Niacin Supplementation Decreases the Incidence of Alkylation-Induced Nonlymphocytic Leukemia in Long-Evans Rats

REFERENCES

• Boffetta , P and Kaldor , J M . 1994 . Secondary malignancies following cancer chemotherapy . Acta Oncol , 33 : 591 – 598 .
   PubMed Web of Science ®Google Scholar
• Tucker , M A . 1993 . “ Secondary cancers ” . In Cancer: Principles and Practice of Oncology , Edited by: DeVita , V T , Hellman , S and Rosenberg , S A . 2407 – 2416 . Philadelphia, PA : JB Lippincott Co. .
   Google Scholar
• Felix , C A . 1998 . Secondary leukemias induced by topoisomerase-targeted drugs . Biochim Biophys Acta , 1400 : 233 – 255 .
   PubMed Web of Science ®Google Scholar
• Smith , M A , McCaffrey , R P and Karp , J E . 1996 . The secondary leukemias: challenges and research directions . J Natl Cancer Inst , 88 : 407 – 418 .
   PubMed Web of Science ®Google Scholar
• Levine , E G and Bloomfield , C D . 1992 . Leukemias and myelodysplastic syndromes secondary to drug, radiation, and environmental exposure . Semin Oncol , 19 : 47 – 84 .
   PubMed Web of Science ®Google Scholar
• Leone , G , Voso , M T , Sica , S , Morosetti , R and Pagano , L . 2001 . Therapy related leukemias: susceptibility, prevention and treatment . Leuk Lymphoma , 41 : 255 – 276 .
   PubMed Web of Science ®Google Scholar
• Boyonoski , A C , Gallacher , L M , ApSimon , M M , Jacobs , R M Shah , G M . 2000 . Niacin deficiency in rats increases the severity of ethylnitrosourea-induced anemia and leukopenia . J Nutr , 130 : 1102 – 1107 .
   PubMed Web of Science ®Google Scholar
• Boyonoski , A C , Spronck , J C , Gallacher , L M , Jacobs , R M Shah , G M . 2002 . Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats . J Nutr , 132 : 108 – 114 .
   PubMed Web of Science ®Google Scholar
• Boyonoski , A C , Spronck , J C , Jacobs , R M , Shah , G M Poirier , G G . 2002 . Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats . J Nutr , 132 : 115 – 120 .
   PubMed Web of Science ®Google Scholar
• Shibuya , T and Morimoto , K . 1993 . A review of the genotoxicity of 1-ethyl-1-nitrosourea . Mutat Res , 297 : 3 – 38 .
   PubMed Web of Science ®Google Scholar
• Noveroske , J K , Weber , J S and Justice , M J . 2000 . The mutagenic action of N-ethyl-N-nitrosourea in the mouse . Mamm Genome , 11 : 478 – 483 .
   PubMed Web of Science ®Google Scholar
• Shulman , L N . 1993 . The biology of alkylating-agent cellular injury . Hematol Oncol Clin North Am , 7 : 325 – 335 .
   PubMed Web of Science ®Google Scholar
• Eisenbrand , G , Muller , N , Denkel , E and Sterzel , W . 1986 . DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds . J Cancer Res Clin Oncol , 112 : 196 – 204 .
   PubMed Web of Science ®Google Scholar
• Dreizen , S , McCredie , K B , Keating , M J and Andersson , B S . 1990 . Nutritional deficiencies in patients receiving cancer chemotherapy . Postgrad Med , 87 : 163 – 167 . 170
   PubMed Web of Science ®Google Scholar
• Inculet , R I , Norton , J A , Nichoalds , G E , Maher , M M White , D E . 1987 . Water-soluble vitamins in cancer patients on parenteral nutrition: a prospective study . J Parenter Enteral Nutr , 11 : 243 – 249 .
   PubMed Web of Science ®Google Scholar
• Stevens , H P , Ostlere , L S , Begent , R H , Dooley , J S and Rustin , M H . 1993 . Pellagra secondary to 5-fluorouracil . Br J Dermatol , 128 : 578 – 580 .
