , M , Matsuzaki , J , Ohkuri , T Chamoto , K . 2005 . Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes . Blood , 106 : 470 – 476 .
   PubMed Web of Science ®Google Scholar
• Weisburger , J H . 1999 . Mechanisms of action of antioxidants as exemplified in vegetables, tomatoes and tea . Food Chem Toxicol , 37 : 943 – 948 .
   PubMed Web of Science ®Google Scholar
• Zvetkova , E , Wirleitner , B , Tram , N T , Schennach , H and Fuchs , D . 2001 . Aqueous extracts of Crinum latifolium(L.) and Camellia sinensis show immunomodulatory properties in human peripheral blood mononuclear cells . Int Immunopharmacol , 1 : 2143 – 2150 .
   PubMedGoogle Scholar
• Bhattacharyya , A , Choudhuri , T , Pal , S , Chattopadhyay , S Datta , G K . 2003 . Apoptogenic effects of black tea on Ehrlich's ascites carcinoma cell . Carcinogenesis , 24 : 75 – 80 .
   PubMed Web of Science ®Google Scholar
• Bhattacharyya , A , Mandal , D , Lahiry , L , Sa , G and Das , T . 2004 . Black tea protects immunocytes from tumor-induced apoptosis by changing Bcl-2/Bax ratio . Cancer Lett , 209 : 147 – 154 .
   PubMed Web of Science ®Google Scholar
• Mandal , D , Lahiry , L , Bhattacharyya , A , Chattopadhyay , S Siddiqi , M . 2005 . Black tea protects thymocytes in tumor-bearing animals by differential regulation of intracellular ROS in tumor cells and thymocytes . J Environ Pathol Toxicol Oncol , 24 : 91 – 104 .
   PubMedGoogle Scholar
• Basu , R , Bhaumik , S , Basu , J M , Naskar , K De , T . 2005 . Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis . J Immunol , 174 : 7160 – 7171 .
   PubMed Web of Science ®Google Scholar
• Ruegemer , J J , Ho , S N , Augustine , J A , Schlager , J W Bell , M P . 1990 . Regulatory effects of transforming growth factor-β on IL-2- and IL-4-dependent T cell-cycle progression . J Immunol , 144 : 1767 – 1776 .
   PubMed Web of Science ®Google Scholar
• Malmberg , K J . 2004 . Effective immunotherapy against cancer: a question of overcoming immune suppression and immune escape? . Cancer Immunol Immunother , 53 : 879 – 892 .
   PubMed Web of Science ®Google Scholar
• de Visser , K E and Kast , W M . 1999 . Effects of TGF-βn the immune system: implications for cancer immunotherapy . Leukemia , 13 : 1188 – 1199 .
   PubMed Web of Science ®Google Scholar
• Torre-Amione , G , Beauchamp , R D , Koeppen , H , Park , B H Schreiber , H . 1990 . A highly immunogenic tumor transfected with a murine transforming growth factor type β 1 cDNA escapes immune surveillance . Proc Natl Acad Sci USA , 87 : 1486 – 1490 .
   PubMed Web of Science ®Google Scholar
• Schiött , Å , Widergren , B , Sjögren , H O and Lindvall , M . 1999 . Transforming growth factor-β 1, a strong costimulator of rat T-cell activation promoting a shift towards a Th2-like cytokine profile . Immunol Lett , 67 : 131 – 139 .
   PubMedGoogle Scholar
• Salazar-Onfray , F . 1999 . Interleukin-10: a cytokine used by tumors to escape immunosurveillance . Med Oncol , 16 : 86 – 94 .
   PubMed Web of Science ®Google Scholar
• Steinbrink , K , Jonuleit , H , Müller , G , Schuler , G Knop , J . 1999 . Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8+ T cells resulting in a failure to lyse tumor cells . Blood , 93 : 1634 – 1642 .
   PubMed Web of Science ®Google Scholar
• Maeda , H and Shiraishi , A . 1996 . TGF-β contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice . J Immunol , 156 : 73 – 78 .
   PubMed Web of Science ®Google Scholar
• Flescher , E , Ledbetter , J A , Schieven , G L , Vela-Roch , N Fossum , D . 1994 . Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction . J Immunol , 153 : 4880 – 4889 .
   PubMed Web of Science ®Google Scholar
• Luczaj , W and Skrzydlewska , E . 2005 . Antioxidative properties of black tea . Prev Med , 40 : 910 – 918 .
   PubMed Web of Science ®Google Scholar
• Kamath , A B , Wang , L , Das , H , Li , L Reinhold , V N . 2003 . Antigens in tea-beverage prime human Vgamma 2Vdelta 2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses . Proc Natl Acad Sci USA , 100 : 6009 – 6014 .
   PubMed Web of Science ®Google Scholar
• Okita , R , Saeki , T , Takashima , S , Yamaguchi , Y and Toge , T . 2005 . CD4+CD25+ regulatory T cells in the peripheral blood of patients with breast cancer and non-small cell lung cancer . Oncol Rep , 14 : 1269 – 1273 .
   PubMed Web of Science ®Google Scholar
• Hitoglou-Hatzi , S , Hatzistilianou , M , Gougoustamou , D , Rekliti , A Agguridaki , Ch . 2005 . Serum adenosine deaminase and procalcitonin concentrations in neutropenic febrile children with acute lymphoblastic leukaemia . Clin Exp Med , 555 : 60 – 65 .
   Google Scholar