   PubMed Web of Science ®Google Scholar
• Kirkland , J B . 2003 . Niacin and carcinogenesis . Nutr Cancer , 46 : 110 – 118 .
   PubMed Web of Science ®Google Scholar
• Gagne , J P , Hendzel , M J , Droit , A and Poirier , G G . 2006 . The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives . Curr Opin Cell Biol , 18 : 145 – 151 .
   PubMed Web of Science ®Google Scholar
• Spronck , J C and Kirkland , J B . 2002 . Niacin deficiency increases spontaneous and etoposide-induced chromosomal instability in rat bone marrow cells in vivo . Mutat Res , 508 : 83 – 97 .
   PubMed Web of Science ®Google Scholar
• Kostecki , L M , Thomas , M , Linford , G , Lizotte , M , Toxopeus , L , Bartleman , A P and Kirkland , J B . 2007 . Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow . Mutat Res , 625 : 50 – 61 .
   PubMed Web of Science ®Google Scholar
• Shisa , H and Hiai , H . 1985 . Genetically determined susceptibility of Fischer 344 rats to propylnitrosourea-induced thymic lymphomas . Cancer Res , 45 : 1483 – 1487 .
   PubMed Web of Science ®Google Scholar
• Shah , G M , Le Rhun , Y , Sutarjono , I and Kirkland , J B . 2002 . Niacin deficient SKH-1 mice are more susceptible to ultraviolet B radiation-induced skin carcinogenesis . Cancer Res , 131 ( 11Suppl ) : 3150S
   Google Scholar
• Odashima , S , Ogiu , T and Maekawa , A . 1975 . Leukemias induced by 1-butyl- and 1-propyl-1-nitrosoureas in the rat . Bibl Haematol , : 107 – 115 .
   PubMedGoogle Scholar
• Shisa , H and Hiai , H . 1985 . Genetically determined susceptibility of Fischer 344 rats to propylnitrosourea-induced thymic lymphomas . Cancer Res , 45 : 1483 – 1487 .
   PubMed Web of Science ®Google Scholar
• Rawling , J M , ApSimon , M M and Kirkland , J B . 1996 . Lung poly(ADP-ribose) and NAD+ concentrations during hyperoxia and niacin deficiency in the Fischer-344 rat . Free Radic Biol Med , 20 : 865 – 871 .
   PubMed Web of Science ®Google Scholar
• Jackson , T M , Rawling , J M , Roebuck , B D and Kirkland , J B . 1995 . Large supplements of nicotinic acid and nicotinamide increase tissue NAD+ and poly(ADP-ribose) levels but do not affect diethylnitrosamine-induced altered hepatic foci in Fischer-344 rats . J Nutr , 125 : 1455 – 1461 .
   PubMed Web of Science ®Google Scholar
• Rawling , J M , Jackson , T M , Roebuck , B D , Poirier , G G and Kirkland , J B . 1995 . The effect of niacin deficiency on diethylnitrosamine-induced hepatic poly(ADP-ribose) levels and altered hepatic foci in the Fischer-344 rat . Nutr Cancer , 24 : 111 – 119 .
   PubMed Web of Science ®Google Scholar
• Shah , G M , Poirier , D , Duchaine , C , Brochu , G Desnoyers , S . 1995 . Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo . Anal Biochem , 227 : 1 – 13 .
   PubMed Web of Science ®Google Scholar
• Rawling , J M , Jackson , T M , Driscoll , E R and Kirkland , J B . 1994 . Dietary niacin deficiency lowers tissue poly(ADP-ribose) and NAD+ concentrations in Fischer-344 rats . J Nutr , 124 : 1597 – 1603 .
   PubMed Web of Science ®Google Scholar
• Spronck , J C , Nickerson , J L and Kirkland , J B . 2007 . Niacin deficiency alters p53 expression and impairs etoposide-induced cell cycle arrest and apoptosis in rat bone marrow cells . Nutr Cancer , 57 : 88 – 99 .
   PubMed Web of Science ®Google Scholar
• Hong , S J , Dawson , T M and Dawson , V L . 2004 . Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling . Trends Pharmacol Sci , 25 : 259 – 264 .
   PubMed Web of Science ®Google Scholar